This book describes the background to Paul Ehrlich's immunological works and theories and delves into the substance of his experiments in great detail. By exploring these early developments in immunology, the book lays the foundation for modern concepts, providing immunologists, biomedical researchers, and students the context for the discoveries in their field.

Key Features

the selectionist theory of antibody formation kinetics of primary and secondary antibody response quantitative methods of measurement of antigens and antibody demonstration of passive transfer of immunity from mother to foetus


Immunologists, virologists, geneticists, molecular biologists, hematologists, and science historians.

Table of Contents

List of Plates. Introduction by Sir Gustav Nossal. Preface. The Background to Ehrlich's Immunology: Origins of the Receptor Theory. On Ricin and Abrin: Quantitation Enters Immunity Research. The Value of Mother's Milk: The Founding of Pediatric Immunology. The Standardization of Toxins and Antitoxins. The Toxin-Antitoxin Reaction: Theory Outpaces Data. The Side-Chain Theory of Antibody Formation. Immune Hemolysis: Bordet Challenges Ehrlich. New Scientific Challenges. Ehrlich's Scientific Style. Appendix A. Paul Ehrlich's Honors. Appendix B. Paul Ehrlich's Scientific Bibliography. Name Index. Subject Index.


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© 2002
Academic Press
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About the author

Arthur Silverstein

Affiliations and Expertise

The Johns Hopkins University School of Medicine, Baltimore, MD, USA


" gives a rich and detailed overview of the intellectual development of Ehrlich's immunology"-MEDICAL HISTORY (April 2003) @qu:"It is a sophisticated, closely argued, and clearly written analysis of Ehrlich's contributions to immunology. The adroit use of a wealth of original sources enriches and strengthens the text." @source:--Robert S. Schwartz M.D. in NEW ENGLAND JOURNAL OF MEDICINE (March 2002)