Paper and Thin Layer Chromatography - 4th Edition - ISBN: 9780815178392, 9781483279923

Paper and Thin Layer Chromatography

4th Edition

Editors: Ivor Smith J. W. T. Seakins
eBook ISBN: 9781483279923
Imprint: Butterworth-Heinemann
Published Date: 1st January 1976
Page Count: 476
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Description

Chromatographic & Electrophoretic Techniques, Fourth Edition, Volume I: Paper and Thin Layer Chromatography presents the methods of paper and thin layer chromatography. This book discusses the practical approach in the application of paper and thin layer chromatography techniques in the biological sciences.

Organized into 18 chapters, this edition begins with an overview of the clinical aspects related to the detection of those metabolic diseases that can result in serious illness presenting in infancy and early childhood. This text then discusses the three major types of screening for inherited metabolic disorders in which paper or thin-layer chromatography are being used, including screening the healthy newborn population, screening the sick hospitalized child, and screening mentally retarded patients. Other chapters consider the procedures for thin layer chromatography. This book discusses as well the complexity of amino acid mixtures present in natural products. The final chapter deals with the detection of synthetic basic drugs.

This book is a valuable resource for chemists and toxicologists.

Table of Contents


Editors and Authors

Preface

1. Introduction

(a) The Early History of Chromatography

(b) Introduction to Paper and Thin Layer Chromatography

(c) Chromatography and Screening for Inborn Errors of Metabolism

2. Paper Chromatographic Apparatus and Techniques

3. Thin Layer Chromatography

4. Sources of Error in Paper and Thin Layer Chromatography

5. Aminoacids and Related Compounds

Section 1. Techniques

Section 2. Applications in Clinical Biochemistry

6. Imidazoles

7. Tryptophan Metabolites—TLC

8. Purines, Pyrimidines and Related Compounds

9. Sugars

10. Phenolic Acids

11. Ketoacids

12. Organic Acids

13. Steroids

14. Lipids

15. The Spark Chamber—A Technique for the Rapid Mapping of Radiochromatograms

Toxicological Applications of Chromatography

16. Part 1—Initial Screening and Tentative Identification of Drugs

17. Part 2—Confirmation of Acidic and Neutral Drugs

18. Part 3—Confirmation of Alkaloids and Basic Drugs

Index

Details

No. of pages:
476
Language:
English
Copyright:
© Butterworth-Heinemann 1976
Published:
Imprint:
Butterworth-Heinemann
eBook ISBN:
9781483279923

About the Editor

Ivor Smith

J. W. T. Seakins