Neuromodulation - 2nd Edition - ISBN: 9780128053539


2nd Edition

Comprehensive Textbook of Principles, Technologies, and Therapies

Editors: Elliot Krames P. Hunter Peckham Ali Rezai
Hardcover ISBN: 9780128053539
Imprint: Academic Press
Published Date: 1st November 2017
Page Count: 1250
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Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs.

The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine.

Key Features

  • Provides a comprehensive reference that covers all aspects of the growing field of neuromodulation
  • Written by international, leading authorities in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering
  • Includes new chapters on optogenetics, bioelectronics medicine and brain computer interfacing


Advanced graduate students, researchers, and clinicians in the fields of neuroscience, neurology, neurosurgery, psychiatry, and biomedical engineering

Table of Contents

Volume 1:
Section I: An Introduction to Neuromodulation
Section II: Fundamentals and Mechanisms of Neuromodulation
Section III: Technology and Devices
Section IV: Neuromodulation for Pain Control
Section IV A: Spinal Cord Stimulation for Pain Control
Section IV B: Peripheral Nerve Stimulation for Pain Control Introduction: Peripheral Nerve Stimulation for Pain Control
Section IV C: Intrathecal Therapies for Pain Control and the Control of Spasticity
Section IV D: Intracranial Procedures for Chronic Pain
Section V: Neuromodulation for Movement Disorders
Section VI: Neurostimulation for Epilepsy
Section VII: Neuromodulation for Behavioral and Cognitive Disorders

Volume 2:
Section VIII: Neuromodulation for Functional Restoration
Section IX: Neuromodulation for Organ Systems
Section IX A: Neuromodulation for Cardiovascular Disorders
Section IX B: Neuromodulation for Pulmonary Disorders
Section IX C: Neuromodulation for Gastrointestinal Disorders
Section IX D: Neuromodulation for Urogenital Disorders
Section X: Neuromodulation for Endocrine, Immune, and Inflammatory Disorders
Section XI: Brain, Computer and Machine Interfacing
Section XII: Non Invasive Neuromodulation
Section XIII: Surgical Procedures and Techniques
Section XIV: The Business end of Neuromodulation
Section XV: Emerging Technologies and Techniques
Section XVI: The Brain Initiative—Implications for a Revolutionary Change in Clinical Medicine via Neuromodulation Technology


No. of pages:
© Academic Press 2018
Academic Press
Hardcover ISBN:

About the Editor

Elliot Krames

Elliot S. Krames, MD, is a board-certified anesthesiologist who has been practicing pain medicine solely since 1987. He is a worldwide-recognized leader and educator in the field of neuromodulation for pain control. He has written extensively on implantable technologies for pain management and has conducted national and international symposia related to this topic. He is co-founder of the National Pain Foundation, a founding member of the North American Neuromodulation Society and has participated on the boards of the North American Neuromodulation Society, the International Neuromodulation Society, the World Institute of Pain, the American Academy of Pain Medicine, and the American Board of Pain Medicine. Dr. Krames has published more than 100 research papers, serves on several editorial boards, and co-edited a number of books. Dr. Krames was the founding editor of Neuromodulation: Technology at the Neural Interface, the journal of the International Neuromodulation Society, serving as Editor-in-Chief from 1998 until September 2009, when he became Emeritus Editor-in-Chief. Dr. Krames served as INS President from 2006 to 2009, as immediate Past President from 2009 to 2011, and since 2011 has been Emeritus Director-at-Large.

Affiliations and Expertise

Pacific Pain Treatment Center, San Francisco, CA, USA

P. Hunter Peckham

Dr. Peckham is the Donnell Institute Professor of Biomedical Engineering and Orthopaedics at Case Western Reserve University and Director, Cleveland Functional Electrical Stimulation Center. The major area of Dr. Peckham's research is in rehabilitation engineering and neuroprostheses. He’s also the Founder for the Institute for Functional Restoration at the Case Western School of Medicine and the Co-Director of MetroHealth Rehabilitation Institute of Ohio. A holder of eight patents, he is a member of multiple councils, Dr. Peckham is also a fellow of the American Institute of Medical and Biological Engineering.

Affiliations and Expertise

Case Western Reserve University, Cleveland, OH, USA

Ali Rezai

Dr. Rezai is currently Associate Dean of Neuroscience and the Director of the Neurological Institute at OSU. Dr. Rezai has published over 150 peer reviewed articles, more than 30 book chapters, and serves on the editorial board of five journals. Dr. Rezai is currently the Past President of the Congress of Neurological Surgeons (CNS), the largest neurosurgical societies in the world, as well as the Past President North American Neuromodulation Society (NANS), and the American Society of Stereotactic and Functional Neurosurgery (ASSFN).Dr. Rezai’s research focuses on mechanisms of neurostimulation, and developing neuromodulation devices and novel therapeutic strategies for treatment of neurological disorders.

Affiliations and Expertise

The Ohio State University Wexner Medical Center, Columbus OH, USA