New Insights on the Development of the Vascular System

New Insights on the Development of the Vascular System

1st Edition - June 2, 2022

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  • Author: Domenico Ribatti
  • eBook ISBN: 9780323915793
  • Paperback ISBN: 9780323905992

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Description

New Insights on the Development of the Vascular System examines the most recent literature and data on the development of the vascular system, along with advice on new laboratory techniques and approaches to data analysis. This volume is a comprehensive handbook to the state-of-the-art in vascular system development. Several genetic and epigenetic mechanisms are involved in the early development of the vascular system, and there is extensive literature on the genetic background and molecular mechanisms responsible for blood vessel formation. Yet new data and techniques have been developed in recent years. Although scientific literature covers the descriptive aspects of embryonic vascular system development, modern techniques such as the technology of cell fusion, cell sorting and image analysis give new insight into the mechanisms by which vessels form and regress and how blood flow changes directions in the same vessels.

Key Features

  • Gives a comprehensive overview of the most recent literature in the field of vascular system development
  • Presents new data, including sections on endothelial cell signaling and technologies of cell fusion, cell sorting and image analysis
  • Provides useful insights on the analysis of new experimental work
  • Suggests modern techniques for scientists to use in the lab
  • Gives an overview of vascular biology that will be useful for those needing rapid familiarity
  • Provides an expert guide to the state-of-the-art in vascular system development as written by a leader in the field

Readership

Researchers in biochemistry, vascular biology, cell and molecular biology, physiology, neurology, oncology, pathology, cardiology, rheumatology, ophthalmology, and genetics. Advanced students in vascular biology and pharmaceutics

Table of Contents

  • Cover
  • Title page
  • Table of Contents
  • Copyright
  • Preface
  • Chapter 1: Introduction
  • Abstract
  • References
  • Chapter 2: Vasculogenesis
  • Abstract
  • References
  • Chapter 3: Angiogenesis
  • Abstract
  • References
  • Chapter 4: Nonsprouting angiogenesis: Intussusceptive microvascular growth
  • Abstract
  • References
  • Chapter 5: Endothelial tip, stalk, and phalanx cells
  • Abstract
  • References
  • Chapter 6: Role of neuropilins
  • Abstract
  • References
  • Chapter 7: Role of notch and notch ligands
  • Abstract
  • References
  • Chapter 8: Semaphorins and netrin-UNC5B signaling
  • Abstract
  • References
  • Chapter 9: Lumen formation and perfusion
  • Abstract
  • References
  • Chapter 10: Network formation
  • Abstract
  • References
  • Chapter 11: Remodeling
  • Abstract
  • References
  • Chapter 12: Pruning
  • Abstract
  • References
  • Chapter 13: Maturation and stabilization and pericyte recruitment
  • Abstract
  • References
  • Chapter 14: Arteriogenesis
  • Abstract
  • References
  • Chapter 15: Arterial and venous specification
  • Abstract
  • References
  • Chapter 16: Role of oxygen
  • Abstract
  • References
  • Chapter 17: Epigenetic regulation of vascular development (microRNAs)
  • Abstract
  • References
  • Chapter 18: Angiogenesis and organogenesis
  • Abstract
  • Liver
  • Pancreas
  • Kidney
  • Bone
  • Lung
  • Brain
  • References
  • Chapter 19: Concluding remarks
  • Abstract
  • References
  • Index

Product details

  • No. of pages: 124
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: June 2, 2022
  • Imprint: Academic Press
  • eBook ISBN: 9780323915793
  • Paperback ISBN: 9780323905992

About the Author

Domenico Ribatti

Domenico Ribatti was awarded his M.D. degree in October 1981, with full marks. In 1983, D.R. joined the Medical School as Assistant at the Institute of Human Anatomy, University of Bari. In 1984, he took the specialization in Allergology. In 1989, he spent one year in Geneva, working at the Department of Morphology (Prof. R. Montesano). In 2008, he received the honoris causa degree in Medicine and Pharmacy form the University of Timisoara (Romania). D.R. is author of 866 publications as reported in PUBmed and contributed to 50 chapters to books. Overall, his papers have been cited 51153 times. He has published many books with both Elsevier and Springe

Affiliations and Expertise

Full Professor of Human Anatomy, University of Bari Medical School, Bari, Italy

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