Netter's Infectious Diseases

2nd Edition - March 19, 2021
Editors: Elaine C. Jong, Dennis L. Stevens
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 1 1 5 9 - 3
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 7 5 9 6 - 0

Widely used by students, residents, generalists, and specialists, Netter’s Infectious Diseases, 2nd Edition delivers must-know information on infectious diseases in a highly il… Read more

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Widely used by students, residents, generalists, and specialists, Netter’s Infectious Diseases, 2nd Edition delivers must-know information on infectious diseases in a highly illustrated, easily accessible format. Concise visual overviews of essential topics provide a convenient, trustworthy way to review the basics of a given infectious disease or issue or to share with patients or staff. Drs. Elaine Jong and Dennis Stevens cover the wide spectrum of illness and disease in this complex field using memorable illustrations by world-renowned artist Frank H. Netter and others, offering a time-saving, authoritative look at infectious disease risk factors, clinical presentations, pathophysiology, and more.

Instructions for online access
Cover image
Title page
Table of Contents
Copyright
About the Artists
About the Editors
Acknowledgments
Preface
Contributors
Online Contents
SECTION I. Vaccine-Preventable Diseases in Children and Adolescents
1. Introduction to Vaccine-Preventable Diseases in Children and Adolescents
Geographic Distribution and Epidemiological Trends
General Principles
Types of Immunizations
Vaccine Recipients
Adverse Events and Vaccine Information
2. Diphtheria and Tetanus
Diphtheria
Tetanus
Prevention and Control of Diphtheria and Tetanus
3. Bordetella pertussis and Pertussis (Whooping Cough)
Geographic Distribution and Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management
Prognosis
Prevention and Control: Vaccines
4. Haemophilus influenzae Type b
Geographic Distribution and Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management
Prognosis
Prevention and Control
5. Pneumococcal Disease: Infections Caused by Streptococcus pneumoniae
Geographic Distribution and Burden of Disease
Microbiology and Pathogenesis
Risk Factors
Clinical Presentation
Diagnostic Approach
Treatment
Prognosis
Prevention
6. Infections Caused by Neisseria meningitidis
Geographic Distribution and Burden Of Disease
Pathogenesis
Clinical Presentation
Diagnostic Approach
Treatment
Prognosis
Prevention and Control
7. Poliomyelitis (Polio) and Polioviruses
Epidemiology, Geographic Distribution, and Disease Burden
Risk Factors
Clinical Features
Differential Diagnosis
Clinical Management and Drug Treatment
Prognosis
Prevention and Control
8. Influenza
Geographic Distribution and Magnitude of Disease Burden
Risk Factors for Endemic Disease
Clinical Features
Complications
Diagnostic Approach
Clinical Management
Prognosis
Prevention and Control
9. Rotavirus Infection
Geographic Distribution and Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Treatment
Prevention and Control
Future Directions
10. Measles
Global Epidemiology and Contagiousness
Clinical Features
Atypical Presentations
Complications
Diagnosis
Treatment
Reduction of Global Disease Burden
11. Mumps
Geographic Distribution
Risk Factors
Clinical Features
Diagnosis
Clinical Management
Prevention and Control
Notes
12. Rubella
Geographic Distribution
Pathogenesis
Clinical Features
Diagnosis
Treatment
Prevention and Control
Notes
13. Varicella-Zoster Virus Infections
Geographic Distribution and Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management
Prognosis
Prevention and Control
14. Hepatitis A Infection and Prevention
Etiology
Geographic Distribution and Magnitude of Disease Burden
Risk Factors for Infection
Clinical Features
Complications
Diagnostic Approach
Clinical Management
Prognosis
Prevention and Control
15. Hepatitis B Infection
Etiology
Geographic Distribution and Magnitude of Disease Burden
Risk Factors for Infection
Clinical Features
Diagnostic Approach
Differential Diagnosis
Clinical Management
Prognosis
Prevention and Control
16. Human Papillomavirus Infections and Prevention
Etiology
Geographic Distribution and Magnitude of Disease Burden
Risk Factors for Infection
Clinical Presentation
Diagnostic Approach
Treatment
Prognosis
Prevention and Control
SECTION II. Skin and Soft-Tissue Infections
