Neurophysiology in Neurosurgery - 2nd Edition - ISBN: 9780128150009

Neurophysiology in Neurosurgery

2nd Edition

A Modern Approach

Editors: Vedran Deletis Jay Shils Francesco Sala Kathleen Seidel
Hardcover ISBN: 9780128150009
Imprint: Academic Press
Published Date: 15th January 2020
Page Count: 500
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Neurophysiology in Neurosurgery: A Modern Approach, Second Edition, provides updates on the original techniques and overall methodology used in neuromonitoring. The purpose of this book is to describe the integration of neuromonitoring with surgical procedures. Each methodology is discussed in detail, along with chapters that describe how those methodologies are applied to multiple neurosurgical procedures and the evidence used to support those uses. The second edition features surgical procedures section, which focuses on specific surgical procedures and the type of monitoring used during these procedures.

The book's original chapters have been updated and expanded, with the structure modified to ensure the book is beneficial to both physiologists and surgeons. This book is written for neurosurgeons, neurophysiologists, neurologists, anesthesiologists, interventional neuroradiologists, orthopedic surgeons and plastic surgeons.

Key Features

  • Provides a valuable educational tool that describes the theoretical and practical aspects of intraoperative monitoring through example
  • Presents in-depth descriptions of the most advanced techniques in intraoperative neurophysiological monitoring, along with guidelines for the management of neuroanesthesia during MEP monitoring
  • Features a surgical procedures section that focuses on specific surgical procedures and the type of monitoring used during these procedures


Neurosurgeons, neurophysiologists, neurologists, anesthesiologists, interventional neuroradiologists, orthopedic surgeons, and plastic surgeons

Table of Contents

PART I: Introduction to Intraoperative Neurophysiology
a. Historical perspective

PART II: Intraoperative Neurophysiology: Neurophysiological perspective
a. Neurophysiology of the motor system: basics and IOM techniques
b. Neurophysiology of the somatosensory system: basics and IOM techniques
c. Neurophysiology of the auditory system: basics and IOM techniques
d. Neurophysiology of the visual system: basics and IOM techniques
e. Neurophysiology of language and other cognitive systems
f. Neurophysiology of critical brainstem and spine reflexes

PART III: Safety and Anesthesia in Intraoperative Neurophysiology
a. Safety
b. Principles of Anesthesia

PART IV: Intraoperative Neurophysiology: Surgical perspective
a. Supratentorial surgery
b. Infratentorial surgery
c. Spine and Spinal Cord Surgery
d. Surgery of the Peripheral Nervous System
e. Vascular Neurosurgery
f. Functional Neurosurgery

Part V: Conclusions on current challenges of neuromonitoring
a. Analysis of Costs and Benefits
b. Evidence Based Medicine and Intraoperative Neurophysiology
c. Current trends and threats


No. of pages:
© Academic Press 2020
15th January 2020
Academic Press
Hardcover ISBN:

About the Editor

Vedran Deletis

Vedran Deletis, MD, PhD is the former Director of the Intraoperative Neurophysiology Department in St. Luke’s/Roosevelt Hospital and an Associate Professor at the Albert Einstein College of Medicine in New York. Dr. Deletis is the founder of the International Society for Intraoperative Neurophysiology (ISIN) and served as its first president. Afar he completed his doctoral thesis in Clinical Neurophysiology and for the last 25 years he has dedicated his career to the field of Intraoperative Neurophysiology (ION). He established a fellowship program for ION in New York in which so far 20 fellows have participated, and have successfully implemented their acquired knowledge and experience in their respective countries. He has published numerous papers in the basic field of ION, especially on ION of the motor system.

Affiliations and Expertise

Department of Intraoperative Neurophysiology, Mount Sinai West Hospital, NY, USA

Jay Shils

Jay Shils

Jay L. Shils, Ph.D., D.ABNM, FASNM, FACNS is currently the director of intraoperative neurophysiological monitoring at Rush University Medical School and an Associate Professor in the department of Anesthesiology at Rush Medical Center. He received his Bachelor of Science degree in electrical engineering from Syracuse University, and both his masters and PhD in Bio-Engineering at The University of Pennsylvania using with his thesis dissertation subject – “The Bispectrum of the Human Electroencephalogram” to investigate interactions in the visual system and study EEG in epilepsy. Dr. Shils has been involved in intraoperative neuromonitoring since 1994 specializing in microelectrode neurophysiology for movement disorders. Dr. Shils is the co-editor of two neuromodulation related books which is one of his primary interests and the first edition of this book. Dr, Shils is a past president of the ASNM and the ISIN and is the founding secretary of the ISIN. Dr. Shils is the present secretary of the ASNM. Over the years Dr. Shils has presented at over 100 national and international has published on MER, DBS, neuromodulation, and intraoperative monitoring techniques.

Affiliations and Expertise

Director of Intraoperative Neurophysiological Monitoring and Associate Professor in Anesthesiology, Rush University Medical Center, Chicago, IL, USA

Francesco Sala

Dr. Francesco Sala is Assistant Professor of Neurosurgery at the Department of Neurological Sciences and Movement of the University of Verona. Following a fellowship in Pediatric Neurosurgery at the Hospital for Sick Children in Toronto, since 2009 he is Responsible for the Pediatric Neurosurgery Unit at the Institute of Neurosurgery in Verona. He has been an Executive Board member for the European Society for Pediatric Neurosurgery and the International Society for Pediatric Neurosurgery. Dr. Sala has been a co-founder of the International Society for Intraoperative Neurophysiology (ISIN), where he has served as Secretary (2009-2011), Chair of the Educational Committee (2010-2013) and President (2013-2015).

Affiliations and Expertise

Assistant Professor, Neurosurgery, Department of Neurological Sciences and Movement, University of Verona, Verona, Italy

Kathleen Seidel

Kathleen Seidel has established the unit of intraoperative neurophysiology at the department of neurosurgery and orthopaedics at the Inselspital University Hospital Bern Switzerland. Nowadays, Bern is hosting international observers and Kathleen Seidel is a routinely invited speaker in intraoperative neuromonitoring courses and congresses. She started to be active part in the society of intraoperative neurophysiology ISIN. Her future perspective is to strengthen the field of IOM and to provide advanced training to technicians and physicians as well as to focus on improvement in IOM modalities to improve patient safety in technical advanced high-risk surgeries. Her main research focus is monitoring and mapping techniques in supra- and infratentorial brain surgeries as well as awake surgeries. Kathleen Seidel completed her residency in neurosurgery and is since 2015 attending physician/ faculty in the department of neurosurgery at the Inselspital University Hospital Bern Switzerland. 2018 she received the Theodor Kocher Prize of the University Bern; 2019 she becomes associate professor of the University Hospital Bern.

Affiliations and Expertise

Head of the Unit of Intraoperative Neurophysiology. Attending Physician and Associate Professor, Neurosurgery, Inselspital, Bern University Hospital, Bern, Switzerland.

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