Volume II

1st Edition - January 1, 1967

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  • Editors: Luciano Martini, William F. Ganong
  • eBook ISBN: 9781483275055

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Neuroendocrinology, Volume II, is the second in a two-volume treatise designed to provide a survey of all aspects of the rapidly expanding science of neuroendocrinology. Only in recent years have the relations between the nervous system and the endocrine system come under intensive scrutiny, but their interactions have already been shown to be multiple and diverse. This diversity is reflected in the range of subjects covered. There are chapters on neural control of endocrine function; the effects of hormones on the brain; brain-endocrine interrelations during various phases of development; and the comparative aspects of neuroendocrine integration. The relation of brain chemistry to endocrine function, the effect of drugs on neuroendocrine mechanisms, and the new discipline of clinical neuroendocrinology have also been considered. Not only neurophysiologists and endocrinologists, but pharmacologists, zoologists, biochemists, psychologists, and those in clinical medicine will find the treatise of interest. Parts of neuroendocrinology have been discussed in other works, but this is the first treatise in which an attempt has been made to cover all ramifications of neuroendocrinology. This book can be used both as a text for advanced students and as a reference source.

Table of Contents

  • List of Contributors


    Contents of Volume I

    Erratum for Volume I

    Chapter 17. Role in Reproductive Physiology of Afferent Impulses from the Genitalia and Other Regions

    I. Introduction

    II. Innervation of the Reproductive Tract

    III. The Role of Peripheral Nerves in Reproductive Processes in the Male

    IV. The Role of Peripheral Nerves in Reproductive Processes in the Female

    V. Modification of Gonadal Function by Manipulation of the Genital Tract

    VI. Exteroceptive Stimuli Influencing Reproductive Processes

    VII. Summary and Conclusions


    Chapter 18. Effects of Light and Visual Stimuli on Endocrine Function

    I. Introduction

    II. Physical and Temporal Characteristics of Natural Light, and Their Endocrine Significance

    III. The Responses of Animals to Light

    V. Methods Used to Study the Endocrine Effects of Light, and Common Problems in the Interpretation of Data

    V. Mechanisms by Which Light Influences Selected Neuroendocrine Functions

    VI. Summary


    Chapter 19. Modifications in Reproductive Function after Exposure to Hormones during the Prenatal and Early Postnatal Period

    I. General Introduction

    II. The Effect of Pre- and Postnatal Hormone Treatment on Subsequent Reproduction

    III. The Persistent Estrus Syndrome, Its Cause, and Its Contribution to the Understanding of the Normal Estrous Cycle

    IV. Effects of Prepubertal Androgen Treatment on Pituitary Gonadotropin

    V. Comparative Effects of Prepubertal Treatment with Hormones Other Than Androgen of Subsequent Fertility

    VI. Effects of Prepubertal Steroid Treatment on Mating Behavior

    VII. Influence of Exogenous Hormone Administration in Adult Female Rats Pretreated with Sex Steroids before Puberty

    VIII. Influence of Prepubertal Hormone Treatment on Subsequent Ovarian Steroidogenesis

    IX. Influence of Prepubertal Administration of Sex Steroids on Reproductive Physiology of the Male

    X. Other Effects of Prepubertal Steroid Treatment

    XI. General Comments and Conclusions


    Chapter 20. Control of the Onset of Puberty

    I. Introduction

    II. Prepubertal Development of the Gonads

    III. The Pituitary and Puberty

    IV. The Brain and Puberty

    V. Control of Puberty



    Chapter 21. Sexual Behavior: General Aspects

    I. Introduction

    II. Gonadal Hormones and Activation of Sexual Behavior in Adult Mammals

    III. Gonadal Hormones and Organization of Sexual Behavior

    IV. Genetic and Hormonal Interaction

    V. Summary


    Chapter 22. Sexual Behavior: Hormonal Control

    I. Introduction

    II. The Nervous System: Role in Sexual Behavior

    III. Sexual Behavior in Nonmammalian Vertebrates

    IV. Concluding Remarks


    Chapter 23. Melanocyte-Stimulating Hormone and the Intermediate Lobe of the Pituitary: Chemistry, Effects, and Mode of Action

