Pathophysiology, Risk factors and Management of Chronic Heart Failure, Volume 2

Pathophysiology, Risk factors and Management of Chronic Heart Failure, Volume 2

1st Edition - September 1, 2022

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  • Editors: Ram Singh, Jan Fedacko, Krasimira Hristova, Galal Nagib Elkilany
  • Paperback ISBN: 9780128229705

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Chronic Heart Failure: Management, Therapies, and Guidelines is the second of two separate but closely related volumes which aim to provide an inclusive overview on Chronic Heart Failure (CHF). This second volume is focused on the therapies of various kinds, management, guidelines and future advances in heart failure. It explains the uncertainties and issues in pharmacological therapies in CHF, along with a number of new treatment options such as gene therapy, cell implantation therapy, invasive and surgical interventions, and non-pharmacological therapies, which would include dietary interventions, holistic approaches, and physical training. It discusses in depth the management of patients with heart failure, and concludes with detailed and updated guidelines from the International College of Cardiology, as well as future research directions and advances. These 2 separate volumes serve as essential references to both researchers and practicing clinicians, proposing novel methods of research by using behavioural and environmental risk factors as intervention agent, as well as discussing deficiency in the present approaches in management of HF and proposing new methods of early diagnosis and therapies for the clinical management of CHF.

Key Features

  • Includes a number new and controversial topics: Pharmacological therapy; Gene therapy, Cell implantation, hormone replacement therapy; Therapy and management of arrhythmias, acute heart failure, paediatric heart failure; Invasive and surgical approaches to CHF; Non pharmalogical approaches such as dietary interventions, holistic approaches, and physical training; Updated guidelines from the International college of cardiology for management of heart failure
  • Includes never-published tables and figures to aid understanding of the topics
  • Contributions from international leading experts in the field, written with the aim of serving both researchers and practicing clinicians


Cardiologists, echocardiographists, researchers, physicians, biochemists, pharmacologists, pharmacists, nutrition scientists, dietitians, experts developing guidelines, endocrinologists, nephrologists, neurologist, neuro-endocrinologists, community medicine and public health workers and policy makers

Table of Contents

  • Section 9. Therapies in chronic heart failure
    1. Pharmacological therapy of chronic heart failure
    ­2. Management of arrhythmia during heart failure
    3. Ivabradine therapy (hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers).
    4. Therapy in acute heart failure
    5. Gene Therapy in Heart Failure
    6. Cell Implantation Therapy in Heart Failure
    7. Diagnosis and Treatment of Paediatric Heart Failure
    8. Effects of Hormone Replacement Therapy on Cardiovascular Disease in Postmenopausal Women
    9. Health Care Burden of Cardiorespiratory Diseases and Heart Failure Caused by Air Pollutants and Microparticles

    Section 10. Invasive Therapies in chronic heart failure
    10. Intra-aortic balloon pumping during heart failure
    11. Vagal nerve stimulation for treatment of heart failure
    12. Ventricular assistance - role of CRT
    13. Cardiac transplantation
    14. Dialysis and hemofiltration during heart failure
    15. Pathogenesis and Therapy of the thrombosis in patients with heart failure
    16. Surgical Approaches in heart failure

    Section 11. Non-pharmacological therapies in heart failure
    17. Holistic Approaches in the Management of HF
    18. Nutritional intervention in HF
    19. Physical training in HF
    20. Yoga therapy for HF
    21. Chronic Heart Failure Management in the domiciliary and care home environment and statistical methodology
    22. Remote Monitoring of Patients With Biventricular Defibrillators Through the Carelink System Improves the Management of Arrhythmias and Heart Failure Episode

    Section 12. Guidelines in CHF
    23. 2020 Guidelines of the International College of Cardiology for Management of HF
    24. Future advances in the diagnosis and management of chronic heart failure
    25. Role of Stalwarts of cardiomyocyte dysfunction and CHF

