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Organic Chemistry - 2nd Edition - ISBN: 9780128128381, 9780128128398

Organic Chemistry

2nd Edition

Structure, Mechanism, Synthesis

Authors: J. David Rawn Robert Ouellette
Hardcover ISBN: 9780128128381
eBook ISBN: 9780128128398
Imprint: Academic Press
Published Date: 9th January 2018
Page Count: 1056
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Organic Chemistry: Structure, Mechanism, Synthesis, Second Edition, provides basic principles of this fascinating and challenging science, which lies at the interface of physical and biological sciences. Offering accessible language and engaging examples and illustrations, this valuable introduction for the in-depth chemistry course engages students and gives future and new scientists a new approach to understanding, rather than merely memorizing the key concepts underpinning this fundamental area. The book builds in a logical way from chemical bonding to resulting molecular structures, to the corresponding physical, chemical and biological properties of those molecules.

The book explores how molecular structure determines reaction mechanisms, from the smallest to the largest molecules—which in turn determine strategies for organic synthesis. The book then describes the synthetic principles which extend to every aspect of synthesis, from drug design to the methods cells employ to synthesize the molecules of which they are made. These relationships form a continuous narrative throughout the book, in which principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the theory and applications.

Featuring in-book solutions and instructor PowerPoint slides, this Second Edition offers an updated and improved option for students in the two-semester course and for scientists who require a high quality introduction or refresher in the subject.

Key Features

  • Offers improvements for the two-semester course sequence and valuable updates including two new chapters on lipids and nucleic acids
  • Features biochemistry and biological examples highlighted throughout the book, making the information relevant and engaging to readers of all backgrounds and interests
  • Includes a valuable and highly-praised chapter on organometallic chemistry not found in other standard references


Advanced students (in the 2-semester course). Secondary interest seen in early career researchers and others requiring foundational info

Table of Contents

1. Structure and Bonding in Organic Compounds
2. Functional Groups and Their Properties
3. Introduction to Organic Reaction Mechanisms
4. Alkanes and Cycloalkanes: Structures and Reactions
5. Stereochemistry
6. Alkenes Structures and Properties
7. Alkenes: Addition Reactions
8. Alkynes
9. Haloalkanes and Alcohols: Introduction to Nucleophilic Substitution and Elimination Reactions
10. Nucleophilic Substitution and Elimination Reactions
11. Conjugated Alkenes and Allylic Systems
12. Arenes and Aromaticity
13. Electrophilic Aromatic Substitution
14. Methods for Structure Determination Nuclear Magnetic Resonance and Mass Spectrometry
15. Alcohols: Reactions and Synthesis
16. Ethers and Epoxides
17. Aldehydes and Ketones
18. Aldehydes and Ketones: Nucleophilic Addition Reactions
19. Carboxylic Acids
20. Carboxylic Acid Derivatives
21. Condensation Reactions of Carbonyl Compounds
22. Amines and Amides
23. Aryl Halides, Phenols, and Anilines
24. Organometallic Chemistry of Transition Metal Elements and Introduction to Retrosynthesis
25. Pericyclic Reactions
26. Carbohydrates
27. Amino Acids, Peptides, and Proteins
28. Synthetic Polymers


No. of pages:
© Academic Press 2019
9th January 2018
Academic Press
Hardcover ISBN:
eBook ISBN:

About the Authors

J. David Rawn

J. David Rawn, Department of Chemistry, Towson University

Affiliations and Expertise

Towson University, Baltimore, MD, USA

Robert Ouellette

Robert J. Ouellette, Professor Emeritus, Department of Chemistry, The Ohio State University.

Affiliations and Expertise

Emeritus Professor, The Ohio State University, Columbus, OH, USA

Ratings and Reviews