Paper and Thin Layer Chromatography

Paper and Thin Layer Chromatography

4th Edition - January 1, 1976

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  • Editors: Ivor Smith, J. W. T. Seakins
  • eBook ISBN: 9781483279923

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Chromatographic & Electrophoretic Techniques, Fourth Edition, Volume I: Paper and Thin Layer Chromatography presents the methods of paper and thin layer chromatography. This book discusses the practical approach in the application of paper and thin layer chromatography techniques in the biological sciences. Organized into 18 chapters, this edition begins with an overview of the clinical aspects related to the detection of those metabolic diseases that can result in serious illness presenting in infancy and early childhood. This text then discusses the three major types of screening for inherited metabolic disorders in which paper or thin-layer chromatography are being used, including screening the healthy newborn population, screening the sick hospitalized child, and screening mentally retarded patients. Other chapters consider the procedures for thin layer chromatography. This book discusses as well the complexity of amino acid mixtures present in natural products. The final chapter deals with the detection of synthetic basic drugs. This book is a valuable resource for chemists and toxicologists.

Table of Contents

  • Editors and Authors


    1. Introduction

    (a) The Early History of Chromatography

    (b) Introduction to Paper and Thin Layer Chromatography

    (c) Chromatography and Screening for Inborn Errors of Metabolism

    2. Paper Chromatographic Apparatus and Techniques

    3. Thin Layer Chromatography

    4. Sources of Error in Paper and Thin Layer Chromatography

    5. Aminoacids and Related Compounds

    Section 1. Techniques

    Section 2. Applications in Clinical Biochemistry

    6. Imidazoles

    7. Tryptophan Metabolites—TLC

    8. Purines, Pyrimidines and Related Compounds

    9. Sugars

    10. Phenolic Acids

    11. Ketoacids

    12. Organic Acids

    13. Steroids

    14. Lipids

    15. The Spark Chamber—A Technique for the Rapid Mapping of Radiochromatograms

    Toxicological Applications of Chromatography

    16. Part 1—Initial Screening and Tentative Identification of Drugs

    17. Part 2—Confirmation of Acidic and Neutral Drugs

    18. Part 3—Confirmation of Alkaloids and Basic Drugs


Product details

  • No. of pages: 476
  • Language: English
  • Copyright: © Butterworth-Heinemann 1976
  • Published: January 1, 1976
  • Imprint: Butterworth-Heinemann
  • eBook ISBN: 9781483279923

About the Editors

Ivor Smith

J. W. T. Seakins

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