Description

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

Key Features

Covers reviews of methodology and research in all aspects of protein chemistry.
Brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics.

Readership

Biochemists, biophysicists, cell biologists, protein chemists, structural geneticists, and structural biologists

Table of Contents

Preface

Chapter One. Large Tandem Repeats Make up the Chromosome Bar Code: A Hypothesis

1 Introduction

2 Satellite DNA in the Mouse Genome

3 Tandem Repeat Position Defined by FISH

4 “Bar Code” Hypothesis

Chapter Two. Mammalian Satellite DNA: A Speaking Dumb

1 Introduction

2 Heterochromatin Criteria

3 The Constitutive HC DNA

4 Transcription of HC DNA

5 Functions of Centromeric and Pericentromeric HC DNA Transcription

6 Conclusions

Chapter Three. Zinc Finger Proteins and the 3D Organization of Chromosomes

1 The 3D Organization of the Genome and Loops

2 CTCF and its Role in the 3D Genome Organization

3 A Model for CTCF

4 A Model for CTCF Binding

5 A Method to Compute Similarity for Unstructured Proteins

6 Discussion and Outlook

Chapter Four. Dynamics of Modeled Oligonucleosomes and the Role of Histone Variant Proteins in Nucleosome Organization

1 Introduction

2 Role of H2A.Z in the Dynamics of Modeled Oligonucleosomes

3 Conclusions and Outlook

Chapter Five. Unconventional Actin Configurations Step into the Limelight

1 Introduction

2 Structural Organization of Actin

3 Tools to Study Actin Localization, Arrangement, and Conformation

4 There is More Than F- and G-Actin in Eukaryotic Cells

5 Unconventional Actin Contacts

6 Conclusion

Chapter Six. Chromatin Reorganization Through Mitosis

1 Packaging the Genome

2 The Mitotic Chromosome

3 Specialized Mitotic Chromatin

4 Gene Bookmarking

5 Going Back to Interphase: Chromosome Decondensation

Author Index

Subject Index

Details

No. of pages:
264
Language:
English
Copyright:
© 2013
Published:
Imprint:
Academic Press
Print ISBN:
9780124105232
Electronic ISBN:
9780124105447

Reviews

"The authority, originality, and editing of the reviews are first class." -- NATURE