Pathological Situations and Diseases

1st Edition - June 29, 2010

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  • Editors: Luciano Martini, George Chrousos, Fernand Labrie, Karel Pacek, Donald Pfaff
  • eBook ISBN: 9780444537393
  • Hardcover ISBN: 9780444536167

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Neuroendocrinology is a discipline which originated about 50 years ago as a branch of Endocrinology and that is now strictly linked to neuroscience. Volumes 181 and 182 of Progress in Brain Research provide a rapid view of the major points presently discussed at biological and clinical levels. The chapters have been written by top scientists who are directly involved in basic or clinical research and who use the most sophisticated biotechnological techniques. The volumes cover of the role of genetics in many endocrine-related events, like neuroendocrinological diseases and endocrine depenedent cancers (prostate, breast, etc,). Interesting information is also provided on possibile treatments of neurodegenerative brain diseases (e.g., Alzheimer and similar syndromes).

Key Features

• The best researchers in the field provide their conclusions in the context of the latest experimental results

• Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered

• Of great value for researchers and experts, but also for students as a background reference


Neurologists, Neuroscientists, Neuropsychologists

Table of Contents

  • 1. Glucocorticoid-induced apoptosis of healthy and malignant lymphocytes
    L.K. Smith and J.A. Cidlowski (North Carolina, USA)

    2. Impact of the hypothalamic–pituitary–adrenal/gonadal axes on trajectory of age-related cognitive decline
    C.D. Conrad and H.A. Bimonte-Nelson (Arizona, USA)

    3. Menopause and mitochondria: windows into estrogen effects on Alzheimer’s disease risk and therapy
    V.W. Henderson and R. Diaz Brinton (California, USA)

    4. DHEA, important source of sex steroids in men and even more in women
    F. Labrie (Quebec, Canada)

    5. Neuroendocrinology of post-traumatic stress disorder
    P. Pervanidou and G.P. Chrousos (Athens, Greece)

    6. Assisted reproduction and its neuroendocrine impact on the offspring
    C. Kanaka-Gantenbein, S. Sakka and G.P. Chrousos (Athens, Greece)

    7. Sex hormone and neuroendocrine aspects of the metabolic syndrome
    H. Nawata, T. Watanabe, T. Yanase, M. Nomura, K. Ashida, L. Min and W. Fan (Fukuoka, Japan)

    8. Ghrelin’s role as a major regulator of appetite and its other functions in neuroendocrinology
    C.T. Lim, B. Kola, M. Korbonits and A.B. Grossman (London, UK)

    9. Pathogenesis of pituitary tumors
    R. Yu and S. Melmed (California, USA)

    10. Molecular genetics of the AIP gene in familial pituitary tumorigenesis
    A. Tahir, H.S. Chahal and M. Korbonits (London, UK)

    11. Somatostatin and somatostatin receptors: from basic concepts to clinical applications
    M.C. De Martino, L.J. Hofland and S.W.J. Lamberts (Rotterdam, The Netherlands)

    12. Somatostatin analogues: treatment of pituitary and neuroendocrine tumors
    A. Colao, A. Faggiano and R. Pivonello (Naples, Italy)

    13. The MENX syndrome and p27: relationships with multiple endocrine neoplasia
    S. Molatore and N.S. Pellegata (Neuherberg, Germany)

    14. Hormonal therapy of prostate cancer
    F. Labrie (Quebec, Canada)

    15. Pheochromocytoma and paraganglioma
    V. Kantorovich and K. Pacak (Arkausas and Maryland, USA)

Product details

  • No. of pages: 400
  • Language: English
  • Copyright: © Elsevier Science 2010
  • Published: June 29, 2010
  • Imprint: Elsevier Science
  • eBook ISBN: 9780444537393
  • Hardcover ISBN: 9780444536167

About the Serial Volume Editors

Luciano Martini

Affiliations and Expertise

Department of Endocrinology, University of Milano, Milano, Italy

George Chrousos

Affiliations and Expertise

First Department of Pediatrics, Athens University Medical School, Athens, Greece

Fernand Labrie

Affiliations and Expertise

Molecular Endocrinology, Laval University Hospital, Quebec City, Canada

Karel Pacek

Affiliations and Expertise

Section of Medical Neuroendocrinology, NICHD-NIH, Bethesda, MD, USA

Donald Pfaff

Donald W. Pfaff heads the Laboratory of Neurobiology and Behavior at The Rockefeller University. He received his scientific training at Harvard College and MIT. He is a Member of the U.S. National Academy of Sciences and a Fellow of the American Academy of Arts and Sciences. Pfaff's laboratory focuses on steroid hormones and brain function, genes influencing neuronal functions, and generalized CNS arousal. He is the author or coauthor of over 10 books and more than 900 research publications.

Affiliations and Expertise

Laboratory of Neurobiology and Behavior, Rockefeller University, New York, USA

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