International Review of Neurobiology, Volume 46 presents in-depth reviews on such ground-breaking topics as assembly and intracellular trafficking of GABA A receptors, D-1 dopamine receptors, and Alzheimer's disease. This series offers the most comprehensive and up-to-date information available and is a must for anyone in the field.

Key Features

Includes a historical overview of neurosteroid research Contains a chapter on neurosteroid biosynthesis and regulation Presents current methods of neurosteroid measurement and analysis Discusses neurosteroid function in both the normal and the pathological brain Chapters address the function of neurosteroid in: Stress Receptor plasticity and function Learning and Memory Alcohol use Depression


Researchers and graduate students in neuroscience, cell genetics, pharmacology, biology, and physiology.

Table of Contents

Neurosteroids: (Beginning of) The Story. Biosynthesis of Neurosteroids and Regulation of their Synthesis. Neurosteroid 7-hydroxylation Products in Brain. Analysis of neurosteroids. Role of Peripheral-Type Benzodiazepine Receptors in Adrenal and Brain Steroidogenesis. Formation and Effects of Neuroactive Steroids in the Central and Peripheral Nervous System. Neurosteroids and GABAA receptor function. GABAA Receptor Plasticity During Long-Term Exposure to and Withdrawal From Progesterone. Stress and Neuroactive Steroids. Neurosteroids in learning and memory processes. Neurosteroids and behaviour. Ethanol and Neurosteroid Interactions in Brain. Preclinical Development of Neurosteroids as Neuroprotective Agents for the Treatment of Neurodegenerative Diseases. Clinical Implications of Circulating Neurosteroids. Neuroactive Steroids and CNS Disorders. Neuroactive Steroids in Neuropsychopharmacology. Neurosteroids in the pharmacology and physiopathology of depression.


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© 2002
Academic Press
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