Proceedings of the Sixth International Congress of Pharmacology

1st Edition - January 1, 1976

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  • Editor: Liisa Ahtee
  • eBook ISBN: 9781483157757

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Neurotransmission is the second volume of the proceedings of the Sixth International Congress of Pharmacology, organized by the Finnish Pharmacological Society and held in Helsinki, Finland, on July 20-25, 1975. The papers focus on the developments in neurotransmission and cover topics ranging from novel transmitter substances and extraneuronal uptake of catecholamines to axonal transport mechanisms and nerve growth factor. This volume has 28 chapters divided into five sections. After discussing the possible functional role of certain tryptaminergic pathways, this book turns its attention to the metabolism of endogenous noradrenaline, with emphasis on the role of 3,4-dihydroxyphenylglycol (DOPEG). The chapters that follow focus on amino acids as possible neurotransmitters, including histamine and glutamate. This text discusses as well the mechanisms underlying extraneuronal amine uptake and metabolism in the salivary glands; the effect of oxytetracycline on the responses of various tissue preparations to added noradrenaline and to field stimulation; and how axoplasmic transport is blocked by pharmacological agents. This book will be of interest to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as interdisciplinary areas related to physiology, biochemistry, and endocrinology. Many of the topics will also appeal to internists, psychiatrists, neurologists, and anaesthesiologists.

Table of Contents

  • Contributors


    Invited Lectures

    Tryptaminergic Neurotransmission

    Metabolism of Endogenous Noradrenaline

    Novel Transmitter Substances

    Symposium on Novel Transmitter Substances — Chairman's Introduction

    Hypothalamic Substance P as a Candidate for the Sensory Transmitter of Spinal Dorsal root Fibers

    ATP and Purinergic Transmission

    Carnosine (β-alanyl-L-histidine) in the Olfactory Nerve: A Putative Transmitter Candidate

    Histamine as a Transmitter in Mammalian Brain

    Glutamate and Other Excitatory Amino Acids in the Mammalian CNS

    Uptake of GABA and Glutamate in Glial Cells in the Nervous System

    Extraneuronal Uptake of Catecholamines

    Extraneuronal Uptake and Metabolism in Rat Salivary Glands

    Extraneuronal Uptake and Metabolism of Catecholamines in Isolated Perfused Hearts

    The Binding of Noradrenaline to Connective and Elastic Tissue

    Extraneuronal Uptake and Metabolism of 3H-/-Noradrenaline in Rabbit Aorta

    Extraneuronal Uptake and Metabolism in Dog Vascular Structures

    Axonal Transport Mechanisms

    Mechanism of Axoplasmic Transport and its Block by Pharmacological Agents

    Effect of Drugs on Axonal Transport of Synaptic Vesicles

    Neurotrophic Control of the Fast and Slow Skeletal Muscle

    Immunocytochemical Localization of Tyrosine Hydroxylase and Tryptophan Hydroxylase in Relation to Microtubules in Rat Brain

    Axonal Transport: Role in the Renewal of Synaptic Vesicles in Cholinergic Neurons

    Nerve Growth Factor

    Chairman's Introduction to the Symposium on "Nerve Growth Factor"

    Milestones, Unanswered Questions and Current Studies on Nerve Growth Factor

    Structure-Function Relationships of Nerve Growth Factor and Insulin

    Studies on the Biosynthesis and Structure of Nerve Growth Factor from the Mouse Submaxillary Gland

    Response of the Adrenergic System to Changes in Tissue and Plasma Levels of Nerve Growth Factor (NGF)

    NGF in Maintenance and Regeneration of Adrenergic Axons

    Glia, Nerve Growth Factor and Ganglionic Metabolism

    Specificity and Biological Importance of Retrograde Axonal Transport of Nerve Growth Factor

    Chairman's Concluding Remarks to the Symposium on "Nerve Growth Factor"

    Contents of Volumes 1-6

    Subject Index

Product details

  • No. of pages: 322
  • Language: English
  • Copyright: © Pergamon 1976
  • Published: January 1, 1976
  • Imprint: Pergamon
  • eBook ISBN: 9781483157757

About the Editor

Liisa Ahtee

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