Key Features

  • Features the work of leading experts in osteoarthritis.
  • Presents current diagnostic criteria and knowledge of pathogenic mechanisms.
  • Discusses the very latest advances in treatment, including pharmacologic interventions.
  • Provides new concepts in epidemiology and genetics of osteoarthritis, including modifiable and non-modifiable risk factors.

Table of Contents

EPIDEMIOLOGY

1. Epidemiology of OA

PATHOGENESIS

2. Role of bone in OA

3. Impact of Mechanical Stress on the Pathophysiology of OA

4. Update on the Chondrocyte Lineage and Implication for Cell Therapy in OA

5. Aging Cartilage and OA Cartilage: Differences and Shared Mechanisms

6. Role of Adipocytokines in OA

7. Novel Experimental Models for the Study of OA

8. Signaling Transduction: Targets in OA

CLINICAL ASPECTS

9. Biomarkers, Evidence for Promising Markers

10. Update on Radiographic Imaging

11. Update on MRI in OA

TREATMENT

12. Update on COX-2 Inhibitors, Non-selective NSAIDs, and ASA Co-therapy

13. Alternative Therapies in OA

14. Novel Physical Therapy Approaches to Enhance Muscle Activity and Minimize Instability in OA

15. Disease-Modifying Drugs in OA

16. Nutritional Supplements in the Treatment of OA

Details

No. of pages:
296
Language:
English
Copyright:
© 2007
Published:
Imprint:
Mosby
Print ISBN:
9780323039291
Electronic ISBN:
9780323070645