Organolithiums: Selectivity for Synthesis

Organolithiums: Selectivity for Synthesis

1st Edition - July 12, 2002

Write a review

  • Author: J Clayden
  • Paperback ISBN: 9780080432618

Purchase options

Purchase options
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order


This volume, number 23 in the "Tetrahedron Organic Chemistry" series, presents organolithium chemistry from the perspective of a synthetic organic chemist, drawing from the synthetic literature to present a unified overview of how organolithiums can be used to make molecules. The development of methods for the regioselective synthesis of organolithiums has replaced their image of indiscriminate high reactivity with one of controllable and subtle selectivity. Organolithium chemistry has a central role in the selective construction of C-C bonds in both simple and complex molecules, and for example has arguably overtaken aromatic electrophilic substitution as the most powerful method for regioselective functionalisation of aromatic rings. The twin themes of reactivity and selectivity run through the book, which reviews the ways by which organolithiums may be formed and the ways in which they react. Topics include advances in directed metallation, reductive lithiation and organolithium cyclisation reactions, along with a discussion of organolithium stereochemistry and the role played by ligands such as (-)-sparteine.

Product details

  • No. of pages: 400
  • Language: English
  • Copyright: © Pergamon 2002
  • Published: July 12, 2002
  • Imprint: Pergamon
  • Paperback ISBN: 9780080432618

About the Author

J Clayden

Affiliations and Expertise

Department of Chemistry University of Manchester Manchester UK

Ratings and Reviews

Write a review

There are currently no reviews for "Organolithiums: Selectivity for Synthesis"