Next-Generation Interstitial Lung Disease, An Issue of Clinics in Chest Medicine

1st Edition, Volume 42-2 - June 3, 2021
Editors: Harold R Collard, Luca Richeldi, Kerri A. Johannson
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 5 7 8 3 - 6
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 5 7 8 4 - 3

In this issue of Clinics in Chest Medicine, Guest Editors Harold R Collard, Luca Richeldi, and Kerri A. Johannson bring their considerable expertise to the topic of Next-gene… Read more

Next-Generation Interstitial Lung Disease, An Issue of Clinics in Chest Medicine

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In this issue of Clinics in Chest Medicine, Guest Editors Harold R Collard, Luca Richeldi, and Kerri A. Johannson bring their considerable expertise to the topic of Next-generation Interstitial Lung Disease.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Interstitial Lung Disease in 2020: A History of Progress
Key points
Introduction
Evolution of interstitial lung disease classification and terminology
Pathogenesis
Epidemiology
Diagnosis
Management
Summary
Clinics care points
Clinical Relevance and Management of “Pre–Interstitial Lung Disease”
Key points
Introduction
Definitions
Epidemiology
Risk factors
Pathology
Clinical implications
Clinical management
Areas of uncertainty and future directions
Summary
Clinics care points
Diagnostic Classification of Interstitial Lung Disease in Clinical Practice
Key points
Background
Evolution of interstitial lung disease classification
Diagnostic tools routinely employed to support interstitial lung disease classification
Contemporary approaches to interstitial lung disease classification
Future perspectives
Summary
Clinics care points
Author's contributions
Rethinking Idiopathic Pulmonary Fibrosis
Key points
Introduction
Rethinking idiopathic pulmonary fibrosis pathogenesis
Rethinking idiopathic pulmonary fibrosis diagnosis
Rethinking idiopathic pulmonary fibrosis treatment
Challenges ahead
Clinics care points
Management of Idiopathic Pulmonary Fibrosis
Key points
Introduction
Patient and caregiver education: applications to disease management
Disease-modifying therapy for idiopathic pulmonary fibrosis
Supportive measures and managing comorbidities
Summary
Clinics care points
Disclosure
Clinical Trials for Idiopathic Pulmonary Fibrosis and the Role of Health Systems
Key points
Introduction
Nature of the problem
The role of health systems in clinical research
The future of clinical trials in idiopathic pulmonary fibrosis
Summary
Disclosure
Management of Connective Tissue Disease-Associated Interstitial Lung Disease
Key points
Introduction
Initial approach
Immunosuppressive treatment stratified by connective tissue disease
Antifibrotics
Ongoing clinical trials
Nonpharmacologic treatment
Treatment of comorbidities
Lung transplant
Summary
Clinics care points
Management of Fibrotic Hypersensitivity Pneumonitis
Key points
Introduction
Establishing an accurate diagnosis
Associated risk factors
Management
Summary
Clinics care points
Diagnosis and Management of Fibrotic Interstitial Lung Diseases
Key points
Introduction
Definition of non–idiopathic pulmonary fibrosis progressive fibrotic lung disease
Subsets of progressive fibrotic interstitial lung disease
Diagnosis
Treatment
Clinical course/prognosis
Future directions
Clinics care points
Providing Patient-Centered Care in Interstitial Lung Disease
Key points
Introduction
Patient-centered approach in clinical care
Patient-centered care in research
Dyspnea
Cough
Health-related quality of life
Sleep and fatigue
Anxiety and depression
Future directions
Summary
Clinics care points
Care Delivery Models and Interstitial Lung Disease: The Role of the Specialized Center
Key points
Introduction
Key components of interstitial lung disease care and the role of the specialized center in delivery
Challenges facing interstitial lung disease care delivery models and proposed solutions
Summary
Clinics care points
Molecular Markers and the Promise of Precision Medicine for Interstitial Lung Disease
Key points
Introduction
Omics pipeline
Genomics
Epigenomics
Transcriptomics
Proteomics
Metabolomics
Challenges and opportunities in omics-based biomarker development
A roadmap to precision medicine in interstitial lung disease
Summary
Clinics care points
Regenerative Medicine and the Hope for a Cure
Key points
Regenerative potential of the (diseased) lung
Idiopathic pulmonary fibrosis as a disease of impaired regeneration
Therapeutic intervention
Conclusion and future outlook
Clinics care points
Looking Ahead: Interstitial Lung Disease Diagnosis and Management in 2030
Key points
Introduction
Summary