Description

This volume pulls together a wealth of up-to-date information on the toxicology of this diverse and ubiquitous class of insecticides. Leading experts review the reactivity of organophosphorus compounds with cholinesterase, as well as their metabolism and biological effects on humans and other nontarget organisms. The book not only covers the anticholinesterase actions of organophosphates, but also other, presumably independent, effects, such as teratogenicity, delayed neuropathy, immunotoxicity, and behavioral toxicity.

Key Features

  • Offers crucial overviews of chemical and biochemical reactivity and biological responsiveness of mainly nontarget organisms
  • Reviews new developments in assessment of metabolism and disposition of organophosphorus compounds
  • Examines organophosphorus compound-induced toxicity mediated by mechanisms other than
    inhibition of acetylcholinesterase
  • Covers new research on differences in toxicity induced by the variety of organophosphorus
  • Analyzes current controversies on the relevance of certain biochemical parameters in actual organophosphate toxicity in vivo

Readership

Toxicologists, pesticide chemists, environmental scientists, public health specialists, and pharmacologists

Table of Contents

(Section Headings): Introduction. Metabolic Fate. Toxic Effects--Noncholinergic Biochemical. Toxic Effects--Organismal. Summary and Conclusions.

Details

No. of pages:
440
Language:
English
Copyright:
© 1992
Published:
Imprint:
Academic Press
eBook ISBN:
9780080917269
Print ISBN:
9780121673451

About the editors

Janice Chambers

Affiliations and Expertise

Mississippi State University, U.S.A.

Patricia Levi

Affiliations and Expertise

North Carolina State University, Raleigh, U.S.A.