Neurogenic Heart Lesions

Neurogenic Heart Lesions

1st Edition - January 1, 1980

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  • Editors: I. S. Zavodskaya, E. V. Moreva, N. A. Novikova
  • eBook ISBN: 9781483189536

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Description

Neurogenic Heart Lesions reviews the main publications concerned with the problem of neurogenic lesions of the heart. The book describes the methods for producing experimental neurogenic lesions, as well as the pharmacological analysis of the participation of the sympathetic nervous system and its transmitters in the development of neurogenic lesions of the myocardium. The text also discusses the changes in energy metabolism and in functional conditions of the myocardium caused by neurogenic lesions; and the pharmacoprophylaxis and pharmacotherapy of the biochemical changes produced by neurogenic lesions of the myocardium. Pharmacologists, pathologists, and other clinicians and physicians concerned with the new achievements in the field of cardiology will find the book invaluable.

Table of Contents


  • Foreword

    Introduction

    Chapter I: Methods for Producing Experimental Neurogenic Lesions

    Structural Myocardial Lesions Produced by Electrical Stimulation of the Hypothalamus

    Ultrastructural and Microscopic Changes Produced by Reflex Lesions of the Myocardium

    Pharmacological and Physiological Analysis of the Propagation Paths of the Impulses Producing Neurogenic Lesions of the Heart

    Chapter II: Pharmacological Analysis of the Participation of the Sympathetic Nervous System and its Transmitters in the Mechanism of Development of Neurogenic Lesions of the Myocardium

    Noradrenaline Levels in Myocardial Tissue during Excessive Stimulation

    Experiments with the Precursor of Noradrenaline — L-Dopa

    Experiments with the Central α-Adrenoblocker, IEM-611

    Experiments with Ethymisol

    Experiments with the Ganglioblocker, Benzohexamethonium

    Experiments with the β-Blocker, Propranolol

    Experiments with Toxic Doses of Catecholamines

    Chapter III: Changes in Energy Metabolism and in Functional Conditions of the Myocardium Caused by Neurogenic Lesions

    Glycogen Levels and the Process of Glycolysis during Excessive Stimulation of the Animals

    Oxidative Phosphorylation in the Mitochondria of the Heart Produced by its Neurogenic Lesion and the Injection of Toxic Doses of Noradrenaline

    High-Energy ATP and CP and Inorganic Phosphorus (IP) Levels in the Myocardium Produced by Excessive Stimulation

    The Activity of the First Stage of the Pentose-Phosphate Pathway — Glucose-6-Phosphate Dehydrogenase

    Electrocardiographic Data Obtained during Neurogenic Lesions of the Myocardium and the Injection of Large Doses of Noradrenaline

    Chapter IV: Pharmacoprophylaxis and Pharmacotherapy of the Biochemical Changes Produced by Neurogenic Lesions of the Myocardium

    Experiments with the Precursor of Noradrenaline, L-Dopa

    Experiments with Ethymisol

    Experiments with the Central α-Adrenoblocker, IEM-611

    Experiments with the Ganglioblocker, Benzohexamethonium

    Experiments with the β-Blocker, Propranolol

    Chapter V: The Analysis of Experimental and Clinical Data

    References

    Index

Product details

  • No. of pages: 150
  • Language: English
  • Copyright: © Pergamon 1980
  • Published: January 1, 1980
  • Imprint: Pergamon
  • eBook ISBN: 9781483189536

About the Editors

I. S. Zavodskaya

E. V. Moreva

N. A. Novikova

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