17. Introduction to Skin and Soft-Tissue Infections
Epidemiology
Pathogenesis
Prevention
18. Impetigo
Geographic Distribution
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management
Prognosis
Prevention and Control
19. Erysipelas and Cellulitis
Disease Burden, Epidemiology, and Microbiology
Pathogenesis and Risk Factors
Clinical Features
Diagnosis
Differential Diagnosis
Management and Antibiotic Treatment
20. Folliculitis, Furuncles, and Carbuncles
Disease Burden
Pathogenesis of Cutaneous Infection and the Genetics of Mrsa Strains
Risk Factors
Clinical Features of Folliculitis, Furuncles, and Carbuncles
Diagnostic Approach
Treatment
Prevention and Control
Summary
21. Life-Threatening Skin and Soft-Tissue Infections
Disease Burden
Staphylococcal Toxic Shock Syndrome
Streptococcal Toxic Shock Syndrome
Scarlet Fever
Staphylococcal Scalded Skin Syndrome
Necrotizing Fasciitis
Clostridial Myonecrosis (Gas Gangrene)
Future Directions
22. Superficial Dermatophyte Infections of the Skin
Disease Burden
Pathogenesis and Risk Factors
Clinical Features
Diagnostic Methods
23. Herpes Simplex Virus Infection
Geographic Distribution and Magnitude of Disease Burden
Risk Factors for Infection and Disease
Clinical Features
Diagnostic Approach
Differential Diagnosis
Treatment
Prognosis
Prevention and Control
24. Nontuberculous Mycobacterial Skin and Soft-Tissue Infections
Epidemiology
Pathogenesis
Clinical Presentation
Diagnostic Approach
Treatment
SECTION III. Respiratory Tract Infections
25. Introduction to Respiratory Tract Infections
26. Community-Acquired Pneumonia, Bacterial
Introduction
Disease Burden
Pathogenesis and Risk Factors
Microbiology
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prognosis
Prevention
27. Hospital-Acquired Pneumonia
Epidemiology and Impact
Pathophysiology
Microbiology
Clinical Presentation
Diagnostic Approach
Treatment
Prognosis
Prevention
Future Directions
28. Atypical Pneumonia
Burden of Disease
Pathogenesis
Clinical Features
Diagnostic Approach
Antimicrobial Therapy
Prevention
29. Aspiration Pneumonia
Burden of Disease
Microbiology and Pathogenesis
Risk Factors
Clinical Manifestations
Diagnosis
Treatment
Prevention
30. Viral Respiratory Infections
Influenza Virus
Avian Influenza and Pandemic Influenza
Respiratory Syncytial Virus
Other Respiratory Viruses
31. Sinus Infections
Anatomic Considerations
Epidemiology and Risk Factors
Microbiology
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Complications
Prevention and Control
32. Acute Otitis Media
Magnitude of the Problem, Risk Factors, Pathogenesis, and Etiology
Clinical Features and Diagnosis
Clinical Management and Drug Treatment
Prevention
33. Pharyngitis
Epidemiology
Diagnosis
Treatment
34. Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Management
Prognosis
Prevention
SECTION IV. Systemic Infections
35. Introduction to Systemic Infections
36. Endocarditis
Pathogenesis
Risk Factors
Clinical Presentation
Diagnostic Approach
Treatment
Prosthetic Valve Endocarditis
Prevention
37. Meningitis
Anatomic and Physiologic Considerations
Epidemiology
Pathogenesis and Pathophysiology
Clinical Features
Diagnosis
Management of Patients with Suspected Meningitis
Prognosis
Conclusions
38. Osteomyelitis
Hematogenous Osteomyelitis
Chronic Osteomyelitis
Nonhematogenous Osteomyelitis
Pseudomonas Osteochondritis
Patellar Osteochondritis
Contiguous Osteochondritis
Pelvic Osteomyelitis
Vertebral Osteomyelitis
Chronic Recurrent Multifocal Osteomyelitis
39. Urinary Tract Infections
Risk Factors
Clinical Features
Diagnostic Approach
Management and Therapy
Summary
40. Systemic Fungal Infections
Epidemiology
Clinical Features
Diagnostic Approach
Treatment
Prognosis
SECTION V. Surgical Infections
41. Surgical Infections: Introduction and Overview
42. Acute Appendicitis
Risk Factors and Pathophysiology
Clinical Presentation
Diagnostic Approach
Treatment
Prognosis
43. Acute Ascending Cholangitis and Suppurative Toxic Cholangitis
Geographic Distribution And Magnitude Of Disease Burden
Pathogenesis
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management and Treatment
Prognosis
Prevention
44. Acute Diverticulitis
Risk Factors and Pathophysiology
Clinical Presentation
Diagnostic Approach
Treatment
Prognosis
Prevention and Control
45. Hydatid Cyst Disease (Echinococcosis)
Geographic Distribution and Magnitude of Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prognosis
