Neuroendocrine Perspectives

1st Edition

Volume 3

Editors: Eugenio E. Müller Robert M. MacLeod
Hardcover ISBN: 9780444903778
eBook ISBN: 9781483278131
Imprint: Elsevier
Published Date: 1st January 1984
Page Count: 398
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Neuroendocrine Perspectives, Volume 3 provides information on amine and peptide biochemistry. This book discusses the availability of specific biochemical and histochemical techniques that have greatly advanced knowledge of central nervous system neurotransmitter and neuropeptide systems. Organized into nine chapters, this volume begins with an overview of the structure of corticotropin releasing hormone. This text then examines the possible role of the cerebrospinal fluid in the regulation of pituitary function. Other chapters consider the importance of cerebrospinal fluid as a route for the hypothalamic regulation of pituitary function. This book discusses as well the available information concerning the neuroendocrine mechanisms involved in the onset of female puberty in primate and subprimate species. The final chapter deals with pineal indole metabolism and its controlling mechanisms as well as information on the interactions of the pineal hormones with neuroendocrine-reproductive axis. This book is a valuable resource for pharmacologists, research workers, and students.

Table of Contents

Contents Introduction Contributors Chapter 1 Topography of Chemically Identified Neurons in the Central Nervous System: Progress in 1981-1983 Introduction Amino Acids

1. GABA 2. Glycine 3. Glutamate 4. Aspartate 5. Taurine Acetylcholine Biogenic Amines 1. Dopamine 2. Norepinephrine 3. Epinephrine 4. Histamine 5. Serotonin 6. Minor Biogenic Amines Neuropeptides 1. Hypothalamic Neuropeptides 2. Brain-Borne Pituitary Peptides 3. Opioid Peptides 4. Brain-Borne Gastro-Intestinal Peptides 5. Other Neuropeptides Conclusions

Chapter 2 Hypothalamic Organization of Corticotropin Releasing Factor (CRF) Producing Structures Introduction The Hypophysiotropic Neurons Location of Hypothalamic CRF-Producing Structures Early Studies Reevaluation The Role of The Hypothalamic Paraventricular Nucleus Is The Neural Lobe Involved in the Control of ACTH Secretion? What Is CRF? The 41-Residue CRF (CRF-41)

1. Effects in Vitroand in Vivo 2. Functional Studies 3. Hypothalamic Distribution of Ocrf-41i 4. Conclusions The Neurohypophyseal Peptides Vasopressinand Oxytocin 1. Effects in Vitroand in Vivo 2. Functional Studies 3. Hypothalamic Distribution of Vasopressinand Oxytocin 4. Conclusions Angiotensin II 1. Effects in Vitroand in Vivo 2. Functional Studies 3. Hypothalamic Distribution of Angiotensin II 4. Conclusions Epinephrineand Norepinephrine 1. Effects in Vitroand in Vivo 2. Functional Evidence 3. Hypothalamic Distribution of Epinephrineand Norepinephrine 4. Conclusions Other Substances With CRF Activity Perspectives of CRF

Chapter 3 Neuropeptides in the Cerebrospinal Fluid Introduction Hypophysiotropic Function Mechanisms By Which Neural Peptides Might Reach The CSF

1. Trans-Median Eminence Transport 2. Circumventricular Organs 3. Diffusion From Nerve Cells 4. T


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© Elsevier 1984
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About the Editor

Eugenio E. Müller

Robert M. MacLeod