    I. Introduction

    II. Chemistry of Melanocyte-Stimulating Hormone

    III. Effects of Melanocyte-Stimulating Hormone

    IV. Mode of Action of Melanocyte-Stimulating Hormone

    V. Concluding Remarks


    Chapter 24. Relation of the Pars Intermedia to the Hypothalamus

    I. Introduction

    II. Morphological Considerations

    III. Developmental Interactions

    IV. Neural Inhibition of the Intermedia

    V. Nature of Neural Control

    VI. Summary


    Chapter 25. Adrenal Medullary Secretion and Its Neural Control

    I. Morphological Considerations

    II. Hormones of the Adrenal Medulla

    III. Action of Medullary Hormones

    IV. Adrenal Medullary Secretion

    V. Mechanism of Release

    VI. Chromaffin Cell Tumors

    VII. Summary


    Chapter 26. Influence of Hormones on Brain Activity

    I. Introduction

    II. Methods for Measuring Central Nervous System Activity

    III. Adrenal Gland

    VI. Gonads

    V. Thyroid Gland

    VI. Parathyroid Gland

    VII. Pancreas

    VIII. Growth Hormone (Somatotropin)

    IX. Summary


    Chapter 27. Effects of Drugs on Neuroendocrine Processes

    I. Introduction

    II. Hormone Congeners

    III. Drugs Acting Directly on Endocrine Organs

    IV. Drugs Inhibiting the Actions of Hormones on Their Target Organs

    V. Drugs Altering Hormone Secretion by Acting on the Nervous System

    VI. Conclusions


    Chapter 28. Neuroendocrine Mechanisms in Invertebrates

    I. Introduction

    II. The Components of Invertebrate Neuroendocrine Control

    III. Brief Survey of Neuroendocrine Mechanisms in the Invertebrates

    IV. General Comments and Conclusions


    Chapter 29. Neuroendocrine Mechanisms in Lower Vertebrates

    I. Introduction

    II. Comparative Anatomy of the Hypophyseal Region

    III. Functional Hypothalamic-Adenohypophyseal Relationships

    IV. Extrahypophyseal Functions of the Neurohypophyseal Hormones in Lower Vertebrates

    V. Discussion and Conclusions

    VI. Summary


    Chapter 30. Neuroendocrine Mechanisms in Birds

    I. Introduction

    II. General Features of the Avian Hypothalamo-Hypophyseal System

    III. The Morphology of the Avian Hypothalamo-Hypophyseal System

    IV. Functional Aspects

    V. Neurohormones and Releasing Mechanisms

    VI. Afferent Information for Hypothalamic Neuroendocrine Mechanisms

    VII. Summary


    Chapter 31. Brain Neurohumors and Endocrine Function

    I. Introduction

    II. Distribution of Neurohumors in the Brain

    III. Metabolism of Neurohumors

    IV. Neurohumors as Mediators at Synapses in the Brain

    V. Melatonin

    VI. Relation of Neurohumors to Endocrine Function

    VII. Conclusions


    Chapter 32. Possible Functions of the Pineal Gland

    I. Introduction

    II. Pineal Contents and Metabolic Activity

    III. Melatonin

    IV. Relation to the Brain

    V. Effects of Light on the Pineal Gland

    VI. Relation to the Gonads

    VII. Relation to the Adrenal Glands

    VIII. Relation to the Thyroid Gland

    IX. Relation to the Pituitary Gland

    X. Comment


    Chapter 33. Abnormalities of Neuroendocrine Functions in Man

    I. Limitations in the Study of Neuroendocrine Functions in Man

    II. Gross Deficits of Endocrine Function in Cerebral Disease

    III. Asymptomatic Disturbances in Endocrine Control Mechanisms

    IV. Effect of Drugs on Neuroendocrine Function in Man

    V. Possible Relationship between the Central Nervous System and Certain Clinical States

    VI. Role of the Central Nervous System in the Regulation of Salt and Water Metabolism in Man

    VII. Summary


    Author Index

    Subject Index

Product details

  • No. of pages: 798
  • Language: English
  • Copyright: © Academic Press 1967
  • Published: January 1, 1967
  • Imprint: Academic Press
  • eBook ISBN: 9781483275055

About the Editors

Luciano Martini

Affiliations and Expertise

Department of Endocrinology, University of Milano, Milano, Italy

William F. Ganong

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