Neuroimaging, Part II

Neuroimaging, Part II

1st Edition - July 12, 2016

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  • Editors: Joseph Masdeu, R. Gilberto Gonzalez
  • Hardcover ISBN: 9780444534866
  • eBook ISBN: 9780702045387

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Neuroimaging, Part Two, a volume in The Handbook of Clinical Neurology series, illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This second volume covers imaging of the adult spine and peripheral nervous system, as well as pediatric neuroimaging. In addition, it provides an overview of the differential diagnosis of the most common imaging findings, such as ring enhancement on MRI, and a review of the indications for imaging in the most frequent neurological syndromes. The volume concludes with a review of neuroimaging in experimental animals and how it relates to neuropathology. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, with the entire field moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to the new horizon in the study of neurological disorders.

Key Features

  • Provides a relevant description of the technologies used in neuroimaging, such as computed tomography, magnetic resonance imaging, positron emission tomography, and several others
  • Discusses the application of these techniques to the study of brain and spinal cord disease
  • Explores the indications for the use of these techniques in various syndromes


Beginners and specialists in neurology, neurosurgery, psychology, biomedical engineering, radiology, and systems neuroscience

Table of Contents

  • Section III Spinal Diseases
    32. Functional anatomy of the spine
      Nikolai Bogduk
    33. Neuroimaging of spine tumors
      Laszlo Mechtler
    34. Vascular disease of the spine
      Timo Krings
    35. Infection
      Majda M. Thurnher
    36. Non-infectious inflammatory disorders
      Joshua P. Klein
    37. Imaging of trauma of the spine
      Vahe Michael Zohrabian and Adam Flanders
    38. Metabolic and hereditary myelopathies
      Peter Hedera
    39. Degenerative spine disease
      Paul M. Parizel

    Section IV Diseases of the Peripheral Nervous System
    40. Peripheral Nerves
      Neil Simon and Michel Kliot
    41. Muscle:MRI
      Bruce Damon
    42. Muscle: Ultrasound
      Sigrid Pillen, Nens van Alfen and Andrea Boon

    Section V Neurological Syndromes of the Adult: When and How to Image
    43 Sudden Neurological Deficit
      David S. Liebeskind and Conrad William Liang
    44.Pituitary imaging
      Anne Klibanski, Alexander T. Faje, Brooke Swearingen and Nicholas A. Tritos
    45. Visual Impairment
      Carl Ellenberger
    46. Vertigo and Hearing Loss
      David Newman-Toker
    47. Progressive Weakness or Numbness of Central or Peripheral Origin
      Joshua P. Klein
    48. Gait and balance disorders
      Joseph C. Masdeu
    49. Movement Disorders
      A Jon Stoessl and Martin McKeown
    50. Cognitive or Behavioral Impairment
      Alireza Atri
    51. Epilepsy
      Gregory Cascino, Graeme Jackson and William H. Theodore
    52. Myelopathy
      Patrick M. Capone
    53. Low Back Pain, Radiculopathy
      Robert L Ruff and Stephen M. Selkirk

    Section VI Differential Diagnosis of Imaging Findings
    54. Structural Imaging of the Brain: MRI, CT
      Joseph C. Masdeu
    55. Vascular Imaging: ultrasound
      Carlos A. Molina and David Rodriguez-Luna
    56. Diffusion tensor imaging and functional MRI
      Massimo Filippi Sr. and Federica Agosta

    Section VII Pediatric Neuroimaging
    57. Normal development
      Nadine Girard
    58. Congenital anomalies of the brain and spine
      Mauricio Castillo
    59. Tumors
      Andre Dietz Furtado, Ashok Panigrahy and Charles Fitz
    60. Vascular disease
      Catherine Amlie-Lefond
    61. Infections
      Jill V. Hunter
    62. Trauma
      Thierry A.G.M. Huisman
    63. Metabolic, endocrine and other genetic disorders
      Hisham Dahmoush, Elias Melhem and Arastoo Vossough
    64. Cerebrospinal fluid circulation disorders
      Harold L. Rekate and Ari Blitz
    65. Indications for the performance of neuroimaging in children
      Fenella Jane Kirkham

    Section VIII Interventional Neuroimaging
    66. Endovascular Treatment of Acute Ischemic Stroke
      Thabele M. Leslie-Mazwi, James D. Rabinov and Joshua A. Hirsch
    67. Endovascular treatment of Intracranial Aneurysms
      Orlando Diaz
    68. Endovascular treatment of vascular malformations
      Orlando Diaz

