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Novel Designs of Early Phase Trials for Cancer Therapeutics

  • 1st Edition - May 22, 2018
  • Editors: Shivaani Kummar, Chris Takimoto
  • Language: English
  • Paperback ISBN:
    9 7 8 - 0 - 1 2 - 8 1 2 5 1 2 - 0
  • eBook ISBN:
    9 7 8 - 0 - 1 2 - 8 1 2 5 7 0 - 0

Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular… Read more

Novel Designs of Early Phase Trials for Cancer Therapeutics

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Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials.

This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials.