Osseointegration of Orthopaedic Implants

Osseointegration of Orthopaedic Implants

1st Edition - March 16, 2019

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  • Author: Amirhossein Goharian
  • Paperback ISBN: 9780128133842
  • eBook ISBN: 9780128133958

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Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons.

Key Features

  • Reviews and discusses all aspects of orthopedic implant osseointegration
  • Provides conceptual implants for bone fracture fixation and joint replacement
  • Offers novel ideas for the development of orthopedic implants with superior osseointegration


Product Developers at orthopaedic implant manufacturers, Biomechanical researchers, Biomaterial researchers, Biomedical engineering lecturers and students, Medical implants institutes

Table of Contents

  • Part I General topics in osteointegration
    1. Biology of bone tissue
    2. History of osteointegration
    3. Basic science research and clinical findings of osteointegration

    Part II Overview of orthopedic implants
    4. Implant loosening
    5. Bone fracture fixation implants
    6. Joint replacement prostheses
    7. Tissue engineering scaffolds

    Part III Biomaterials for enhancement of osteointegration
    8. Osteoconductive materials
    9. Osteoinductive materials
    10. Bioactive materials

    Part IV Surface treatments for enhancement of osteointegration
    11. Bioactive coating
    12. Porous surface
    13. Surface treatment

    Part V Biological concepts and challenges of osteointegration
    14. Bone tissue in-growth and on-growth
    15. Body fluid rate effect on osteointegration
    16. Osteoinductivity and Osteoconductivity

    Part VI Mechanical concepts and challenges of osteointegration
    17. Load transferring mechanism between bone and implant
    18. Osteointegration in long term implantation
    19. Stress shielding effect on osteointegration
    20. Biomechanical concepts of scaffolding

    Part VII Novel development concepts
    21. Novel development concepts of implant osteointegration
    22. Transition layer concept
    23. Improvement of long term bioactivity at transition layer
    24. Enhancement of load transferring at transition layer
    25. Development of shape memory concept at transition layer
    26. Promoting osteointegration of physiological loading cycles at early implantation

Product details

  • No. of pages: 210
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: March 16, 2019
  • Imprint: Academic Press
  • Paperback ISBN: 9780128133842
  • eBook ISBN: 9780128133958

About the Author

Amirhossein Goharian

Amirhossein Goharian is a Senior Engineer working in the orthopedic implant industry. He earned his Bachelor’s degree from the University of Kashan in 2007, and his completed his Master’s in Mechanical Engineering in Biomechanics at the University Technology Malaysia (UTM) in 2012. He joined the R&D department of LEONIX Sdn. Bhd., Penang, Malaysia, in 2012, rising to Senior R&D Leader in Jan 2015. In 2017, he joined Isfahan Orthopedic Implant Development Co., an orthopedic implant manufacturer in Isfahan, Iran, as the QA-R&D leader until Sep 2020. Since then, he has been developing innovations in the field of orthopedic implants, based on ideas set out in his published work. Goharian has previously published three books with Elsevier, covering trauma plating systems, osseointegration and surface engineering of orthopedic implants.

Affiliations and Expertise

Independent Engineering Consultant in Orthopaedic Implant and Biomaterial Industry, Isfahan, Iran

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