Neurology of Vision and Visual Disorders

Neurology of Vision and Visual Disorders

1st Edition - April 6, 2021

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  • Editors: Jason Barton, Alexander Leff
  • Hardcover ISBN: 9780128213773
  • eBook ISBN: 9780128213780

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Neurology of Vision and Visual Disorders, Volume 178 in the Handbooks of Neurology series provides comprehensive summaries of recent research on the brain and nervous system. This volume reviews alterations in vision that stem from the retina to the cortex. Coverage includes content on vision and driving derived from the large amount of time devoted in clinics to determining who is safe to drive, along with research on the interplay between visual loss, attention and strategic compensations that may determine driving suitability. The title concludes with vision therapies and the evidence behind these approaches. Each chapter is co-written by a basic scientist collaborating with a clinician to provide a solid underpinning of the mechanisms behind the clinical syndromes.

Key Features

  • Reviews the neurological underpinnings of visual perception disorders
  • Encompasses the cortex to the retina
  • Covers functional organization, electrophysiology and subcortical visual pathways
  • Discusses assessment, diagnosis and management of visual perception disorders
  • Includes international experts from Australia, Canada, Denmark, Germany, Singapore, and the UK and US


Clinical neurologists, researchers in neurology ophthalmologists

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Handbook of Clinical Neurology 3rd Series
  • Foreword
  • Preface
  • Contributors
  • Chapter 1: A review of diseases of the retina for neurologists
  • Abstract
  • Introduction
  • Retina Anatomy
  • Retinal Disorders With Acute Presentations
  • Acute or Chronic Presentation
  • Chronic Presentation
  • Chapter 2: Amblyopia
  • Abstract
  • Introduction
  • Clinical Diagnosis
  • Behavioral and Neural Consequences
  • Treatment
  • Experimental Treatments: Targets, Mechanisms, and Future Directions
  • Chapter 3: Retinal ganglion cells and the magnocellular, parvocellular, and koniocellular subcortical visual pathways from the eye to the brain
  • Abstract
  • The Standard Model of Early Visual Function
  • Perceptual Correlates of Subcortical Pathways
  • Conclusion
  • Chapter 4: Perimetry and visual field defects
  • Abstract
  • Introduction
  • Types of Perimetric Testing
  • The Psychophysics of Perimetry
  • Interpreting Perimetry Results
  • Future Directions
  • Conclusions
  • Chapter 5: Electrophysiology in neuro-ophthalmology
  • Abstract
  • Introduction
  • Electrophysiological Tests of the Visual System
  • Optic Neuropathies and Central Nervous System Disorders
  • Retinal masqueraders of optic neuropathy
  • Summary
  • Acknowledgments
  • Chapter 6: The role of optical coherence tomography in the diagnosis of afferent visual pathway problems: A neuroophthalmic perspective
  • Abstract
  • Optical Coherence Tomography: Key Concepts
  • Optical Coherence Tomography in the Evaluation of Optic Neuropathies: Applying Principles to Practice
  • Lesions of the Posterior Visual Pathways
  • Retinal Disorders Masquerading as Optic Nerve Lesions
  • Conclusions
  • Chapter 7: The striate cortex and hemianopia
  • Abstract
  • Introduction
  • The Acknowledged Functions of V1
  • The Role of Visual Inputs That Bypass V1
  • Evidence From Area V5 About the Role of V1 in Conscious Vision
  • The Riddoch Syndrome and Blindsight
  • V1 and the Conscious Experience of the Visual World
  • V1 and Conscious Visual Experience
  • Are Pre- and Postprocessing by V1 Essential for Visual Consciousness?
  • Conclusion
  • History of the Cortical Representation of the Visual Field
  • Linear Cortical Magnification Factor (M)
  • Patterns of Hemifield Disturbance
  • Unusual Patterns of Partial Homonymous Hemifield Loss
  • Acknowledgment
  • Chapter 8: Color vision
  • Abstract
  • What Is Color Vision for?
  • Retinal Mechanisms for Human Color Vision
  • Postreceptoral Mechanisms for Color: Theory and Implementation
  • Inherited Color Vision Defects
  • Acquired Color Vision Defects
  • Diagnosing Color Vision Defects
  • Chapter 9: Object recognition and visual object agnosia
  • Abstract
  • Introduction
  • Visual Object Recognition and Its Neural Correlates
  • Types of Visual Agnosia
  • Related Disorders
  • Neuropathology and Prevalence of Visual Object Agnosia
  • Clinical Assessment
  • Chapter 10: Prosopagnosia and disorders of face processing
  • Abstract
  • Diagnosing Prosopagnosia
  • Functional Variants of Prosopagnosia
  • The Lesions of Acquired Prosopagnosia
  • Neuroimaging in Developmental Prosopagnosia
  • The Specificity of Prosopagnosia for Faces
  • Covert Face Recognition
  • Other Clinical Signs and Disorders Associated With Prosopagnosia
  • Treatment of Prosopagnosia
  • Other Disorders Affecting Aspects of Face Perception Besides Identity
  • Conclusion
  • Acknowledgments
  • Chapter 11: The relationship between mental and physical space and its impact on topographical disorientation
  • Abstract
  • Introduction
  • How Do We Know Mental Space's Properties?
  • Properties of Mental Space
  • The Brain's Representations of Space
  • Space Processing in Acquired and Developmental Topographical Disorientation
  • Conclusions
  • Acknowledgments
  • Chapter 12: Reading and alexia
  • Abstract
  • Introduction
  • Neuroanatomy of Reading
  • The Peripheral Alexias
  • Reading Assessment
  • Chapter 13: Bálint syndrome
  • Abstract
  • Initial Observations
  • Historical Reports and Interpretation of Visuomotor Clumsiness
  • Visuomotor Clumsiness: A Deficit of Simultaneous Location Processing?
  • Historical Descriptions and Interpretation of Ocular and Perceptual/Attentional Deficits
  • Simultanagnosia/Extinction: A Deficit of Simultaneous Location Processing?
  • A Renewed Model of PPC Organization
  • Hemineglect: Included or Not Included in the Syndrome?
  • Clinical Testing for the Key Symptoms of Bálint Syndrome
  • Conclusion
  • Chapter 14: Motion perception and its disorders
  • Abstract
  • Varieties of Motion Phenomena and Stimuli
  • Response Properties of Neurons in Motion-Selective Areas in Nonhuman Primates
  • Lesion and Stimulation Studies of Motion-Selective Areas in Nonhuman Primates
  • Functional Studies of Motion Perception in Humans
  • Cerebral Akinetopsia: Cases LM and AF
  • Other Patients With Motion Perception Deficits From Focal Cerebral Lesions
  • Recovery and Treatment
  • Motion Perception and Other Neurologic Conditions
  • Pediatric Cerebral Syndromes With Impaired Motion Perception
  • Conclusions
  • Appendix: Online video demonstrations of various motion stimuli
  • Chapter 15: Aphantasia: The science of visual imagery extremes
  • Abstract
  • Visual Imagery
  • Extremes of Visual Imagery
  • Implications and Unanswered Questions
  • Chapter 16: Blindsight
  • Abstract
  • Introduction
  • Controversy
  • The Taxonomy of Blindsight
  • The Various Phenomena of Blindsight
  • Dissociations
  • Residual Visual Pathways
  • Implications
  • Acknowledgments
  • Chapter 17: Illusions, hallucinations, and visual snow
  • Abstract
  • Introduction
  • Definitions
  • Illusions
  • Hallucinations
  • Ophthalmic Causes of Illusions and Hallucinations
  • Palinopsia and polyopia
  • Disease-Specific Disorders
  • Syndromic Disorders
  • Conclusion
  • Chapter 18: Vision, attention, and driving
  • Abstract
  • Introduction
  • Motor Vehicle Driving
  • Theoretical Framework
  • Diseases of the Eye
  • Diseases of the Brain
  • Compensatory Technologies
  • Conclusions
  • Chapter 19: Rehabilitation of visual disorders
  • Abstract
  • Introduction
  • Rehabilitation of Visual Symptoms in Patients With Mild Traumatic Brain Injury
  • Rehabilitation of Hemianopia
  • Rehabilitation of Alexia
  • Prosopagnosia
  • Index