Prevention and Control
46. Intraabdominal Abscess
Etiology and Geographic Distribution
Risk Factors
Clinical Presentation
Diagnostic Evaluation
Clinical Management and Drug Treatment
Prognosis
Prevention and Control
47. Liver Abscess: Pyogenic and Amebic Hepatic Abscess
Geographic Distribution and Magnitude of Disease Burden
Pathogenesis
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management and Treatment
Prognosis
48. Necrotizing Soft-Tissue Infections
Risk Factors
Clinical Presentation
Diagnostic Approach
Treatment
Prognosis
Control and Prevention
49. Anorectal Abscess and Fistula in Ano
Introduction
Etiology and Clinical Features
History and Physical Examination
Abscess Location and Management
Fistula in Ano Etiology and Evaluation
Fistula in Ano Management
Anal Fistula Associated with Crohn’s Disease
Summary and Future Efforts
50. Peritonitis
Geographic Distribution and Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prognosis
51. Pyomyositis (Pyomyositis Tropicans)
Introduction and Epidemiology
Microbiology
Clinical Features
Diagnosis
Treatment
52. Surgical Site Infections
Definitions
Risk Factors
Diagnostic Approach
Treatment
SECTION VI. Sexually Transmitted Infections
53. Introduction to Sexually Transmitted Infections
54. Trichomonas vaginalis
Epidemiology
Etiology/Pathophysiology
Diagnostic Approach
Treatment
Prevention and Control
Future Directions
55. Herpes Simplex Virus Genital Infection
Epidemiology
Clinical Features
Neonatal Herpes
Genital Herpes and Human Immunodeficiency Virus
Pathophysiology
Laboratory Testing
Management
Prevention and Control
Summary
56. Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome
Origins and Geographic Distribution of Human Immunodeficiency Virus Infection
Modes of Transmission
Prevention of Infection
Clinical Features, Pathogenesis, and Progression of Human Immunodeficiency Virus-1 Infection
Diagnostic Approach
Clinical Management and Treatment
Prognosis and Future Directions
57. Human Papillomavirus
Background
Geographic Distribution and Magnitude of Infection and Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prognosis
Prevention and Control
Disclaimer
58. Infections Caused by Chlamydia trachomatis, Including Lymphogranuloma Venereum
Geographic Distribution and Magnitude of Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prognosis
Prevention and Control
59. Infections With Neisseria gonorrhoeae
Epidemiology
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prognosis
Prevention and Control
60. Syphilis (Treponema pallidum)
Etiology and Pathogenesis
Epidemiology
Clinical Features
Diagnostic Approach
Treatment
Prevention and Control
Future Directions
61. Bacterial Vaginosis, Related Syndromes, and Less Common Sexually Transmitted Diseases
Bacterial Vaginosis
Chancroid
Granuloma Inguinale (Donovanosis)
SECTION VII. Infections Associated With International Travel and Outdoor Activities
62. Introduction to Infections Associated With International Travel and Outdoor Activities
Illness in Returned Travelers
“Where are You Going…Where Have You Been?”
63. Malaria
Epidemiology
Life Cycle and Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prevention and Control
Prevention of Relapse
64. Yellow Fever
Etiology and Transmission
Geographic Distribution
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management
Prognosis
Prevention and Control
65. Travelers’ Diarrhea
Agents of Infection
Diagnosis
Treatment
Prevention
66. Cholera
Etiology and Pathophysiology
Epidemiology
Clinical Presentation
Diagnostic Approach
Treatment
Prevention and Vaccination
67. Enteric Fever: Typhoid and Paratyphoid Fever
Geographic Distribution
Transmission and Pathogenesis
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Typhoid Carrier
Prevention
68. Hepatitis A, B, C, D, and E: Focus on Adult Infections
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E
69. Rabies
Geographic Distribution
Etiology
Pathophysiology
Clinical Features
Differential Diagnosis
Diagnostic Approach
Treatment
Prevention
70. Arboviruses of Medical Importance
Geographic Distribution and Risk Factors
Clinical Presentation
Diagnosis
Treatment
Prevention
Future Directions
71. West Nile Virus Disease
Etiology and Transmission
Geographic Distribution
Public Health Importance
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management