    Section IX Neuropathology and Experimental Models
    69. Postmortem imaging and neuropathologic correlations with imaging
      Jean C. Augustinack and Andre van der Kouwe

Product details

  • No. of pages: 720
  • Language: English
  • Copyright: © Elsevier 2016
  • Published: July 12, 2016
  • Imprint: Elsevier
  • Hardcover ISBN: 9780444534866
  • eBook ISBN: 9780702045387

About the Series Volume Editors

Joseph Masdeu

Joseph Masdeu

Joseph C. Masdeu, MD, PhD holds the Graham Family Distinguished Endowed Chair in Neurological Sciences at the Houston Methodist Institute of Academic Medicine and leads the Nantz National Alzheimer Center and Neuroimaging at the Houston Methodist Neurological and Research Institutes. He is Professor of Neurology at Weill Cornell Medical College.

Dr. Masdeu is interested in the application of neuroimaging tools, including new molecular neuroimaging markers, to the study of neurodegenerative brain disorders. By clarifying disease mechanisms and providing quantifiable markers of disease progression, this research will lead to the production of new medications and greatly facilitate the testing of new therapies in smaller and better characterized patient samples.

A native of Spain, where he became certified in Psychiatry after his MD degree at the University of Madrid, Dr. Masdeu is a US citizen who completed residency training in Chicago and was certified in Neurology by the American Board of Neurology and Psychiatry in 1976. He was a fellow in Neuropathology at the Brigham and Women’s Hospital of Harvard Medical School in 1976-77. In the 1980s, at the Albert Einstein College of Medicine, in New York, he directed the Alzheimer research component of a Program Project on Aging and Dementia. From 1991-2000 he was the Chairman of Neurology at the New York Medical College. He was Professor of Neurology and Director of Neurosciences at the University of Navarra Medical School, in Pamplona, Spain, from 2000-2008 and a Senior Staff Physician and Scientist at the Section of Integrative Neuroimaging of the Clinical Brain Disorders Branch of the Intramural Research Program of the National Institutes of Health (NIMH) from 2008-2014. He is the author of 142 peer-reviewed papers, 61 book chapters, and of seven books, including “Localization in Clinical Neurology,” now in its 6th edition. With a longstanding interest in neuroimaging, he is chairman of the Neuroimaging Research Group of the World Federation of Neurology. He has been a director of the American Academy of Neurology and president of the American Society of Neuroimaging. Since 2007 he is the Editor-in-Chief of the Journal of Neuroimaging.

Affiliations and Expertise

Director, Nantz National Alzheimer Center and Neuroimaging, Houston Methodist Hospital, Professor of Neurology, Weill Cornell Medical College, Houston, TX, USA

R. Gilberto Gonzalez

R. Gilberto Gonzalez
Dr. R. Gilberto González is Chief of Neuroradiology at the Massachusetts General Hospital and Professor of Radiology at the Harvard Medical School. He received his MD from Harvard Medical School and a PhD in biophysical chemistry from the University of California at Santa Cruz. He did post doctoral work in molecular biophysics at the Francis Bitter National Magnet Lab at MIT. His clinical training included an internship in medicine and a residency in radiology at the Brigham and Women's Hospital in Boston, and a neuroradiology fellowship at the MGH. He has published over 200 original, peer-reviewed scientific papers, over 100 chapters and reviews, and 3 books. He has published in the areas of ischemic stroke, brain tumors, cerebral hemorrhage, AIDS dementia and Alzheimer's disease, and has received research funding from the NIH, foundations and medical enterprises. He has given over 150 invited lectures at universities and at scientific meetings in the US, Europe, Latin America and Asia. He has received several honors including the Outstanding Researcher Award from the American Society of Neuroradiology, and has given the Taveras (Harvard), Newton (UCSF) and Wood (UNC) Lectures. He has reviewed grant applications as a member of NIH study sections and for several scientific organizations. Dr. González has been on the editorial board of the American Journal of Neuroradiology and Neurosurgery and is an ad hoc reviewer for many journals including the New England Journal of Medicine, The Lancet, Radiology and Stroke. He lives in Cambridge with his wife Michele, an atmospheric chemist, and their 2 daughters Susan and Ana.

Affiliations and Expertise

Professor of Radiology, Massachusetts General Hospital, Boston, MA, USA

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