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1. Fluorescence microscopy methods for the study of protein oligomerization
Roberto Arturo Petazzi, Amit Koikkarah Aji and Salvatore Chiantia
2. Computational prediction and redesign of aberrant protein oligomerization
Jaime Santos, Valentín Iglesias and Salvador Ventura
3. Porphobilinogen synthase: An equilibrium of different assemblies in human health
Eileen K. Jaffe
4. Prediction and targeting of GPCR oligomer interfaces
Carlos A.V. Barreto, Salete J. Baptista, António José Preto, Pedro Matos-Filipe, Joana Mourão, Rita Melo and Irina Moreira
5. Integrated structural modeling and super-resolution imaging resolve GPCR oligomers
Francesca Fanelli, Aylin C. Hanyaloglu and Kim Jonas
6. Exploring functional consequences of GPCR oligomerization requires a different lens
Kyla Bourque, Jace Jones-Tabah, Dominic Devost, Paul B.S. Clarke and Terence E. Hébert
7. Continuing challenges in targeting oligomeric GPCR-based drugs
Joaquin Botta, Julia Appelhans and Peter J. McCormick
8. Adenosine A2A-dopamine D2 receptor-receptor interaction in neurons and astrocytes: Evidence and perspectives
Diego Guidolin, Manuela Marcoli, Cinzia Tortorella, Guido Maura and L. Francesco Agnati
9. Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action
Faron-Górecka Agata, Kuśmider Maciej, Solich Joanna, Górecki Andrzej and Dziedzicka-Wasylewska Marta
10. Oligomerization of G protein-coupled receptors: Still doubted?
Sergi Ferré, Francisco Ciruela, Vicent Casadó and Leonardo Pardo
Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scientiﬁc importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine β-synthase, and Oligomerization of Porphobilinogen Synthase.
- Includes comprehensive coverage of molecular biology
- Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided
- Contains contributions from renowned experts in the field of molecular biology
Scientists working actively in a field, including those at levels ranging from graduate student to senior investigator. New investigators to a field who wish to familiarize themselves with the latest work
- No. of pages:
- © Academic Press 2020
- 15th January 2020
- Academic Press
- Hardcover ISBN:
- eBook ISBN:
Dr.Jesús Giraldo currently teaches at Universitat Autònoma de Barcelona in Barcelona, Spain.
Universitat Autonoma de Barcelona, Spain
Dr. Francisco Ciruela currently teaches at University of Barcelona, Barcelona, Spain.
University of Barcelona, Spain
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