Osteoporosis in Men

2nd Edition

The Effects of Gender on Skeletal Health

Editors: Eric Orwoll John Bilezikian Dirk Vanderschueren
Hardcover ISBN: 9780123746023
eBook ISBN: 9780080923468
Imprint: Academic Press
Published Date: 17th November 2009
Page Count: 741
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Since the publication of the first edition, the U.S. Surgeon General released the first-ever report on bone health and osteoporosis in October 2004. This report focuses even more attention on the devastating impact osteoporosis has on millions of lives. According to the National Osteoporosis Foundation, 2 million American men have osteoporosis, and another 12 million are at risk for this disease. Yet despite the large number of men affected, the lack of awareness by doctors and their patients puts men at a higher risk that the condition may go undiagnosed and untreated. It is estimated that one-fifth to one-third of all hip fractures occur in men.

This second edition brings on board John Bilezikian and Dirk Vanderschueren as editors with Eric Orwoll. The table of contents is more than doubling with 58 planned chapters. The format is larger – 8.5 x 11. This edition  of Osteoporosis in Men brings together even more eminent investigators and clinicians to interpret developments in this growing field, and describe state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy.

Key Features

  • Brings together more eminent investigators and clinicians to interpret developments in this growing field.
  • Describes state-of-the-art research as well as practical approaches to diagnosis, prevention and therapy.
  • There is no book on the market that covers osteoporosis in men as comprehensively as this book.


Academic, medical, and pharmaceutical researchers in bone biology, endocrinology, and rheumatology; Medical researchers in pediatrics, internal medicine, orthopedics, primary care, geriatrics, obstetrics and gynecology, oncology, and nephrology.

Table of Contents

Section 1 – Essentials of bone biology

  1. The Biochemistry of Bone: Composition and Organization
  2. Adele L. Boskey

  3. Bone Remodeling: Cellular Activities in Bone
  4. David W. Dempster, Hua Zhou, Shi Shou Lu

  5. Assessment of Bone Turnover Using Biochemical Markers
  6. Patrick Garnero, Pawel Szulc

  7. Fundamentals of Mineral Homeostasis
  8. David A. Hanley, Shawn K. Davison

  9. The Mechanical Properties of Bone
  10. David P. Fyhrie

  11. Assessment of Bone Architecture
  12. Thomas F. Lang


    Section 2 – Development and growth of the male skeleton

  13. Skeletal Growth in Males
  14. Qingju Wang, Ego Seeman

  15. Pubertal Growth of the Male Skeleton
  16. Vincent Gilsanz, Stefano Mora

  17. The Effects of Sex Steroids on Bone Growth
  18. Giampiero I. Baroncelli, Silvano Bertelloni

  19. Nutritional Basis of Skeletal Growth
  20. Connie M. Weaver, Elizabeth Haney

  21. Physical Activity and Skeletal Growth
  22. Heather M. Macdonald, Heather A. McKay, Melonie Burrows


    Section 3 – Skeletal genetics

  23. The Genetics of Peak Bone Mass
  24. Luigi Gennari, Robert F. Klein, Serge Ferrari

    Section 4 – Aging and the male skeleton

  25. Age-Related Changes in Bone Remodeling and Micro Architecture
  26. Roger Zebaze, Ego Seeman

  27. Markers of Bone Remodeling and the Aging Skeleton
  28. Serge Cremers, Christian Meier, Markus J. Seibel

  29. Alterations in Mineral Metabolism in the Aging Male
  30. Shonni J. Silverberg, Bismruta Misra

  31. Change in Bone Size and Geometry with Aging
  32. <


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About the Editor

Eric Orwoll

Professor of Medicine and Director, Clinical Research Center, Division of Endocrinology, Diabetes and Clinical Nutrition, Oregon Health & Science University, Portland, Oregon

Affiliations and Expertise

Oregon Health Sciences University, Portland, Oregon, USA

John Bilezikian

John P. Bilezikian, MD, the Dorothy L. and Daniel H. Silberberg Professor of Medicine and Professor of Pharmacology at the College of Physicians & Surgeons, Columbia University is Chief of the Division of Endocrinology and Director of the Metabolic Bone Diseases Program at Columbia University Medical Center. Dr. Bilezikian received his undergraduate training at Harvard College and his medical training at the College of Physicians & Surgeons. He completed four years of house staff training (internship, residency and Chief Residency) on the Medical Service at Columbia Presbyterian Medical Center. Dr. Bilezikian received his training in Metabolic Bone Diseases and in Endocrinology at the NIH in the Mineral Metabolism Branch under the tutelage of Dr. Gerald Aurbach. Dr. Bilezikian belongs to a number of professional societies including the American Society for Bone and Mineral Research, of which he served as President, 1995-1996 and the International Society of Clinical Densitometry, of which he served as President, 1999-2001. He serves on the Board of Governors of the International Osteoporosis Foundation (1998-present) and on its Committee of Scientific Advisors (2001-present). He is Chair of the Endocrine Fellows Foundation. He served as Editor-in-Chief of the Journal of Clinical Endocrinology and Metabolism (2000-2004) and as Senior Associate Editor of the Journal of Bone and Mineral Research (2008-2012). He is Executive Advisory Editor of Bone Research (2013-present). His books include Editor-in-Chief of The Parathyroids [1994, 2001, 2014], and co-editor of The Aging Skeleton (1999), Dynamics of Bone and Cartilage Metabolism (1999, 2006), Principles of Bone Biology (1996, 2002, 2008) and Osteoporosis in Men (2010). He served as co-chair of the last three NIH Workshops on Primary Hyperparathyroidism (2002, 2008, 2013). He is the recipient of the Distinguished Physician Award of the Endocrine Society, the Frederic C. Bartter Award of the American Society for Bone and

Affiliations and Expertise

Columbia University, New York, New York, U.S.A.

Dirk Vanderschueren

Professor of Medicine, Division of Endocrinology, Department of Internal Medicine, UZ Gasthuisberg, Leuven, Belgium

Affiliations and Expertise

UZ Gasthuisberg, Leuven, Belgium


"The editors of Osteoporosis in Men, Second Edition have produced a comprehensive compendium about osteoporosis as it relates to men. An established group of experts has contributed to the second edition of this excellent book. The topics range from the basics of osteoporosis to sections on growth of the skeleton, aging, importance of nutrition, sex hormones, and the development of the disorder. Key sections of clinical relevance including diagnosis and treatment of osteoporosis in men are covered in depth. This book will serve as an excellent resource for established clinicians and investigators as well as for students and fellows."

--Richard Eastell, MD, FRCP, FRCPath, FMedSci, Professor of Bone Metabolism, Director of the NIHR Bone Biomedical Research Unit, Centre for Biomedical Research, Northern General Hospital, Sheffield, South Yorkshire, United Kingdom

"The 10 sections and total of 57 informative chapters in the second edition of the text Osteoporosis in Men constitute an impressive body of up-to-date information by leading experts on this important topic. The text is particularly useful because of its breadth extending from basic bone biology and environmental factors affecting skeletal development in men to clinical chapters on pathophysiology, diagnosis, and therapy. The editors have provided a comprehensive yet practical approach to the topic which makes the text useful to a broad potential audience ranging from trainees to established leaders in the field."

-- John T. Potts, Jr., MD, Director of Research and Physician-in-Chief emeritus, Massachusetts General Hospital, Jackson Distinguished Professor of Clinical Medicine, Harvard Medical School, Boston, MA, USA

"This thorough and comprehensive book integrates new, accessible, and informative material in the field. It will help investigators, as well as practitioners and students, to improve their understanding of male skeletal health and male skeletal loss. The addition