Clinical Presentation, Pathology, Molecular Biology, Imaging, and Treatment

1st Edition - June 18, 2019

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  • Editors: Nina Paleologos, Herbert Newton
  • Hardcover ISBN: 9780128131589
  • eBook ISBN: 9780128131596

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Oligodendroglioma: Clinical Presentation, Pathology, Molecular Biology, Imaging, and Treatment features the latest "cutting-edge" molecular biology, molecular therapeutics, imaging, immunotherapy, and research methods on the topic of oligodendrogliomas. The most detailed and comprehensive resource on the subject, it provides up-to-date information on clinical presentation, pathology, molecular biology, and treatment methods, including immunotherapy. This book is a critical for students, physicians and researchers in the fields of neuroscience, neuro-oncology, neurosurgery, radiation oncology, medical oncology, and others working in research or with patients.

Key Features

  • Provides the most up-to-date information regarding the clinical presentation, pathology, molecular biology, and methods for the treatment of oligodendroglioma brain tumors, including surgical therapy, radiotherapy, molecular therapeutics, chemotherapy, and immunotherapy
  • Broadly appeals to anyone interested in the field of neuro-oncology and the treatment of patients with oligodendrogliomas
  • Useful to clinicians interested in a thorough overview of the basic science and treatment of oligodendrogliomas
  • Includes a section on immunotherapy, with updates on the use of vaccines and immune-based treatment approaches applied to oligodendrogliomas


Neuroscientists, neurobiologists, neuro-oncologists, neurologists, post-doctoral fellows, researchers, graduate students in biological and biomedical sciences

Table of Contents

    1. Clinical Presentation in Adults - Brain
    2. Clinical Presentation of Spinal Oligodendrogliomas
    3. Oligodendrogliomas – Atypical Clinical Presentations
    4. Clinical Presentation of Pediatric Oligodendrogliomas
    5. Seizures & Oligo’s
    6. Living with Oligodendroglioma

    7. Origin and Development of Oligodendroglioma
    8. Pathology and Molecular Biology Oligo’s
    9. The role of biomarkers in the diagnosis and treatment of oligodendrogliomas
    10. Prospects of translational proteomics and protein microarrays in oligodendroglioma
    11. Pathology of Pediatric Oligodendroglioma

    12. CT Imaging of Oligodendroglioma
    13. Routine and Advanced Magnetic Resonance Imaging of Oligodendrogliomas
    14. Advanced [11C]Methionine and [18F]FDG Positron Emission Tomography for Diagnosis, Treatment, and Follow Up of Oligodendrogliomas
    15. Neuroimaging of Pediatric Oligodendrogliomas

    16. Oligodendrogliomas: Basic Techniques in Surgery
    17. Oligodendrogliomas: Advanced Techniques in Surgery
    18. Surgical management of 1p/19q co-deleted oligodendrogliomas WHO grade II and III
    19. Surgical Results in Anaplastic Oligodendroglioma (AO) and Anaplastic Oligoastrocytoma (AOA)
    20. Surgical Management of Pediatric Oligodendroglioma

    21. Basic Principles of Brain Tumor Radiotherapy
    22. Standard External Beam Radiation Therapy for Oligodendroglioma
    23. Stereotactic Radiosurgery in the management of Oligodendroglioma
    24. Proton Beam Therapy for Oligodendroglioma
    25. Interstitial Brachytherapy treatment for Oligodendrogliomas
    26. The Role of Radiation in Pediatric Oligodendrogliomas

    27. Basic Principles of Brain Tumor Chemotherapy
    28. The use of PCV Chemotherapy in Oligodendrogliomas
    29. Temozolomide Chemotherapy for Oligodendroglial Tumors
    30. Miscellaneous Chemotherapy Approaches to Oligodendroglial Tumors
    31. Molecular Therapy for Oligodendrogliomas
    32. Bevacizumab for Recurrent Anaplastic Oligodendroglial Tumors
    33. Pediatric Oligodendroglioma
    34. Immune Checkpoint Blockade in Glioma

Product details

  • No. of pages: 422
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: June 18, 2019
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128131589
  • eBook ISBN: 9780128131596

About the Editors

Nina Paleologos

Dr. Paleologos is currently Director of Neuro Oncology and Director of Neurology for Advocate Medical Group, the largest physician group in Illinois, with Advocate Healthcare including 12 Hospitals in Illinois. Advocate Healthcare is also part of Advocate Aurora Health. She is also Professor (Adjunct) of Neurological Sciences, Rush University Medical School in Chicago, IL. She has published over 60 journal articles and book chapters in the fields of Neuro-Oncology and Neurology. She has been named as a Best Doctor’s in America (2005-2019) and as a Top Doctor in Chicago in Neurology for several years. She was one of two neuro oncologists named as Chicago Magazine's best neuro oncologists in Chicago and received a Career Acheivement Award from the Chicago Neurological Society for "exceptional expertise, knowledge, dedication and recognition in the field of Neuro-Oncology" in 2013. She has been Chair of the Section of Neurology for the American Academy of Neurology, and is Chairman of the Neuro Oncology Exam Committee for the United Council of Neurological Subspecialities.

Affiliations and Expertise

Director of Neuro-Oncology and Medical Director of Neurology, Advocate Medical Group, Advocate Healthcare; Professor (Adjunct) of Neurological Sciences, Rush University Medical School, Chicago, IL, USA

Herbert Newton

Herbert Newton
Dr. Newton is currently the Director of the Neuro-Oncology Center and CNS Oncology Program at the Advent Health Cancer Institute and Advent Health Orlando Campus. He recently retired as Professor of Neurology and Neurosurgery at the Ohio State University Medical Center and the James Cancer Hospital, and was the holder of the Esther Dardinger Endowed Chair in Neuro-Oncology. He trained in Neuro-Oncology with Drs. Jerome Posner and William Shapiro at Memorial Sloan-Kettering Cancer Center in New York, and since then had been in academic Neuro-Oncology for over 25 years. He has published more than 220 peer-reviewed articles and book chapters, and is the Chief Editor or Co-Editor of ten textbooks in the field of Neurology and Neuro-Oncology. In addition, he has been listed as a Best Doctor (Neurology) and Top Doctor for Cancer (Neuro-Oncology) for the past 18 years.

Affiliations and Expertise

Director, Neuro-Oncology Center, Medical Director, CNS Oncology Program, Advent Health Cancer Institute, Advent Health Orlando, Campus & Advent Health Medical Group, Professor of Neurology, UCF School of Medicine, Orlando, FL, USA

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  • Prof S. Wed Jun 19 2019


    Excellent initiative and wonderful chapters. I would highly recommend to clinicians and researchers working in this area to read this book.