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Oxidative Stress
Its Mechanisms and Impacts on Human Health and Disease Onset
- 1st Edition - October 23, 2022
- Author: Harold Zeliger
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 1 8 9 0 - 9
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 1 4 5 8 - 1
Oxidative Stress: Its Impact on Human Health and Disease Onset examines all factors known to elevate oxidative stress (OS) and the mechanism of OS disease causation… Read more
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Request a sales quoteOxidative Stress: Its Impact on Human Health and Disease Onset examines all factors known to elevate oxidative stress (OS) and the mechanism of OS disease causation. Sections cover the causes and prevention of oxidative stress, the types of chemical exposures and environmental factors that precipitate disease, disease hallmarks and biomarkers, disease clusters, disease co-morbidities, free radical attacks at the cellular level, and the Oxidative Stress Index tool, its premise, and how it can be used to identify the primary causes of specific diseases and predict the likelihood of disease onset.
With comprehensive coverage of not only the impact of OS due to chemical exposure but also the consequences of environmental factors, this book is a valuable resource for researchers and scientists in toxicology and environmental science, health practitioners, public health professionals, and others who wish to broaden their knowledge on this topic.
- Covers the chemical exposures and environmental factors that cause oxidative stress
- Provides further understanding on the mechanisms of oxidative damage response and disease
- Shows how oxidative stress and its role can be determined non-invasively via the Oxidative Stress Index
Researchers, toxicologists-particularly those engaged in mechanistic research, clinicians, academics, public health officials; industrial hygienists, chemical manufacturers and those responsible for workplace safety
Dedication
Preface
I. OXIDATIVE STRESS AND DISEASE
1. Introduction
2. Chemicals and chemical mixtures
3. Particles and fibers
4. Air pollution
5. Water and soil pollution
6. Alcohol
7. Tobacco
8. Electromagnetic Radiation
9. Inflammation
10. Food
11. Sleep deprivation
12. Pharmaceuticals
13. Psychological stress
14. Genetics and epigenetics
15. Aging
16. Diseases and co-morbidities
17. Total oxidative stress and disease
18. Free radicals
II. MECHANISMS OF OXIDATIVE STRESS DRIVEN DISEASE
19. Aging mechanism
20. Obesity
21. Cancer
22. Atherosclerosis
23. Alzheimer’s disease
24. Type 2 diabetes
25. Rheumatoid arthritis
26. Asthma
27. Liver cirrhosis
28. Chronic kidney disease
29. Co-morbidities
III. DISEASE ONSET PREDICTION
30. Oxidative stress index
31. Condensed oxidative stress index
32. Oxidative stress index and Alzheimer’s disease
33. Oxidative stress index and public health surveys
34. Oxidative stress index and predicting COVID-19 severity
IV. PREVENTION
35. Lowering oxidative stress
36. Global warming and disease
- No. of pages: 500
- Language: English
- Edition: 1
- Published: October 23, 2022
- Imprint: Academic Press
- Paperback ISBN: 9780323918909
- eBook ISBN: 9780323914581
HZ
Harold Zeliger
Dr. Harold I. Zeliger holds a PhD in organic chemistry and has been a professor of chemistry and environmental science. He is a Certified Professional Chemist, a Board- Certified Forensic Examiner, and an EPA Certified Laboratory Director. Dr. Zeliger is the author of 51 technical publications, including basic research journal articles and patents. In his more than 40 years in the Chemical Process Industry, he has personally developed many industrial and consumer chemical products, designed chemical product warning labels and written Material Safety Data Sheets for toxic and flammable chemicals. Dr. Zeliger has investigated hundreds of toxic chemical exposures, environmental spills and discharges, chemical fires and explosions nationally and internationally. He has served repeatedly as an expert witness for both plaintiffs and defendants in chemical product, process, toxic exposure, environmental, flammable, intellectual property and subrogation claims. Dr. Zeliger has provided services for numerous forensic examinations, technology transfer and due diligence investigations. Dr. Zeliger’s research is in the area of chemical toxicology. His published work includes papers on the toxic effects of chemical mixtures and chemical causes of cancer clusters and two editions of Human Toxicology of Chemical Mixtures, Second Edition.
Affiliations and expertise
Toxic and Flammable Chemical Consultant and Expert Witness; Certified Professional Chemist and Board Certified Forensic Examiner; Technology Transfer and Due Diligence Investigator, USARead Oxidative Stress on ScienceDirect