Product details

  • No. of pages: 410
  • Language: English
  • Copyright: © Elsevier 2021
  • Published: April 6, 2021
  • Imprint: Elsevier
  • Hardcover ISBN: 9780128213773
  • eBook ISBN: 9780128213780

About the Series Volume Editors

Jason Barton

Jason Barton obtained his MD from the University of British Columbia in 1984, where he completed a neurology residency in 1990. He was a fellow in neuro-ophthalmology at the University of Iowa from 1990 to 1991 and the University of Toronto from 1991 to 1995, and obtained his PhD from the University of Toronto in 1996. He was assistant and then associate professor of neurology at Harvard Medical School, and director of neuro-ophthalmology at the Beth Israel Deaconess Medical Center from 1996 to 2004. Since 2004 he has been director of clinical neuro-ophthalmology at Vancouver General Hospital. He is currently professor, Canada Research Chair and Marianne Koerner Chair in Brain Diseases, in neurology, ophthalmology and visual sciences, and psychology at the University of British Columbia. His research is focused on cortical processing of vision, in particular high-level object perception, such as face and word recognition, and also on the use of saccadic eye movements to explore issues of cognitive control.

Affiliations and Expertise

Professor, Canada Research Chair, Marianne Koerner Chair of Brain Diseases, Departments of Medicine (Neurology), Ophthalmology and Visual Sciences, Psychology, University of British Columbia, and Director of Neuro-Ophthalmology and Human Vision and Eye Movement Laboratory, VGH Eye Care Centre, Vancouver, British Columbia, Canada

Alexander Leff

I am Professor of Cognitive Neurology and a Consultant Neurologist at the UCL Queen Square Institute of Neurology. My main clinical and academic interest is in cognitive rehabilitation, especially in the field of acquired language disorders and vision. I am developing mechanistic accounts of how cognitive disorders can be improved by different types of therapy -mainly behavioural- using functional and structural brain imaging. I have developed three web-based rehabilitation tools that can be used to by therapists and patients with hemianopia or reading problems, and am working on four other electronic therapy projects sponsored by the MRC, NIHR and The Stroke Association. I think that web-based applications are a good way to make scientifically proven behavioural therapies available to suitable patients and their therapists. At the UCLH National Hospital for Neurology and Neurosurgery I have a specialist out-patient MDT assessment clinic for patients with hemianopia and/or higher disorders of vision. I also help run the Queen Square Intensive Comprehensive Aphasia Programme. Publications Academic website

Affiliations and Expertise

University College London Hospitals, NHS Foundation Trust, National Hospital for Neurology and Neurosurgery, London, UK

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