Product details

  • No. of pages: 410
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: September 1, 2022
  • Imprint: Academic Press
  • Paperback ISBN: 9780128229705

About the Editors

Ram Singh

Dr. Ram B Singh is president of the Tsim Tsoum Insitutute in Krakow, Poland. He's an honorary fellow of the Halberg Chronobiology Centre, a member of the Russian Academy of Medical Sciences, a fellow of the International Academy of Cardiovascular Sciences, and former president and founder of the Indian Society of Hypertension, International College of Cardiology, and International College of Nutrition. He is the editor of the World Heart Journal and former professor of medicine at Subharti Medical College. He has contributed over 500 research papers to peer reviewed journals and has edited seven books.

Affiliations and Expertise

Consultant Neuro-cardiologist, Halberg Hospital and Research Institute, Moradabad-10(UP), India

Jan Fedacko

Jan Fedacko, MD, PhD, FICC, FICN is Assistant Professor at Department of Medicine and Centre of Excellency for Atherosclerosis Research at Louis Pasteur University Hospital and Pavol Jozef Safarik University in Kosice, Slovak Republic. After obtaining a diploma in General Medicine of Pavol Jozef Safarik University in Kosice, Slovak Republic (2005) the Ph.D. study (negative pleiotropic effect of the statins and possibilities of its treatment) was completed in year 2010. He is member of executive board of International College of Cardiology, member of International College of Clinical Nutrition, Slovak Association of Cardiology, Slovak Association of Atherosclerosis and member of Editorial Advisory Board of several journals. In the clinical and research area he is focused on preventive cardiology, prevention and treatment of the atherosclerosis deseases, as well as in cardiac imagineg techniques. He has published several papers in domestic and international journals, including several international lectures.

Affiliations and Expertise

Associate Professor, 3rd Interna Clinic,Faculty of Medicine, PJ Safaric University, Kosice, Slovakia

Krasimira Hristova

Assoc. Prof. Dr. Krasimira Hristova is specialist cardiologist, expert of echocardiography at University National Heart Hospital, Sofia, Bulgaria and consulting cardiologist at Nadezhda Women’s Hospital , Sofia, Bulgaria . She earned a PhD in applying the newest echocardiographic methods for evaluating the myocardial deformation in patients, following acute myocardial infarction. Assoc. Prof. Hristova specialized in top-ranked universities in Austria and Belgium. She has earned a master’s degree in Advance Medical Imaging in cardiology at Catholic University Leuven, Belgium in 2009. She took part in the development and clinical implementation of the first software for 3D myocardial deformation, working in an international team with colleagues from Belgium and Norway. Authored many scientific papers, holder of the Young Researcher award of the International Society of Hypertension in 2006, she has received honors from multiple national and international organizations.

Affiliations and Expertise

Associated Professor of Cardiology, National Heart Hospital, Sofia, Bulgaria

Galal Nagib Elkilany

Dr. Galal Eldin Nagib Elkilany received his BSc and MSc degrees from Tanta University, Egypt and his PhD & MD from the Post-Graduate Institute of Cardiology Department, Tanta University School of Medicine, Egypt. He was a Research Fellow in Thorax Center, Rotterdam, Holland, Erasmus University in Stress Echocardiography Department on 2000/2001. He is a Cardiology Specialist and Faculty in Tanta University Hospital from 1991 until 1998. He also worked as Consultant Cardiologist -degree of Professor of Cardiology 1998-2015, Cairo, Egypt- law No. 115. He is a Clinical Fellow in Milano-Majore Policlinico, Milan, Italy 2007 in cardiac cath. He is a Lab and Partner clinical Fellowship and visitor physician at University of Alabama, Birmingham, USA in 2011. He received a price of Young Investigator Award from Egyptian Society of Cardiology on 1999 & 2001. He has many famous international publications to his credit.

Affiliations and Expertise

Assistant Clinical Professor of Cardiology, Gulf Medical University, UAE

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