Secure CheckoutPersonal information is secured with SSL technology.
Free ShippingFree global shipping
No minimum order.
Section I. Hypoxia-inducible factor
HIF PAS domains: structure and function
Thomas H. Scheuermann, Jinsong Yang, Lei Zhang, Kevin H. Gardner, and Richard K. Bruick
Structure-function analysis of HIF
HIF Prolyl Hydroxylase: Purification and Assays of PHD2
Kirsty S. Hewitson, Christopher J. Schofield, Peter J. Ratcliffe
Determination and modulation of prolyl-4-hydroxylase domain (PHD) oxygen sensor activity
Renato Wirthner, Kuppusamy Balamurugan, Daniel P. Stiehl, Sandra Barth, Patrick Spielmann, Felix Oehme, Ingo Flamme, Dörthe M. Katschinski, Roland H. Wenger and Gieri Camenisch
Characterisation of ankyrin-repeat containing proteins as substrates of the asparaginyl hydroxylase Factor Inhibiting HIF (FIH-1).
Sarah Linke, Rachel J. Hampton-Smith, Daniel J. Peet
Transgenic Models to Understand HIF Function
Andrew Doedens and Randall S. Johnson
The Silencing Approach of the Hypoxia Signalling Pathway"
Edurne Berra and Jacques Pouyssegur
Cellular and developmental adaptations to hypoxia; a Drosophila perspective
Nuria Magdalena Romero, Andrés Dekanty, Pablo Wappner
Section II. Erythropoietin
Constitutively overexpressed erythropoietin reduces infarct size in a mouse model of permanent coronary artery ligation
Giovanni G. Camici, Thomas Stallmach, Matthias Hermann, Rutger Hassink, Peter Doevendans, Beat Grenacher, Alain Hirschy, Johannes Vogel, Thomas F. Lüscher, Frank Ruschitzka and Max Gassmann
Control of erythropoietin gene expression and its use in medicine
Role of HIF-2 in endothelial development and hematopoiesis
Osamu Ohneda1,3, Masumi Nagano1,3 and Yoshiaki Fujii-Kuriyama
Section III. Hypoxia and adaptation
ORGAN PROTECTION BY HYPOXIA AND HIF
Wanja M. Bernhardt, Christina Warnecke, Carsten Willam, Michael S. Wiesener and
Hypoxia and regulation of mRNA translation
Marianne Koritzinsky and Bradly G. Wouters
Hypoxia and the Unfolded Protein Response
Constantinos Koumenis, Meixia Bi, Jiangbin Ye, Douglas Feldman and Albert C. Koong
Section IV. Hypoxia and tumor biology
Tumor hypoxia in cancer therapy
J. Martin Brown
HIF Gene Expression in Cancer Therapy
By Denise A. Chan, Adam J. Krieg, Sandra Turcotte, and Amato J. Giaccia
Analysis of HIF-1 Expression and Its Effects on Invasion and Metastasis
Balaji Krishnamachary, Gregg L. Semenza
Macrophage migration inhibitory factor (MIF) manipulation and evaluation in tumoral hypoxic adaptation
Millicent Winner, Lin Leng, Wayne Zundel and Robert A. Mitchell
The von Hippel-Lindau Tumor Suppressor Protein: An Update
William G. Kaelin, Jr.
Hypoxia Inducible Factor 1 (HIF-1) inhibitors
Section V. Hypoxia and inflammatory mediators
Regulation of HIF during Inflammation
Stilla Frede, Utta Berchner-Pfannschmidt, Joachim Fandrey
Superoxide and derived reactive oxygen species in the regulation of hypoxia-inducible factors
Agnes Görlach, Thomas Kietzmann
Genetics of mitochondrial electron transport chain in regulating oxygen sensing
Eric L. Bell and Navdeep S. Chandel
Hypoxia inducible factor-1 (HIF-1) under the control of nitric oxide (NO)
Bernhard Brüne and Jie Zhou
Hypoxic regulation of NF-κB signalling
Eoin P. Cummins, Katrina M. Comerford, Carsten Scholz, Ulrike Bruning & Cormac T. Taylor
For over fifty years the Methods in Enzymology series has been the critically acclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume features articles on the topic of oxygen biology and hypoxia.
Biochemists and researchers in related life science disciplines.
- No. of pages:
- © Academic Press 2007
- 8th November 2007
- Academic Press
- Hardcover ISBN:
- eBook ISBN:
Helmut Sies, MD, PhD (hon), studied medicine at the universities of Tübingen, Munich, and Paris. He was the professor and chair of the Institute for Biochemistry and Molecular Biology I at Heinrich-Heine-University Düsseldorf, Germany, where he is now professor emeritus. He is a member of the German National Academy of Sciences Leopoldina and was the president of the North Rhine-Westphalian Academy of Sciences and Arts. He was named ‘Redox Pioneer’; was the president of the Society for Free Radical Research International (SFRRI). Helmut Sies introduced the concept of “Oxidative Stress” in 1985, and was the first to reveal hydrogen peroxide as a normal constituent of aerobic cell metabolism. His research interests comprise redox biology, oxidants, antioxidants, micronutrients.
Heinrich-Heine-University Düsseldorf, Germany
Elsevier.com visitor survey
We are always looking for ways to improve customer experience on Elsevier.com.
We would like to ask you for a moment of your time to fill in a short questionnaire, at the end of your visit.
If you decide to participate, a new browser tab will open so you can complete the survey after you have completed your visit to this website.
Thanks in advance for your time.