Description

Nitric oxide, recently named"Molecule of the Year"by the journal Science, impinges on a wide range of fields in biological research, particularly in the areas of biomedicine and cell and organismal biology, as well as in fundamental chemistry. This volume and its companion Volume 269 highlight the most current and up-to-date methods used to research the physiology and toxicity of nitric oxide in cellular and organismal systems. It will be a valuable resourcefor the experienced researcher as well as for those newly entering the field.

Key Features

@introbul:Key Features @bul:* Generation, detection, and characterization of biological and chemical sources of nitric oxide * Biochemistry and molecular biology of enzymes and proteins associated with nitric oxide metabolism

Readership

Biochemists, molecular biologists, physiologists, pharmacologists, cell biologists, biomedical researchers, and neuroscientists.

Table of Contents

Generation, Detection, and Characterization of Biological and Chemical Sources of Nitric Oxide: Nitric Oxide Chemistry and Biology: W.H. Koppenol and J.G. Traynham, Say NO for Nitric Oxide: Nomenclature forNitrogen- and Oxygen-Containing Compounds. W.H. Koppenol, Thermodynamics of Reactions Involving Nitrogen–Oxygen Compounds. D.A. Wink, M.B. Grisham, J.B. Mitchell, and P.C. Ford, Direct and Indirect Effects of Nitric Oxide in Chemical Reactions Relevant to Biology. J.R. Lancaster, Jr., Diffusion of Free Nitric Oxide. F.T. Bonner, Nitric Oxide Gas. Methods for Detection of Nitric Oxide: T. Malinski, S. Mesaros, and P. Tomboulian, Nitric Oxide Measurement Using Electrochemical Methods. D. Christodoulou, S. Kudo, J.A. Cook, M.C. Krishna, A. Miles, M.B. Grisham, R. Murugesan, P.C. Ford, and D.A. Wink, Electrochemical Methods for Detection of Nitric Oxide. J.F. Brien, B.E. McLaughlin, K. Nakatsu, and G.S. Marks, Chemiluminescence Headspace–Gas Analysis for Determination of Nitric Oxide Formation in Biological Systems. R.W. Nims, J.C. Cook, M.C. Krishna, D. Christodoulou, C.M.B. Poore, A.M. Miles, M.B. Grisham, and D.A. Wink, Colorimetric Assaysfor Nitric Oxide and Nitrogen Oxide Species Formed from Nitric Oxide Stock Solutions and Donor Compounds. A.M. Miles, D.A. Wink, J.C. Cook, and M.B. Grisham, Determination of Nitric Oxide Using Fluorescence Spectroscopy. D.A. Wink, M.B. Grisham,A.M. Miles, R.W. Nims, M.C. Krishna, R. Pacelli, D. Teague, C.M.B. Poore, J.A. Cook, and P.C. Ford, Determination of Selectivity of Reactive Nitrogen Oxide Species for Various Substrates. J.S. Wishnok, J.A. Glogowski, and S.R. Tannenbaum, Quantitation of Nitrate, Nitrite, and Nitrosating Agents. D.L. Granger, R.R. Taintor, K.S. Boockvar, and J.B. Hibbs, Jr., Measurement of Nitrate and Nitrite in Biological Samples Using Nitrate Reductase and

Details

No. of pages:
555
Language:
English
Copyright:
© 1996
Published:
Imprint:
Academic Press
eBook ISBN:
9780080883816
Print ISBN:
9780121821692

About the serial-volume-editor

Helmut Sies

Helmut Sies is an Honorary Member of the American Society for Biochemistry and Molecular Biology. He received an Honorary Ph.D. from the University of Buenos Aires, Argentina in 1996. Dr. Sies is a member of the Northrhine-Westphalian Academy of Sciences, Germany, and a Corresponding Member of both the Academy of Sciences of Heidelberg, Germany, and the Academy of Medicine, Buenos Aires, Argentina. He has received many awards and prizes, including the FEBS Anniversary Prize awarded by the Federation of European Biochemical Societies, 1978; the Distinguished Foreign Scholar award, MASUA, 1985; the Silver Medal, Karolinska Institute, Stockholm, 1986; the Ernst Jung Preis fur Medizin, 1988; the Claudius-Galenus-Preis, 1990; and the ISFE-Preis, 1994. Dr. Sies sereves on the editorial board and advisory committee for twelve journals, has edited numerous books, and has published more than 400 original articles and chapters. He received his M.D. at the University of Munich in 1967 and currently serves as Full Professor and Chairman of the Department of Physiological Chemistry at the University of Düsseldorf.

Affiliations and Expertise

Institut Fur Physiologische Chemie, Germany

Reviews

@from:Praise for the Series @qu:"The Methods in Enzymology series represents the gold-standard." @source:--NEUROSCIENCE @qu:"Incomparably useful." @source:--ANALYTICAL BIOCHEMISTRY @qu:"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page." @source:--BIO/TECHNOLOGY @qu:"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection." @source:--CHEMISTRY IN INDUSTRY @qu:"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced." @source:--AMERICAN SOCIETY OF MICROBIOLOGY NEWS @qu:"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work." @source:--ENZYMOLOGIA @qu:"A series that has established itself as a definitive reference for biochemists." @source:--JOURNAL OF CHROMATOGRAPHY