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Neurological Modulation of Sleep - 1st Edition - ISBN: 9780128166581, 9780128166598

Neurological Modulation of Sleep

1st Edition

Mechanisms and Function of Sleep Health

Editors: Ronald Watson Victor Preedy
Paperback ISBN: 9780128166581
eBook ISBN: 9780128166598
Imprint: Academic Press
Published Date: 16th January 2020
Page Count: 430
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Neurological Modulation of Sleep provides readers with updated scientific reviews regarding the interaction between sleep and contributing factors, with special attention paid to the potential for neurological modulation of sleep via diet. This book expands the notion of diet and adds an element of physical activity and exercise as well as a chapter on caffeine and its effects on sleep. With 30+ international contributors, this book aims to provide readers with a unique global perspective on the role these factors plays in sleep architecture and its regulation by circadian biology and neurology.

Sleep disorders have become an increasing problem plaguing more than 70 million Americans according to the American Sleep Association. There is a clear association between sleep disorder and a wide range of other human disorders –performance deficiencies, psychiatric illnesses, heart disease, obesity and more – but in spite of this there is not yet a convenient overview on the market detailing the impact of obesity, age, diabetes and diet on sleep duration and attendant health outcomes.

Key Features

  • Describes the impact of diet, caffeine and physical activity on sleep
  • Reviews the neurology and metabolism of sleep
  • Identifies what foods impact sleep and how
  • Discusses the clinical use of nutraceuticals to improve sleep


Nutritionists, government regulators of food, and Food Scientists interested in the specific health benefits of various agents to modify sleep.  Nutritionists and Food Scientists interested in the specific health benefits

Table of Contents

1. Diet, Age, and Sleep in Invertebrate Model Organisms
2. The Role of Sleep in the Control of Feeding Behavior
3. Diagnosis and Treatment of Shift Work Disorder
4. Normal Sleep and Its Neurophysiological Regulation
5. The 1-2-3s of Pediatric Sleep Disorders
6. Sleep Disturbances, Body Mass Index, and Eating Behavior
7. Neurocognitive Functions in Patients with Obstructive Sleep Apnea Hypopnea Syndrome
8. Adipose Tissue in Sleep Apnea: Effects of Hypoxia and Inflammation
9. Exercise, Diet, and Obese Adolescents: Association with Sleep Deprivation
10. Sleep and Hypoxemia in Adults
11. Obesity Hypoventilation Syndrome
12. Sleep, Sexual Function, and Testosterone
13. The Malignant Obesity Hypoventilation Syndrome
14. Obesity, Inflammation, and Obstructive Sleep Apnea: Exercise as Therapy
15. Obstructive Sleep Apnea in Normal-Weight and Obese Patients
16. Obstructive Sleep Apnea and the Metabolic Syndrome: Clinical Profiles and Relationships
17. Circadian Misalignment and Metabolic Consequences: Shiftwork and Altered Meal Times
18. Role of Sympathetic Nervous System in the Metabolic Syndrome and Sleep Apnea
19. Obstructive Sleep Apnea and the Metabolic Syndrome: Pathophysiological and Clinical Evidence
20. Sleep Deprivation and Metabolic Syndrome
21. Excessive Daytime Sleepiness: Age, Sleep, Mood, and Metabolic Modulation
22. The Metabolic Role of Saturated and Monounsaturated Dietary Fatty Acids: Their Contribution to Obesity, Brain Activity, and Sleep Behavior
23. Obstructive Sleep Apnea and Diabetic Microvascular Complications
24. Obstructive Sleep Apnea Increases Hemoglobin A1c Levels: Mechanisms and Consequences
25. Restless Legs Syndrome (Willis–Ekbom Disease) and Gastrointestinal Diseases
26. Relationship between Circadian Rhythms, Feeding, and Obesity
27. The Effects of Nutrition on Sleep and Sleep Complaints among Elderly Persons
28. Fragmented Sleep and Memory Consolidation
29. Sleepiness at the Wheel and Countermeasures: Effects of Caffeine, Napping, and Blue Light
30. Sleep Deprivation and Behavioral Risk-Taking
31. Relation between Magnesium Deficiency and Sleep Disorders and Associated Pathological Changes
32. Physical Activity and Sedentary Time in Sleep Apnea and Obesity
33. Oxidative Stress in Sleep Apnea
34. Sleep in Fetal Alcohol Spectrum Disorders
35. Adenosine and Glutamate in Neuroglial Interaction: Implications for Sleep Disorders and Alcoholism
36. Sleep Quality and Risk of Alcohol Misuse
37. Sleep and Addictions: Linking Sleep Regulation with the Genesis of Addictive Behavior
38. Alcohol and Sleep-Disordered Breathing
39. Patterns of Alcohol Consumption and Sleep in Shiftworkers
40. The Impact of Bariatric Surgery on Obstructive Sleep Apnea
41. Preoperative, Perioperative, and Postoperative Considerations in the Bariatric Surgery Patient with Sleep Apnea


No. of pages:
© Academic Press 2020
16th January 2020
Academic Press
Paperback ISBN:
eBook ISBN:

About the Editors

Ronald Watson

Ronald Watson

Ronald Ross Watson, PhD, is Professor of Health Promotion Sciences at the University of Arizona, Mel and Enid Zuckerman College of Public Health. Dr. Watson began his research in public health at the Harvard School of Public Health as a Fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia and the United States which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring as a Lt. Colonel. He is a distinguished member of several national and international nutrition, immunology, and cancer societies. Dr. Watson’s career has involved studying many lifestyle aspects for their uses in health promotion. He has edited over 100 biomedical reference books and 450 papers and chapters. His teaching and research focuses on alcohol, tobacco, and drugs of abuse in heart function and disease in mouse models.

Affiliations and Expertise

Professor, Mel and Enid Zuckerman College of Public Health and School of Medicine, Arizona Health Sciences Center, University of Arizona, Tucson, AZ, USA

Victor Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

Affiliations and Expertise

Professor of Nutritional Biochemistry, Department of Nutrition and Dietetics, Professor of Clinical Biochemistry, Department of Clinical Biochemistry; Director of the Genomics Centre, King’s College, London, UK

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