Organofluorine Chemistry

Organofluorine Chemistry

Synthesis and Applications

1st Edition - March 20, 2020

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  • Author: V. Prakash Reddy
  • eBook ISBN: 9780128132876
  • Paperback ISBN: 9780128132869

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Organofluorine Chemistry: Synthesis and Applications gives a comprehensive outlook on modern synthetic methodologies for organofluorine compounds. It illustrates chemical, biochemical, and materials applications of fluorine-containing compounds, including synthesis and applications of small molecule compounds in drug discovery, positron emission tomography, and fluorinated polymers in solar cells. This book is of use to scientists working in the interdisciplinary areas, such as chemical, biochemical, and biomedical engineering, as well as those involved in materials science and medicinal chemistry. It is also a useful reference for researchers and graduate students interested in organofluorine chemistry.

Key Features

  • Provides modern synthetic methods and reactions of organofluorine compounds
  • Incorporates the synthesis and chemical, biochemical and biomedical applications of fluorine-containing compounds, nanomaterials, PET imaging agents, pharmaceuticals, and polymeric materials
  • Features emerging "hot" topics, such as late-stage fluorinations and drug discovery


Organofluorine chemists, especially for those in interdisciplinary areas in chemical-, biochemical-, and biomedical engineering, materials science, and medicinal chemistry. Academic researchers and industrial scientists interested in synthetic and interdisciplinary aspects of fluorine chemistry. Advanced level graduate/senior undergraduate courses in organofluorine chemistry

Table of Contents

  • 1. Nucleophilic Fluorination and Fluoroalkylation
    2. Electrophilic Fluorination and Fluoroalkylation
    3. Free-radical Fluoroalkylation
    4. Organotransition Metal Catalysis in Fluorinations and Fluoroalkylations
    5. Pharmaceutical Applications of Organofluorine compounds
    6. Synthesis and Applications of 18F-Labeled Compounds
    7. Materials Applications of Organofluorine compounds

Product details

  • No. of pages: 358
  • Language: English
  • Copyright: © Elsevier 2020
  • Published: March 20, 2020
  • Imprint: Elsevier
  • eBook ISBN: 9780128132876
  • Paperback ISBN: 9780128132869

About the Author

V. Prakash Reddy

Dr. V. Prakash Reddy is currently a professor of chemistry at the Missouri University of Science and Technology, United States. He received the Golden Key National Honor Society award for teaching excellence at Case Western Reserve University, and was also a NASA faculty fellow at the Jet Propulsion Laboratory, Pasadena, California. His research interests are in the cutting-edge interdisciplinary areas of synthetic and mechanistic organic- and bio-organic chemistry, drug discovery toward neuronal disorders and other age-related diseases, carbocations, electrophilic reactions, superacids, and organofluorine chemistry. He has published over 100 peer-reviewed articles, book chapters, and patent disclosures, and is also the author of the book Organofluorine Compounds in Biology and Medicine, published by Elsevier.

Affiliations and Expertise

Missouri University of Science and Technology, MO, United States

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