Nutrition and Immunity

Nutrition and Immunity

1st Edition - May 10, 1985

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  • Author: M Gershwin
  • eBook ISBN: 9780323150736

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Nutrition and Immunity discusses the interaction between nutrition, immune function, and immunity, based on empirical and epidemiologic point of view. It is organized into 14 chapters that focus on experimental studies on laboratory animals, including animal models to isolate specific factors in the interaction between nutrition and immunity. The book starts with an introduction to the potential impact of nutritional factors on immune responsiveness. Two chapters deal with the evaluation of immune function and nutritional assessment. Other chapters present classic observations on malnutrition and infectious disease, involving field studies as well as studies on the effect of nutritional factors on immune ontogeny. The following chapters examine issues related to caloric intake, proteins, minerals, vitamins, lipids, breast milk, and alcohol, as well as their effects in immune function and immunity. The book’s final chapters cover future directions and the potential role of nutritional modulation in immune dysfunction. Each chapter is meant to be an authoritative review presenting the state of the art as well as providing key illustrations from classic papers in a given field. Nutritionists, immunologists, scientists, and researchers will find this book very helpful in expanding their knowledge in the interrelationship between nutrition and immunity.

Table of Contents

  • Preface

    1. The Potential Impact of Nutritional Factors on Immunologic Responsiveness


    The Influence of Nutritional Factors on Immunological Parameters

    Nutritional Sequelae of Infectious Disease

    Means of Investigating the Interactions between Nutrition, Immunity, and Infectious Disease

    The Spectrum of Interactions between Nutrition and Immunology

    2. Evaluation of Immunologic Function


    Experimental Work in Animals

    Experiments of Nature

    Identification and Properties of T Cells

    Characteristics of B Cells

    Characteristics of Null Cells

    Regulation of the Immune Response

    In Vivo Methods for Evaluation of Cell-Mediated Immunity

    In Vitro Methods for Evaluation of Cell-Mediated Immunity

    In Vitro Evaluation of B Cells

    Evaluation of Immunoglobulin Status

    Evaluation of Phagocytosis


    3. Nutritional Assessment


    Application of Techniques

    4. Malnutrition and Infectious Disease: Studies from the Field


    Nutritional Surveys

    Brief Characterization of PEM

    Protein Energy Malnutrition and Infectious Disease: Synergistic Interactions

    Immunological Defenses in PEM

    Humoral Immunity in PEM

    Nonspecific Immune Function in PEM

    5. Nutritional Factors and Immune Ontogeny


    Human Studies

    Experimental Animal Studies

    6. Caloric Intake


    Caloric Deficit and Immunological Function

    Disorders of Caloric Excess

    7. Protein


    Protein and Response to Infectious Disease

    Dietary Protein and the Humoral Immune Response

    Effect of Lymphoid Tissue

    Protein and Cell-Mediated Immune Function

    Protein Nutriture and Other Immune Mechanisms

    Amino Acids

    8. Trace Elements


    Trace Elements and Immunity




    Other Minerals

    Mineral Interactions

    9. Vitamins


    Vitamin A

    Vitamin D

    Vitamin E

    B Complex Vitamins

    Folate and B12

    Vitamin C

    Pantothenic Acid


    10. Lipids


    Diet and Cell Membranes

    In Vitro Studies

    In Vivo Effects of Fatty Acids

    Lipids and Experimental Allergic Encephalomyelitis


    Studies in Humans

    11. Immunological Considerations of Breast Milk


    Influence of Nutrition on Lactation

    Nutritional Requirements during Lactation

    Nutrition of the Infant

    Modification of Cow's Milk for Infant Feeding: Formulas

    The Relationship between Milk and Neonatal Infections

    12. Alcohol and Immune Function


    Alcohol and Infectious Disease

    Studies in Animals

    Ethanol and Humoral Immunity

    Ethanol and Cell-Mediated Immunity

    13. Nutritional Modulation of Autoimmune Disease


    Experimental Models of Autoimmunity

    Amino Acids, Protein, and Autoimmune Disease

    Calories and Autoimmune Disease

    Lipids and Autoimmune Disease

    Vitamins and Autoimmune Disease

    Minerals and Autoimmune Disease

    Mechanistic Considerations

    Applications in Clinical Medicine

    14. Future Directions




Product details

  • No. of pages: 430
  • Language: English
  • Copyright: © Academic Press 1985
  • Published: May 10, 1985
  • Imprint: Academic Press
  • eBook ISBN: 9780323150736

About the Author

M Gershwin

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