Neurological Modulation of Sleep

Neurological Modulation of Sleep

Mechanisms and Function of Sleep Health

1st Edition - January 15, 2020

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  • Editors: Ronald Ross Watson, Victor Preedy
  • eBook ISBN: 9780128166598
  • Paperback ISBN: 9780128166581

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Neurological Modulation of Sleep provides readers with updated scientific reviews regarding the interaction between sleep and contributing factors, with special attention paid to the potential for neurological modulation of sleep via diet. This book expands the notion of diet and adds an element of physical activity and exercise as well as a chapter on caffeine and its effects on sleep. With 30+ international contributors, this book aims to provide readers with a unique global perspective on the role these factors plays in sleep architecture and its regulation by circadian biology and neurology. Sleep disorders have become an increasing problem plaguing more than 70 million Americans according to the American Sleep Association. There is a clear association between sleep disorder and a wide range of other human disorders –performance deficiencies, psychiatric illnesses, heart disease, obesity and more – but in spite of this there is not yet a convenient overview on the market detailing the impact of obesity, age, diabetes and diet on sleep duration and attendant health outcomes.

Key Features

  • Describes the impact of diet, caffeine and physical activity on sleep
  • Reviews the neurology and metabolism of sleep
  • Identifies what foods impact sleep and how
  • Discusses the clinical use of nutraceuticals to improve sleep


Nutritionists, government regulators of food, and Food Scientists interested in the specific health benefits of various agents to modify sleep.  Nutritionists and Food Scientists interested in the specific health benefits

Table of Contents

  • 1. Diet, Age, and Sleep in Invertebrate Model Organisms
    2. The Role of Sleep in the Control of Feeding Behavior
    3. Diagnosis and Treatment of Shift Work Disorder
    4. Normal Sleep and Its Neurophysiological Regulation
    5. The 1-2-3s of Pediatric Sleep Disorders
    6. Sleep Disturbances, Body Mass Index, and Eating Behavior
    7. Neurocognitive Functions in Patients with Obstructive Sleep Apnea Hypopnea Syndrome
    8. Adipose Tissue in Sleep Apnea: Effects of Hypoxia and Inflammation
    9. Exercise, Diet, and Obese Adolescents: Association with Sleep Deprivation
    10. Sleep and Hypoxemia in Adults
    11. Obesity Hypoventilation Syndrome
    12. Sleep, Sexual Function, and Testosterone
    13. The Malignant Obesity Hypoventilation Syndrome
    14. Obesity, Inflammation, and Obstructive Sleep Apnea: Exercise as Therapy
    15. Obstructive Sleep Apnea in Normal-Weight and Obese Patients
    16. Obstructive Sleep Apnea and the Metabolic Syndrome: Clinical Profiles and Relationships
    17. Circadian Misalignment and Metabolic Consequences: Shiftwork and Altered Meal Times
    18. Role of Sympathetic Nervous System in the Metabolic Syndrome and Sleep Apnea
    19. Obstructive Sleep Apnea and the Metabolic Syndrome: Pathophysiological and Clinical Evidence
    20. Sleep Deprivation and Metabolic Syndrome
    21. Excessive Daytime Sleepiness: Age, Sleep, Mood, and Metabolic Modulation
    22. The Metabolic Role of Saturated and Monounsaturated Dietary Fatty Acids: Their Contribution to Obesity, Brain Activity, and Sleep Behavior
    23. Obstructive Sleep Apnea and Diabetic Microvascular Complications
    24. Obstructive Sleep Apnea Increases Hemoglobin A1c Levels: Mechanisms and Consequences
    25. Restless Legs Syndrome (Willis–Ekbom Disease) and Gastrointestinal Diseases
    26. Relationship between Circadian Rhythms, Feeding, and Obesity
    27. The Effects of Nutrition on Sleep and Sleep Complaints among Elderly Persons
    28. Fragmented Sleep and Memory Consolidation
    29. Sleepiness at the Wheel and Countermeasures: Effects of Caffeine, Napping, and Blue Light
    30. Sleep Deprivation and Behavioral Risk-Taking
    31. Relation between Magnesium Deficiency and Sleep Disorders and Associated Pathological Changes
    32. Physical Activity and Sedentary Time in Sleep Apnea and Obesity
    33. Oxidative Stress in Sleep Apnea
    34. Sleep in Fetal Alcohol Spectrum Disorders
    35. Adenosine and Glutamate in Neuroglial Interaction: Implications for Sleep Disorders and Alcoholism
    36. Sleep Quality and Risk of Alcohol Misuse
    37. Sleep and Addictions: Linking Sleep Regulation with the Genesis of Addictive Behavior
    38. Alcohol and Sleep-Disordered Breathing
    39. Patterns of Alcohol Consumption and Sleep in Shiftworkers
    40. The Impact of Bariatric Surgery on Obstructive Sleep Apnea
    41. Preoperative, Perioperative, and Postoperative Considerations in the Bariatric Surgery Patient with Sleep Apnea

Product details

  • No. of pages: 430
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: January 15, 2020
  • Imprint: Academic Press
  • eBook ISBN: 9780128166598
  • Paperback ISBN: 9780128166581

About the Editors

Ronald Ross Watson

Ronald Ross Watson
Ronald Ross Watson, PhD, is Professor of Health Promotion Sciences at the University of Arizona, Mel and Enid Zuckerman College of Public Health. Dr. Watson began his research in public health at the Harvard School of Public Health as a Fellow in 1971 doing field work on vaccines in Saudi Arabia. He has done clinical studies in Colombia, Iran, Egypt, Saudi Arabia and the United States which provides a broad international view of public health. He has served in the military reserve hospital for 17 years with extensive training in medical responses to disasters as the chief biochemistry officer of a general hospital, retiring as a Lt. Colonel. He is a distinguished member of several national and international nutrition, immunology, and cancer societies. Dr. Watson’s career has involved studying many lifestyle aspects for their uses in health promotion. He has edited over 100 biomedical reference books and 450 papers and chapters. His teaching and research focuses on alcohol, tobacco, and drugs of abuse in heart function and disease in mouse models.

Affiliations and Expertise

Professor, Mel and Enid Zuckerman College of Public Health and School of Medicine, Arizona Health Sciences Center, University of Arizona, Tucson, AZ, USA

Victor Preedy

Dr. Preedy is a senior member of King's College London and Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well-being. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is an extremely experienced book editor, having edited influential works including but not limited to The Handbook of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse, The Handbook of Cannabis and Related Pathologies, The Neuroscience of Cocaine, and upcoming titles The Neuroscience of Alcohol, The Neuroscience of Nicotine, and more (all Elsevier).

Affiliations and Expertise

Professor of Nutritional Biochemistry, Department of Nutrition and Dietetics, Professor of Clinical Biochemistry, Department of Clinical Biochemistry; Director of the Genomics Centre, King’s College, London, UK

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