Nutritional Epigenomics - 1st Edition - ISBN: 9780128168431

Nutritional Epigenomics, Volume 15

1st Edition

Series Volume Editors: Bradley Ferguson
Paperback ISBN: 9780128168431
Imprint: Academic Press
Published Date: 1st August 2019
Page Count: 488
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Table of Contents

1. Introduction to nutritional epigenomics
2. DNA methylation and chromatin modifications
3. Non-coding RNAs as epigenetic regulators
4. The impact of race and ethnicity in the social-epigenomic regulation of disease
5. The epigenomic impact of methylation in metabolic dysfunction and cancer
6. The role for methylation on neurocognitive dysfunction
7. Histone acetylation in the epigenomic regulation of metabolic disease
8. Cancer and non-coding RNAs
9. Race and ethnicity in the social-epigenomic regulation of perinatal development
10. Maternal diet and epigenomic programming during in utero life
11. Maternal regulation of non-coding RNAs contributes to transgenerational inheritance of metabolic dysfunction
12. The paternal diet regulates the offspring epigenome and health
13. The interplay between diet, epigenetics and the circadian clock
14. Epigenetic regulation of the fetal circadian clock: implications for nutritional programming of circadian and metabolic function
15. The role for the microbiome in the regulation of the circadian clock and metabolism
16. Epigenomic reprogramming from caloric restriction on aging
17. Dietary restriction in the epigenomic regulation of cardiovascular disease
18. Epigenomic adaptations of exercise in the control of metabolic disease and cancer
19. Folate and the B vitamins impact the epigenome during development
20. Food bioactives in the epigenomic regulation of metabolic disease
21. Dietary regulators of the cancer epigenome
22. Plant phytochemicals regulate small non-coding RNAs in disease
23. Fatty acids as epigenomic regulators of neurocognitive health and disease
24. Diet-microbiome interactions and the regulation of the epigenome
25. Gut dysbiosis and its epigenomic impact on disease
26. The gut microbiome, epigenetics and the brain


Nutritional Epigenomics offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders.

Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease.

Key Features

  • Empowers the reader to employ nutritional epigenomics approaches in their own research
  • Discusses the latest topics in nutritional epigenomics in the regulation of aging, circadian rhythm, inheritance and fetal development, as well as metabolism and disease
  • Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies


Academic and industry researchers in the fields of nutrition, kinesiology, public health, psychology, medicine, pharmacy, human genetics, genomics, biology, molecular biology, biochemistry, and cardiology; advanced undergraduate students, graduate students, postgraduates


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© Academic Press 2019
Academic Press
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Ratings and Reviews

About the Series Volume Editors

Bradley Ferguson Series Volume Editor

Dr. Bradley Ferguson is Assistant Professor of Nutrition at the University of Nevada, Reno, NV. His lab adopts integrative, translational research approaches that encompass bioinformatics, in vitro cell culture, and in vivo animal models to elucidate dietary food components that act as epigenetic modifiers, as well as the role of dietary epigenetic modifiers on pathological cardiac signaling, gene expression, and remodeling. He also seeks to understand how acetylation and deacetylation links metabolic disease (obesity and diabetes) to pathological cardiac remodeling and dysfunction. Dr. Ferguson has published his findings across a wide range of peer reviewed journals, including Scientific Reports, Journal of Animal Science, Current Pharmaceutical Design, and the Journal of Molecular and Cellular Cardiology.

Affiliations and Expertise

Assistant Professor of Nutrition, University of Nevada, Reno, NV, USA