Description

The field of nuclear magnetic resonance spectroscopy has undergone explosive development during the last decade with the advent of new one- and two-dimensional techniques. The author has had extensive experience in the use of these techniques for the structure elucidation of complex natural products, and in this book he gives a comprehensive, up-to-date and very readable account of these developments.

The book's scope is very wide. It starts from fundamental principles of modern NMR spectroscopy, describing the instrumentation and its optimum use, and extends to the latest developments such as inverse measurements. Emphasis is on problem-solving so as to be useful to a large number of organic chemists, biochemists and medicinal chemists. The problems and worked solutions at the end of the chapters will help students to gain proficiency in the application of these new techniques. Those who are learning how to operate modern NMR spectrometers will find particularly useful the description of such basic aspects as shimming, probe tuning, and methods for improvement of resolution and sensitivity.

Table of Contents

Foreword (Lloyd M. Jackman). 1. Basic Principles of Modern NMR Spectroscopy. 2. Spin-Echo and Polarisation Transfer. 3. Carbon-Carbon Connectivity - 1D Inadequate Spectra. 4. The Nuclear Overhauser Effect. 5. Two-Dimensional NMR Spectroscopy - Basic Principles. 6. Heteronuclear 2D J-Resolved Spectroscopy. 7. Homonuclear 2D J-Resolved Spectroscopy. 8. Homonuclear 2D Shift Correlated Spectroscopy. 9. Chemical Shift Correlation Through Cross-Relaxation and Exchange. 10. Heteronuclear 2D-Shift Correlation Spectroscopy. 11. Cross Polarisation in the Rotating Frame. 12. 2D Multiple-Quantum Spectroscopy. 13. Tackling the Structure. 14. Product Operator Approach to 2D-NMR Spectroscopy. Appendix 1. Some Terms, Symbols and Acronyms used in NMR Spectroscopy. Appendix 2. Summary of Important 2D NMR Techniques. Index.

Details

Language:
English
Copyright:
© 1989
Published:
Imprint:
Elsevier Science
Electronic ISBN:
9781483290713
Print ISBN:
9780444873163

About the author

Atta-ur- Rahman

Atta-ur-Rahman, FRS, D.Phil., TI, SI HI, NI, is a leading scientist and scholar in the field of organic chemistry from Pakistan, especially renowned for his research in the various areas relating to natural product chemistry. With over 909 publications in the field of his expertise including 116 books largely published by leading publishers in Europe and USA and 27 patents, he is also credited for reviving the higher education and research practices in Pakistan. Prof. Rahman was elected as Fellow of Royal Society (London) in July 2006 thereby becoming one of the 4 scientists from the Muslim world to have ever won this honor in the last 350 years when the Royal Society was established. He is also the only scientist from the Muslim world to have been conferred the UNESCO Science Prize in 1999.[11] He has been conferred honorary doctorate degrees by many universities including the degree of Doctor of Science (Sc.D.) by Cambridge University (UK) (1987) and an Honorary degree of Doctor of Education by Coventry University UK in November 2007. He was elected Honorary Life Fellow of Kings College, Cambridge University, UK in 2007. Prof. Atta-ur-Rahman was conferred the TWAS Prize for Institution Building in Durban, South Africa in October 2009 in recognition of his contributions for bringing about revolutionary changes in the higher education sector in Pakistan. He was awarded the Engro Excellence Award in Science & Technology 2011 for meritorious contributions. He is President of Network of Academies of Sciences of Islamic Countries (NASIC) and the Vice-President (Central & South Asia) of the Academy of Sciences for the Developing World (TWAS) Council, and Foreign Fellow of Korean Academy of Sciences. Prof. Atta-ur-Rahman was the President of the Pakistan Academy of Sciences (2003–06), and was again elected President of Pakistan Academy of Sciences in January 2011. He was the Federal Minister for Science and Technology (14 March 2000 – 20 November 2002), Federal M

Reviews

@qu:A valuable practical guide to the structural elucidation of organic compounds. @source:Journal of Organometallic Chemistry @qu:Atta-ur-Rahman succeeds in conveying the scope and power of one- and two-dimensional NMR and shows clearly how structural information can be extracted. @source:Nature