COVID-19 Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. To provide all customers with timely access to content, we are offering 50% off Science and Technology Print & eBook bundle options. Terms & conditions.
Nonviral Vectors for Gene Therapy, Part 1 - 2nd Edition - ISBN: 9780120176533

Nonviral Vectors for Gene Therapy, Part 1, Volume 53

2nd Edition

Editors: Leaf Huang Mien-Chie Hung Ernst Wagner
Hardcover ISBN: 9780120176533
Imprint: Academic Press
Published Date: 7th July 2005
Page Count: 392


This product is currently not available for sale.

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Table of Contents

Recent Advances in Non-viral Gene Delivery; Barriers to gene delivery using synthetic vectors; Pharmacokinetics of Plasmid DNA-Based Nonviral Gene Medicine; What Role can chemistry play in cationic liposome-based gene therapy research today?; Lipoplex structures and their distinct cellular pathways; Toxicity of Catonic lipid-DNA complexes; Polyethylenimine (PEI); Pluronic Block Copolymers for gene delivery; Terplex gene delivery system; Design of polyphosphoester-DNA nanoparticles for nonviral gene delivery; Development of HVJ envelope vector and its application to gene therapy; Targeting of polyplexes: towards synthetic virus vector systems.


The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therapeutics are fully covered in these volumes.


Graduate students, scientists, and clinicians interested in molecular and cell biology interested in gene therapy.


No. of pages:
© Academic Press 2005
7th July 2005
Academic Press
Hardcover ISBN:

Ratings and Reviews

About the Editors

Leaf Huang

Affiliations and Expertise

Department of Biomedical Engineering, University of North Carolina at Chapel Hill, North Carolina, U.S.A.

Mien-Chie Hung

Affiliations and Expertise

M.D. Anderson Cancer Center, University of Texas, Houston, U.S.A.

Ernst Wagner

Affiliations and Expertise

Munich Center for System-based Drug Research, Center for Nanoscience, Ludwig-Maximilians-Universität, Germany