Nitric Oxide

Nitric Oxide

1st Edition - June 27, 2007

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  • Editors: Bruno Tota, Barry Trimmer
  • eBook ISBN: 9780080546209
  • Hardcover ISBN: 9780444531193

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This volume provides a novel insight to the evolutionary and comparative aspects of nitric oxide- nitric oxide synthase system as a central regulator of invertebrate and vertebrate homeostasis. By critically selecting and summarizing the ever–increasing number of original studies, these presentations review a variety of important signalling and modulatory roles played by nitric oxide at molecular, cell, organ and organ system levels. It addresses not only specialists and graduate students in the field, but also all biologists concerned with how this unique, gaseous, pleiotropic molecule has been employed by living systems, uncovering a new dimension of the wonders of life.


Experimental biologists, researchers in developmental cell and comparative biology within animal and plant biology.

Table of Contents

  • 1. On the Comparative Biology of NO Synthetic Pathways: Parallel Evolution of NO-Mediated Signaling

    Leonid L. Moroz and Andrea B. Kohn

    2. Nitric Oxide Biogenesis, Signalling and Roles in Molluscs: The Sepia officinalis Paradigm

    Anna Palumbo and Marco d’Ischia

    3. Soluble Guanylyl Cyclases in Invertebrates: Targets for NO and O2

    David B. Morton and Anke Vermehren

    4. Nitric Oxide Signalling in Insect Epithelial Transport

    Shireen-A. Davies

    5. Nitric Oxide/Cyclic GMP Signaling and Insect Behavior

    Ralf Heinrich and Geoffrey K. Ganter

    6. Impact of Nitrative/Nitrosative Stress in Mitochondria: Unraveling Targets for Malaria Chemotherapy

    Shirley Luckhart, Kazunobu Kato and Cecilia Giulivi

    7. Effects of S-Nitrosation of Nitric Oxide Synthase

    Douglas A. Mitchell, Thomas Michel and Michael A. Marletta

    8. Regulatory Role and Evolution of Unconventional NOS-Related RNAs

    Sergei Korneev and Michael O’Shea

    9. The Role of Blood Nitrite in the Control of Hypoxic Vasodilation

    Angela Fago and Frank B. Jensen

    10. Nitrite is a Vascular Store of NO which Mediates Hypoxic Signaling and Protects against Ischemia/Reperfusion Injury

    Cameron Dezfulian, Mark T. Gladwin and Sruti Shiva

    11. Nitric Oxide and the Zebrafish (Danio rerio): Developmental Neurobiology and Brain Neurogenesis

    Bo Holmqvist, Lars Ebbesson and Per Alm

    12. NO in the Development of Fish

    Bernd Pelster

    13. Role of Nitric Oxide in Vascular Regulation in Fish

    Claudio Agnisola and Daniela Pellegrino

    14. NOS Distribution and NO Control of Cardiac Performance in Fish and Amphibian Hearts

    Bruno Tota, Sandra Imbrogno, Rosa Mazza and Alfonsina Gattuso

    15. Nitric Oxide and Histamine in Hibernation and Neuroprotection

    Pertti Panula, Giuseppina Giusi, Rosa Maria Facciolo, Tina Sallmen, Minamaija Lintunen and Marcello Canonaco

    16. Nitric Oxide, Peroxynitrite and Matrix Metalloproteinases: Insight into the Pathogenesis of Sepsis

    Jonathan Cena, Ava K. Chow and Richard Schulz

Product details

  • No. of pages: 468
  • Language: English
  • Copyright: © Elsevier Science 2007
  • Published: June 27, 2007
  • Imprint: Elsevier Science
  • eBook ISBN: 9780080546209
  • Hardcover ISBN: 9780444531193

About the Series Volume Editors

Bruno Tota

Affiliations and Expertise

Universita della Calabria, Arcavacata de Rende, Italy

Barry Trimmer

Affiliations and Expertise

Tufts University School of Medicine, Boston, MA, USA

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