Key Features

Summary tables and terminology sections at the end of each chapter, plus an appendix with all major congenital defects and their embryonic basis, make it easy to review course material and prepare for the USMLE.

Table of Contents

Chapter 1

An Overview of Developmental Events, Processes, and Abnormalities 1
The First and Second Weeks 2
The Embryonic Period
The Early Embryonic Period 3
The Late Embryonic Period 4
The Fetal Period 5
Histological Concepts
Samples of Epithelia and Connective Tissue 6
Skin and Embryonic Connective Tissue 7
Induction 8
Apoptosis 9
Segmentation and Early Pattern Formation
Genetic Determination of Embryonic Axes and Segments 10
Segmentation and Segment Fates 11
Cell Adhesion and Cell Migration 12
Cell Differentiation and Cell Fates 13
Growth Factors 14
Classification of Abnormal Processes 15
Classification of Multiple Anomalies 16
Normal Versus Major Versus Minor Malformations 17
Marfan Syndrome 18
Apert and De Lange Syndromes 19
Examples of Deformations 20
Example of a Deformation Sequence 21
Drug-Induced Embryopathies 22
Terminology 23

Chapter 2

Early Embryonic Development and the Placenta 27
Adult Uterus, Ovaries, and Uterine Tubes 28
Ovary, Ova, and Follicle Development 29
The Menstrual Cycle and Pregnancy 30
The First Week:
Ovulation, Fertilization and Migration Down the Uterine Tube 31
Ectopic Pregnancy 32
Tubal Pregnancy 33
Interstitial, Abdominal, and Ovarian Pregnancy 34
The Second Week:
Implantation and Extraembryonic Membrane Formation 35
The Third Week: Gastrulation 36
Events Related to Gastrulation 37
The Fourth Week: Folding of the Gastrula 38
The Vertebrate Body Plan 39
Formation of the Placenta 40
The Endometrium and Fetal Membranes 41
Placental Structure
Placental Structure 42
External Placental Structure; Maternal-Fetal Blood Barrier 43
Placental Variations 44
Placenta Previa 45
Summary of Ectodermal Derivatives 46
Summary of Endodermal Derivatives 47
Summary of Mesodermal Derivatives 48
Terminology 49

Chapter 3


No. of pages:
© 2002
Print ISBN:

About the editor

Larry Cochard

Affiliations and Expertise

The Feinberg School of Medicine, Northwestern University, Chicago, IL, USA