This hundredth volume is a commemorative milestone in the prestigeous Progress in Brain Research series. Accordingly, authors were invited to write on any topic, given that their choice represented the topic most near and dear to their own efforts over a significant period of the recent past, and to which they would likely continue to be devoted in the future.

In that sense, this volume does not represent a scientific meeting, but rather an overview sample of problems and methodologies that epitomize brain research broadly at this special moment in the maturation of the field.

The chapters comprising this volume assort themselves readily into five or six established categories of topics: developmental brain research, molecular brain research, integrative brain research, neuroplasticity, and neuro-psychiatric conditions.

This volume reports through a sample of recognized leaders in the neuroscientific community at a significant instant in the history and evolution of the field.

Table of Contents

Section I - Developmental Brain Research. 1. Cell migrations and establishment of neural connections in the developing brain: a study using the quail-chick chimera system. (N.M. Le Douarin, M.E.R. Hallonet, O. Pourquie). 2. Development of sympathetic neurons: neurotransmitter plasticity and differentiation factors (S.C. Landis). 3. Lessons from genetic knock-out mice deficient in neural recognition molecules (M. Schachner). Section II - Molecular Brain Research. 4. Quantitative analysis of neuronal gene expression (J.L. Roberts). 5. Molecular pharmacology of NMDA receptors: modulatory role of NR2 subunits (P.B. Molinoff, K. Williams, D.B. Pritchett, J. Zhong). 6. Glutamate receptors and the induction of excitotoxic neuronal death (D.W. Choi). 7. Sodium/potassium-coupled glutamate transporters, a "new" family of eukaryotic proteins: do they have "new" physiological roles and could they be new targets for pharmacological intervention? (N.C. Danbolt, J. Storm-Mathisen, O.P. Ottersen). 8. GABAC receptors (G.A.R. Johnston). 9. The central cholinergic system during aging (G. Pepeu, L. Giovannelli). 10. Co-existence of chemical messengers in neurons (G. Jaim-Etcheverry). 11. Cloning of kappa opioid receptors: functional significance and future directions (H. Akil, S.J. Watson). 12. Vasoactive intestinal peptide and noradrenaline regulate energy metabolism in astrocytes: a physiological function in the control of local homeostasis within the CNS (P.J. Magistretti). Section III - Integrative Brain Research 13. Segmental and descending control of the synaptic effectiveness of muscle afferents (P. Rudomin). 14. Noradrenergic control of cerebello-vestibular functions: modulation, adaptation, compensation (O. Pompeiano). 15 Chemical transmission in the brain: homeostatic regulation and its functional implications (M.J. Zigmond). 16. Conservation of basic synaptic circuits that mediate GABA inhibition in the subcortica


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© 1994
Elsevier Science
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About the editor

Floyd Bloom

Floyd Bloom was the editor of Science magazine, now Brain Research.