Prognosis
Prevention and Control
72. Tick-Borne Encephalitis
The Pathogen
Vector and Transmission
Epidemiology
Clinical Features
Diagnostic Approach
Treatment
Prognosis
Prevention
73. Lyme Disease
Geographic Distribution
Tick Life Cycle
Risk Factors
Clinical Presentation
Diagnostic Approach
Differential Diagnosis
Treatment
Postexposure Prophylaxis
Prevention
Other Tick-Borne Diseases
74. Leptospirosis
Transmission and Risk of Infection
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prognosis
Prevention and Control
75. Primary Amebic Meningoencephalitis
Etiology/Pathogenesis
Clinical Presentation
Diagnostic Approach
Treatment
Prevention and Control
Future Directions
SECTION VIII. Parasitic Diseases
76. Introduction to Parasitic Diseases
77. Amebiasis
Introduction
Etiology/Pathophysiology
Epidemiology
Clinical Presentation
Diagnostic Approach
Treatment
Prevention
78. Giardia, Cryptosporidium, Cyclospora, and Other Intestinal Protozoa
Etiologic Agents
Epidemiology and Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Other Intestinal Protozoa
Prevention and Control
79. Soil-Transmitted Helminths and Other Intestinal Roundworms
Geographic Distribution
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prevention and Control
80. Intestinal Cestodes (Tapeworms)
Clinical Presentation and Manifestations
Diagnosis and Management
Prevention
81. Cysticercosis
Etiology/Pathophysiology
Clinical Presentation
Diagnostic Approach
Treatment
Future Directions
82. Food-Borne Trematodes: Liver, Lung, and Intestinal Flukes
Geographic Distribution
Life Cycle
Clinical Presentation
Diagnostic Approach
Treatment
Prevention and Control
83. Schistosomiasis
Geographic Distribution
Life Cycle
Clinical Presentation
Diagnostic Approach
Treatment
Prevention and Control
84. Filarial Diseases
Geographic Distribution and Magnitude of Disease Burden
Risk Factors
Clinical Presentation and Pathogenesis
Diagnostic Approach
Treatment
Prognosis
Prevention and Control
85. Echinococcosis: Cystic and Alveolar Disease
Infection With Echinococcus Granulosus (Cystic Echinococcosis, or Hydatid Cyst)
Infection With Echinococcus Multilocularis (Alveolar Echinococcosis)
86. Trichinellosis
Geographic Distribution
Life Cycle
Clinical Features
Diagnostic Approach
Treatment
Prevention
87. Chagas Disease
Geographic Distribution and Epidemiology
Clinical and Laboratory Manifestations
Laboratory Diagnosis of Chagas Disease
Clinical Management
Prevention and Control
Summary
SECTION IX. Emerging Infectious Diseases and Pandemics
88. Introduction to Emerging Infectious Diseases and Pandemics
89. Multidrug-Resistant Tuberculosis
Epidemiology
Background
Clinical Features and Diagnostic Approach
Differential Diagnosis
Management and Therapy
Special Populations
Public Health Considerations
Future Directions
90. Anthrax
Disease Burden and Risk Factors
Etiology/Pathophysiology
Clinical Presentation
Differential Diagnosis
Diagnostic Approach
Treatment
Prevention
91. Tularemia
Geographic Distribution and Magnitude of Disease Burden
Risk Factors
Clinical Features
Diagnostic Approach
Clinical Management and Drug Treatment
Prognosis
Prevention and Control
92. Zika Virus Disease and Congenital Zika Virus Infection
Etiology/Pathophysiology
Transmission
Epidemiology
Clinical Presentation
Diagnostic Approach
Clinical Management
Prevention and Control
Future Directions
93. Neuroangiostrongyliasis (Rat Lungworm Disease)
Etiology
Epidemiology
Clinical Presentation
Diagnostic Approach
Treatment
Prevention
94. Ebola and Other Emerging Viral Hemorrhagic Fevers
Ebola Virus Disease
Other Emerging Viral Hemorrhagic Fevers
95. Severe Acute Respiratory Syndrome and Coronavirus Disease 2019
Severe Acute Respiratory Syndrome
Coronavirus Disease 2019
96. Middle East Respiratory Syndrome Coronavirus
Geographic Distribution and Magnitude of Disease Burden
Risk Factors
Clinical Features
laboratory/radiographic findings
Diagnostic Approach
Clinical Management and Drug Treatment
Prognosis
Prevention and Control
Summary
97. Influenza Virus: A Public Health Concern
Geographic Distribution and Seasonality
Emergence of Pandemic Influenza Virus Strains
Past Influenza Pandemics
Influenza Viruses in Recent Circulation
Influenza Virus as a Bioweapon
Prevention and Control of Influenza
Influenza Preparedness Plan
Index

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Elaine C. Jong

Dennis L. Stevens