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Omega Fatty Acids in Brain and Neurological Health - 2nd Edition - ISBN: 9780128152386, 9780128152393

Omega Fatty Acids in Brain and Neurological Health

2nd Edition

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Editors: Ronald Watson Victor Preedy
Hardcover ISBN: 9780128152386
eBook ISBN: 9780128152393
Imprint: Academic Press
Published Date: 13th June 2019
Page Count: 518
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Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases.

Key Features

  • Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research
  • Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6
  • Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment
  • Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases
    • Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements


    Researchers working in neuroscience/neurology research, nutrition research

    Table of Contents

    A. Omega Fatty acids and Brain: An overview
    1. Essentiality of Omega‐3 Polyunsaturated Fatty Acids for Mammalian Brain Development: A Translational Perspective
    2. Thinking in polyunsaturated fatty acids, phospholipids and the brain
    3. The Impact of Omega-3 Fatty Acids on Quality of Life
    4. The Balance Between n-6 and n-3 and its Relation to Executive Function
    5. Arachidonic Acid, Docosahexaenoic Acid, and Ethanol

    B. Omega fatty acids: Brain and neurological development
    6. Prenatal n-3 long-chain polyunsaturated fatty acids and children’s executive functions
    7. Omega-3 and Omega-6 fatty acid metabolism: Modeling growth and disease using Caenorhabditis elegans
    8. Fatty acids and the hippocampus
    9. Energy metabolism of neural cells under the control of phospholipases A2 and docosahexaenoic acid
    10. Omega-3 and Cognition in Children with Malnutrition
    11. Neuroprotective effects of melatonin and omega-3 on the central nervous system exposed to electromagnetic fields in the pre- and postnatal periods
    12. Maternal omega 3 status: effects of cross-fostering on offspring brain lipids and hippocampal neurogenesis
    13. Linking omega-3 fatty acids and depression
    14. Omega 3 Fatty Acids and the Cardiovascular System

    C. Diet and Brain disease treatment and Prevention
    15. Dietary Strategies and Supplements for the Prevention of Cognitive Decline and Alzheimer’s disease
    16. N-3 long chain PUFA-containing phospholipids and neuroprotection
    17. Omega-3 Polyunsaturated Fatty Acid Supplementation as a Potential Protective Factor or Treatment for Neurodegenerative Diseases
    18. Neurobiological meaning of Omega-3 Fatty Acids and their potential role in the treatment of schizophrenia
    19. Neurodevelopmental and behavioral effects of variations in Omega-3 Polyunsaturated Fatty Acids levels in vulnerable populations

    D. Nutrients and the Brain
    20. Omega-3 fatty acids and cognitive behavior
    21. Link between sugar intake and fatty acid metabolism in brain
    22. N-3 and -6 fatty acids in fish: a focus on non-marine species
    23. Aspartame Induced Neurodegeneration Versus Omega 3 Alleviation
    24. DHA-enriched formulations as a promising strategy for the treatment of hypoxic/ischemic brain injury
    25. Alpha-linolenic acid and dementia in epidemiological studies
    26. DHA a Key Supplement For Neurologic Health- An Insight
    27. Obesity, Cognitive Functioning, and Dementia: A Lifespan Perspective
    28. Fatty acids and brain health
    29. Epigenetic effects of omega-3 fatty acids on neurons and astrocytes during brain development and senescence


    No. of pages:
    © Academic Press 2019
    13th June 2019
    Academic Press
    Hardcover ISBN:
    eBook ISBN:

    About the Editors

    Ronald Watson

    Ronald Watson

    Ronald Ross Watson, PhD, is Professor of Health Promotion Sciences at the University of Arizona, Mel and Enid Zuckerman College of Public Health. Dr. Watson began his research in public health at the Harvard School of Public Health as a Fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia and the United States which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring as a Lt. Colonel. He is a distinguished member of several national and international nutrition, immunology, and cancer societies. Dr. Watson’s career has involved studying many lifestyle aspects for their uses in health promotion. He has edited over 100 biomedical reference books and 450 papers and chapters. His teaching and research focuses on alcohol, tobacco, and drugs of abuse in heart function and disease in mouse models.

    Affiliations and Expertise

    Professor, Mel and Enid Zuckerman College of Public Health and School of Medicine, Arizona Health Sciences Center, University of Arizona, Tucson, AZ, USA

    Victor Preedy

    Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

    Affiliations and Expertise

    Professor of Nutritional Biochemistry, Department of Nutrition and Dietetics, Professor of Clinical Biochemistry, Department of Clinical Biochemistry; Director of the Genomics Centre, King’s College, London, UK

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