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1. Fundamentals of neutron crystallography in structural biology
John R. Helliwell
2. Large crystal growth for neutron protein crystallography
Monika Budayova-Spano, Katarina Koruza and Zoë Fisher
3. Prospects for membrane protein crystals in NMX
Samuel John Hjorth-Jensen, Esko Oksanen, Poul Nissen and Thomas Lykke-Møller Sørensen
4. IMAGINE: The neutron protein crystallography beamline at the high flux isotope reactor
Flora Meilleur, Andrey Kovalevsky and Dean A.A. Myles
5. The macromolecular neutron diffractometer at the spallation neutron source
Leighton Coates and Brendan Sullivan
6. Current status and near future plan of neutron protein crystallography at J-PARC
Ichiro Tanaka, Toshiyuki Chatake, Satoru Fujiwara, Takaaki Hosoya, Katsuhiro Kusaka, Nobuo Niimura, Taro Yamada and Naomine Yano
7. Neutron macromolecular crystallography at the European spallation source
Márton Markó, Gergely Nagy, Giuseppe Aprigliano and Esko Oksanen
8. Dynamic nuclear polarization enhanced neutron crystallography: Amplifying hydrogen in biological crystals
Joshua Pierce, Matthew J. Cuneo, Ann Jennings, Le Li, Flora Meilleur, Jinkui Zang and Dean A.A. Myles
9. Implementation of the riding hydrogen model in CCTBX to support the next generation of X-ray and neutron joint refinement in Phenix
Dorothee Liebschner, Pavel V. Afonine, Alexandre G. Urzhumtsev and Paul D. Adams
10. Interactive model building in neutron macromolecular crystallography
Derek T. Logan
11. What are the current limits on determination of protonation state using neutron macromolecular crystallography?
Dorothee Liebschner, Pavel V. Afonine, Nigel W. Moriarty and Paul D. Adams
12. Proton transfer and drug binding details revealed in neutron diffraction studies of wild-type and drug resistant HIV-1 protease
Andrey Kovalevsky, Oksana Gerlits, Kaira Beltran, Kevin Weiss, David A. Keen, Matthew P. Blakeley, John M. Louis and Irene T. Weber
13. Neutron crystallographic studies of carbonic anhydrase
Jacob E. Combs, Jacob T. Andring and Robert McKenna
14. Protein kinase A in the neutron beam: Insights for catalysis from directly observing protons
Oksana Gerlits, Kevin L. Weiss, Matthew P. Blakeley, Gianluigi Veglia, Susan S. Taylor and
15. Pyridoxal 5’ phosphate dependent reactions: Analyzing the mechanism of aspartate amino transferase
Timothy C. Mueser, Victoria Drago, Andrey Kovalevsky and Steven Dajnowicz
16. The role of hydrogen atoms in redox catalysis by the flavoenzyme cholesterol oxidase
Tatiana Kerber and Alice Vrielink
17. Heme peroxidase - Trapping intermediates by cryo neutron crystallography
Hanna Kwon, Tobias E. Schrader, Andreas Ostermann, Matthew P. Blakeley, Emma L, Raven and Peter C. E. Moody
Neutron Crystallography in Structural Biology, Volume 634, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this updated release include Fundamentals of neutron crystallography in structural biology, Large crystal growth for neutron protein crystallography, Prospects for membrane protein crystals in NMX, IMAGINE: The neutron protein crystallography beamline at the high flux isotope reactor, The macromolecular neutron diffractometer at the spallation neutron source, Current status and near future plan of neutron protein crystallography at J-PARC, Neutron macromolecular crystallography at the European spallation source, and much more.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Methods in Enzymology series
- Includes the latest information on neutron crystallography in structural biology
Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists.
- No. of pages:
- © Academic Press 2020
- 24th February 2020
- Academic Press
- Hardcover ISBN:
- eBook ISBN:
Peter Moody is Professor of Structural Biology at Leicester Institute for Structural & Chemical Biology, Department of Molecular & Cell Biology, University of Leicester, UK
University of Leicester, UK
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