Neurogenic Heart Lesions - 1st Edition - ISBN: 9780080254821, 9781483189536

Neurogenic Heart Lesions

1st Edition

Editors: I. S. Zavodskaya E. V. Moreva N. A. Novikova
eBook ISBN: 9781483189536
Imprint: Pergamon
Published Date: 1st January 1980
Page Count: 150
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Description

Neurogenic Heart Lesions reviews the main publications concerned with the problem of neurogenic lesions of the heart. The book describes the methods for producing experimental neurogenic lesions, as well as the pharmacological analysis of the participation of the sympathetic nervous system and its transmitters in the development of neurogenic lesions of the myocardium. The text also discusses the changes in energy metabolism and in functional conditions of the myocardium caused by neurogenic lesions; and the pharmacoprophylaxis and pharmacotherapy of the biochemical changes produced by neurogenic lesions of the myocardium. Pharmacologists, pathologists, and other clinicians and physicians concerned with the new achievements in the field of cardiology will find the book invaluable.

Table of Contents


Foreword


Introduction


Chapter I: Methods for Producing Experimental Neurogenic Lesions


Structural Myocardial Lesions Produced by Electrical Stimulation of the Hypothalamus


Ultrastructural and Microscopic Changes Produced by Reflex Lesions of the Myocardium


Pharmacological and Physiological Analysis of the Propagation Paths of the Impulses Producing Neurogenic Lesions of the Heart


Chapter II: Pharmacological Analysis of the Participation of the Sympathetic Nervous System and its Transmitters in the Mechanism of Development of Neurogenic Lesions of the Myocardium


Noradrenaline Levels in Myocardial Tissue during Excessive Stimulation


Experiments with the Precursor of Noradrenaline — L-Dopa


Experiments with the Central α-Adrenoblocker, IEM-611


Experiments with Ethymisol


Experiments with the Ganglioblocker, Benzohexamethonium


Experiments with the β-Blocker, Propranolol


Experiments with Toxic Doses of Catecholamines


Chapter III: Changes in Energy Metabolism and in Functional Conditions of the Myocardium Caused by Neurogenic Lesions


Glycogen Levels and the Process of Glycolysis during Excessive Stimulation of the Animals


Oxidative Phosphorylation in the Mitochondria of the Heart Produced by its Neurogenic Lesion and the Injection of Toxic Doses of Noradrenaline


High-Energy ATP and CP and Inorganic Phosphorus (IP) Levels in the Myocardium Produced by Excessive Stimulation


The Activity of the First Stage of the Pentose-Phosphate Pathway — Glucose-6-Phosphate Dehydrogenase


Electrocardiographic Data Obtained during Neurogenic Lesions of the Myocardium and the Injection of Large Doses of Noradrenaline


Chapter IV: Pharmacoprophylaxis and Pharmacotherapy of the Biochemical Changes Produced by Neurogenic Lesions of the Myocard

Details

No. of pages:
150
Language:
English
Copyright:
© Pergamon 1980
Published:
Imprint:
Pergamon
eBook ISBN:
9781483189536

About the Editor

I. S. Zavodskaya

E. V. Moreva

N. A. Novikova

Ratings and Reviews