Neurosteroids and Brain Function - 1st Edition - ISBN: 9780123668462, 9780080544236

Neurosteroids and Brain Function, Volume 46

1st Edition

Serial Volume Editors: Giovanni Biggio Robert Purdy
Serial Editors: Ronald Bradley R. Adron Harris Peter Jenner
eBook ISBN: 9780080544236
Hardcover ISBN: 9780123668462
Imprint: Academic Press
Published Date: 27th September 2001
Page Count: 208
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Table of Contents

Neurosteroids: (Beginning of) The Story.
Biosynthesis of Neurosteroids and Regulation of their Synthesis.
Neurosteroid 7-hydroxylation Products in Brain.
Analysis of neurosteroids.
Role of Peripheral-Type Benzodiazepine Receptors in Adrenal and Brain Steroidogenesis.
Formation and Effects of Neuroactive Steroids in the Central and Peripheral Nervous System.
Neurosteroids and GABAA receptor function.
GABAA Receptor Plasticity During Long-Term Exposure to and Withdrawal From Progesterone.
Stress and Neuroactive Steroids.
Neurosteroids in learning and memory processes.
Neurosteroids and behaviour.
Ethanol and Neurosteroid Interactions in Brain.
Preclinical Development of Neurosteroids as Neuroprotective Agents for the Treatment of Neurodegenerative Diseases.
Clinical Implications of Circulating Neurosteroids.
Neuroactive Steroids and CNS Disorders.
Neuroactive Steroids in Neuropsychopharmacology.
Neurosteroids in the pharmacology and physiopathology of depression


International Review of Neurobiology, Volume 46 presents in-depth reviews on such ground-breaking topics as assembly and intracellular trafficking of GABA A receptors, D-1 dopamine receptors, and Alzheimer's disease. This series offers the most comprehensive and up-to-date information available and is a must for anyone in the field.

Key Features

  • Includes a historical overview of neurosteroid research
  • Contains a chapter on neurosteroid biosynthesis and regulation
  • Presents current methods of neurosteroid measurement and analysis
  • Discusses neurosteroid function in both the normal and the pathological brain
  • Chapters address the function of neurosteroid in: Stress, Receptor plasticity and function, Learning and Memory, Alcohol use, Depression


Researchers and graduate students in neuroscience, cell genetics, pharmacology, biology, and physiology


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© Academic Press 2002
Academic Press
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Ratings and Reviews

About the Serial Volume Editors

Giovanni Biggio Serial Volume Editor

Robert Purdy Serial Volume Editor

About the Serial Editors

Ronald Bradley Serial Editor

Affiliations and Expertise

Louisiana State University Medical Center, School of Medicine, Baton Rouge, U.S.A.

R. Adron Harris Serial Editor

Affiliations and Expertise

University of Texas, USA

Peter Jenner Serial Editor

Affiliations and Expertise

King's College, London, UK and Head of Pharmacology and Therapeutics Division