Neuromuscular Junction Disorders - 1st Edition - ISBN: 9780444520081, 9780080559872

Neuromuscular Junction Disorders, Volume 91

1st Edition

Editors: A. G. Engel
Hardcover ISBN: 9780444520081
eBook ISBN: 9780080559872
Imprint: Elsevier
Published Date: 4th August 2008
Page Count: 480
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Table of Contents

The most vulnerable synapse: historic aspects of neuromuscular junction disorders. Reliability of neuromuscular transmission and how it is maintained. The neuromuscular junction. Electromyographic aspects of neuromuscular junction disorders. The immunopathogenesis of myasthenia gravis. Autoantibodies in different forms of myasthenia gravis and in the Lambert-Eaton syndrome. Clinical features of myasthenia gravis. Therapy of myasthenia gravis. The Lambert-Eaton myasthenic syndrome. Congenital myasthenic syndromes. Botulism. Neurotoxicology of neuromuscular transmission. Organophosphate and carbamate poisoning. Peripheral nerve hyperexcitability and the neuromuscular junction.


Description

The most vulnerable synapse: historic aspects of neuromuscular junction disorders. Reliability of neuromuscular transmission and how it is maintained. The neuromuscular junction. Electromyographic aspects of neuromuscular junction disorders. The immunopathogenesis of myasthenia gravis. Autoantibodies in different forms of myasthenia gravis and in the Lambert-Eaton syndrome. Clinical features of myasthenia gravis. Therapy of myasthenia gravis. The Lambert-Eaton myasthenic syndrome. Congenital myasthenic syndromes. Botulism. Neurotoxicology of neuromuscular transmission. Organophosphate and carbamate poisoning. Peripheral nerve hyperexcitability and the neuromuscular junction.

Key Features

  • New insights into the study of neuromuscular junction disorders, including rapid advancements in the field
    Comprehensive information on the neuromuscular junction, and a detailed examination of myasthenia gravis and other disorders
    A new framework upon which to build therapeutic strategies that will enhance the restoration of normal function in neuromuscular disorders

Readership

Neurologists
Neuroscience research workers


Details

No. of pages:
480
Language:
English
Copyright:
© Elsevier 2008
Published:
Imprint:
Elsevier
eBook ISBN:
9780080559872
Hardcover ISBN:
9780444520081

About the Editors

A. G. Engel Editor

Affiliations and Expertise

William L McKnight Professor of Neuroscience, Mayo Clinic College of Medicine; Director, Neuromuscular Disease Research Laboraotry; Consultant Department of Neurology, Mayo Clinic, Rochester, MN, USA