Generation, Detection, and Characterization of Oxygen Radicals in Chemistry, Biochemistry, and Intermediate States of Reduction:
C. von Sonntag and H.-P. Schuchmann, Pulse Radiolysis.
M. Saran and W. Bors, Pulse Radiolysis for Investigation of Nitric Oxide-Related Reactions.
M. D'Aquino, C. Bullion, M. Chopra, D. Devi, S. Devi, C. Dunster, G. James, E. Komuro, E. Niki, F. Raza, F. Robertson, J. Sharma, and R. Willson, Sulfhydryl Free Radical Formation by Sonolysis, by Radiolysis, and Thermally: Vitamin A, Curcumin, Muconic Acid, and Related Conjugated Olefins and References.
C. von Sonntag and H.-P. Schuchmann, Suppression of Hydroxyl Radical Reactions in Biological Systems: Considerations Based on Competition Kinetics.
O.I Aruoma, Deoxyribose Assay for Detecting Hydroxyl Radicals.
H. Kaur and B. Halliwell, Detection of Hydroxyl Radicals by Aromatic Hydroxylation.
P.J. Evans and B. Halliwell, Measurement of Iron and Copper in Biological Systems: Blemycin and Copper-Phenanthroline Assays.
L.M. Weiner, Oxygen Radicals Generation and DNA Scission by Anticancer and Synthetic Quinones.
G.M. Rosen, S. Pou, B.E. Britigan, and M.S. Cohen, Spin Trapping of Hydroxyl Radicals in Biological Systems.
R.P. Mason and K.T. Knecht, In Vivo Detection of Radical Adducts by Electron Spin Resonance.
E. Albano, A. Tomasi, and M. Ingelman-Sundberg, Spin Trapping of Alcohol-Derived Radicals in Microsomes and Reconstituted Systemsby Electron Spin Resonance.
M. Tsuchiya, M. Suematsu, and H. Suzuki, In Vivo Visualization of Oxygen Radical-Dependent Photoemission.
J. Fuchs, N. Groth, T. Herrling, and L. Packer, In Vivo Electron Paramagnetic Resonance Imaging of Skin.
Since biological tissues are unstable in an oxygen atmosphere, a great deal of effort is expended by organisms to metabolically limit or repair oxidative tissue damage. This volume of Methods in Enzymology and its companion Volume 234 present methods developed to investigate the roles of oxygen radicals and antioxidants in disease.
@introbul:Key Features @bul: Generation, detection, and characterization of oxygen radicals, chemistry, biochemistry, and intermediate states of reductio Isolation, characterization, and assay of enzymes or substrates involved in formation or removal of oxygen radical
- Methods for assessing molecular, cell, and tissue damage; assays and repair of oxidative damage
Biochemists, pharmacologists, physiologists, and cell biologists.
- No. of pages:
- © Academic Press 1994
- 22nd March 1994
- Academic Press
- eBook ISBN:
- Hardcover ISBN:
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California Institute of Technology, Division of Biology, Pasadena, U.S.A.
The Salk Institute, La Jolla, CA, USA
Helmut Sies is an Honorary Member of the American Society for Biochemistry and Molecular Biology. He received an Honorary Ph.D. from the University of Buenos Aires, Argentina in 1996. Dr. Sies is a member of the Northrhine-Westphalian Academy of Sciences, Germany, and a Corresponding Member of both the Academy of Sciences of Heidelberg, Germany, and the Academy of Medicine, Buenos Aires, Argentina. He has received many awards and prizes, including the FEBS Anniversary Prize awarded by the Federation of European Biochemical Societies, 1978; the Distinguished Foreign Scholar award, MASUA, 1985; the Silver Medal, Karolinska Institute, Stockholm, 1986; the Ernst Jung Preis fur Medizin, 1988; the Claudius-Galenus-Preis, 1990; and the ISFE-Preis, 1994. Dr. Sies sereves on the editorial board and advisory committee for twelve journals, has edited numerous books, and has published more than 400 original articles and chapters. He received his M.D. at the University of Munich in 1967 and currently serves as Full Professor and Chairman of the Department of Physiological Chemistry at the University of Düsseldorf.
Institut Fur Physiologische Chemie, Germany