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General Methods: C.H. Pontzer and H.M. Johnson, Measurement of Interferons. T.L. Whiteside and R.B. Herberman, Measurements of Natural Killer Cell Numbers and Function in Humans. R. Scicchitano, A. Wozniak,J. McNeil, S.J. Usher, and W.H. Betts, Functional Assays to Determine Effects of Mammalian Tachykinins on Human Neutrophils. E.P. Cowan and S.S. Dhib-Jalbut, Molecular Techniques for Detection of Gene Expression in Neuroimmunology. W.E. Winter, R.H. Buck, and D.A. Varga-House, Class I and Class II Major Histocompatibility Complex Molecules. A. Miadonna, M. Palella, M.P. DiMarco, and A. Tedeschi, In Vitro Immunoglobulin E-Mediated and -Independent Histamine Release from Human BasophilLeukocytes. M.E. Sales and E.S. Borda, Immunopharmacological Methods to Study Murine Allogeneic and Syngeneic Pregnancy. L.H. Elliott, S.L. Carlson, L.A. Morford, and J.P. McGillis, Preparation, Characterization, and Use of Human and Rodent Lymphocytes, Monocytes, and Neutrophils. R.J. Vandebriel, J. Garssen, and H. Van Loveren, Methods in Immunotoxicology. D.A. Halliday, J.D. McNeil, W.H. Betts, and R. Scicchitano, Effects of Tachykinins on Chondrocyte and Synoviocyte Function. The Brain Immune System: B.S. Rabin, M.A. Pezzone, A. Kusnecov, and G.E. Hoffman, Identification of Stressor-Activated Areas in the Central Nervous System. G.A. Belokrylov and E.I. Sorochinskaya, Methodological Approaches for Studying Neuroimmune Connection of Identical Functional Blocks. G.B. Stefano, Computer-Assisted Microscopic Image Analysis in Neuroimmunology. V.W. Yong and V. Balasingam, Cytokines as Mediators of Reactive Astrogliosis. H. Imboden and D. Felix, Immunocytochemistry in Brain Tissue. J. Dalmau and M.R. Rosenfeld, Characterization of Neuronal Antigens and Antineuronal Antibodies. W.J. Streit, A.G. Rabchevsky, D.P. Theele, and W.F. Hickey, Immunohistochemistry of Leukocyte Antigens in Rat Brain. Neuroimmune System: Effects of the Brain on the Peripheral Immune System: M.I. Phillips and L.D. Fannon, Measuring Immune Responses to Brain Manipulation in Rat. B.S. Zwilling, Methods in Neuroimmunomodulation of Macrophage Function. D.T. Lysle, Stressor-Induced Immune Alterations in Rodents. B.R. Darby and L.D. Fannon, Measurement of the Immune System in Response to Psychological Intervention. C.C. Maier and J.E. Blalock, Cloning and Sequencing Immunoglobulin and T-Cell Receptor Variable Regions Involved in Neuroimmune Disorders. S.L. Carson and J.P. McGillis, Modulation of Leukocyte Adhesion, Migration, and Homing by Neurotransmitters and Neuropeptides. J.P. McGillis, Neuropeptides as Immunomodulators: Measurements of Calcitonin Gene-Related Peptide Receptors in the Immune System. I.R. Tebbett and J. Karlix, Effects of Cocaine on the Immune Response. R.M. Donahoe, J.J. Madden, D.R. Oleson, and C.B. Nemeroff, Immunological, Pharmacological,and Electrophysiological Detection of T-Cell Modulation Properties of Substances of Abuse. Index.
The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike.
Comprehensive protocols included for the study of:
- The brain-immune system
- The neuroimmune system: Effects of the brain on the peripheral immune system
- Neuroimmune effects from substances of abuse (e.g. cocaine) to hypnosis
- Measurement of interferons, cytokines, natural killer cells, and major histocompatibility complex molecules
- Immunohistochemistry methods in the brain
- Neuropeptides as immunomodulators
Neuroimmunologists, immunologists, neuropharmacologists, neurophysiologists, neurochemists, biochemists, molecular biologists, and physiologists.
- No. of pages:
- © Academic Press 1995
- 18th January 1995
- Academic Press
- eBook ISBN:
"Well-written, clear and detailed... The authors do indeed offer the 'fine detail, tricks and short cuts not usually found in the written word." --TRENDS IN NEUROSCIENCES
P. Michael Conn is the Senior Vice President for Research and Associate Provost, Texas Tech Health Sciences Center. He is The Robert C. Kimbrough, Professor of Internal Medicine and Cell Biology/Biochemistry. He was previously Director of Research Advocacy and Professor of Physiology and Pharmacology, Cell Biology and Development and Obstetrics and Gynecology at Oregon Health and Science University and Senior Scientist of the Oregon National Primate Research Center (ONPRC). He served for twelve years as Special Assistant to the President and Associate Director of the ONPRC. After receiving a B.S. degree and teaching certification from the University of Michigan (1971), a M.S. from North Carolina State University (1973), and a Ph.D. degree from Baylor College of Medicine (1976), Conn did a fellowship at the NIH, then joined the faculty in the Department of Pharmacology, Duke University Medical Center where he was promoted to Associate Professor in 1982. In 1984, he became Professor and Head of Pharmacology at the University of Iowa College of Medicine, a position he held for eleven years. Conn is known for his research in the area of the cellular and molecular basis of action of gonadotropin releasing hormone action in the pituitary and therapeutic approaches that restore misfolded proteins to function. His work has led to drugs that have benefitted humans and animals. Most recently, he has identified a new class of drugs, pharmacoperones, which act by regulating the intracellular trafficking of receptors, enzymes and ion channels. He has authored or co-authored over 350 publications in this area and written or edited over 200 books, including texts in neurosciences, molecular biology and endocrinology. Conn has served as the editor of many professional journals and book series (Endocrinology, Journal of Clinical Endocrinology and Metabolism, Endocrine, Methods, Progress in Molecular Biology and Translational Science and Contemporary Endocrinology). Conn served on the National Board of Medical Examiners, including two years as chairman of the reproduction and endocrinology committee. The work of his laboratory has been recognized with a MERIT award from the NIH, the J.J. Abel Award of the American Society for Pharmacology and Experimental Therapeutics, the Weitzman, Oppenheimer and Ingbar Awards of the Endocrine Society, the National Science Medal of Mexico (the Miguel Aleman Prize) and the Stevenson Award of Canada. He is the recipient of the Oregon State Award for Discovery, the Media Award of the American College of Neuropsychopharmacology and was named a distinguished Alumnus of Baylor College of Medicine in 2012. Conn is a previous member of Council for the American Society for Cell Biology and the Endocrine Society and is a prior President of the Endocrine Society, during which time he founded the Hormone Foundation and worked with political leadership to heighten the public’s awareness of diabetes. Conn’s students and fellows have gone on to become leaders in industry and academia. He is an elected member of the Mexican Institute of Medicine and a fellow of the American Association for the Advancement of Science. He is the co-author of The Animal Research War (2008) and many articles for the public and academic community on the value of animal research and the dangers posed by animal extremism. His op/eds have appeared in The Washington Post, The LA Times, The Wall Street Journal, the Des Moines Register, and elsewhere. Conn consults with organizations that are influenced by animal extremism and with universities and companies facing challenges from these groups.
Texas Tech University Health Sciences Center, Lubbock, USA
University of Florida, Gainesville, U.S.A. Norris Professor of Life Sciences
J. Hillis Miller Health Science Center, University of Florida, Gainesville, U.S.A.
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