Neonatal Clinical Pharmacology and Therapeutics

Neonatal Clinical Pharmacology and Therapeutics

1st Edition - October 21, 1991

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  • Editors: George Rylance, David Harvey, Jacob V. Aranda
  • eBook ISBN: 9781483163000

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Neonatal Clinical Pharmacology and Therapeutics covers the significant advances in clinical pharmacology and the principles of neonatal therapeutics. This book is composed of 20 chapters that tackle various neonatal diseases and their corresponding therapeutic options. The opening chapters review the pharmacological principles and kinetics, placental drug transfer, and drug therapy in pregnancy. The next chapters consider the other aspects of clinical pharmacology, including tocolytics, oxytocin, maternal drug use, neonatal withdrawal, prophylaxis, and the effect of material analgesia and anesthetics on newborn. Considerable chapters are devoted to the treatment options of neonatal diseases, including apnea, pulmonary and systemic disorders, cardiac diseases, jaundice, hypoglycemia, and nutrient deficiencies. The remaining chapters discuss other therapeutic options, such as blood cell component therapy, the use of analgesia and muscle relaxants, and parenteral nutrition. This book is intended primarily for all doctors who care for newborn babies and clinical pharmacologists.

Table of Contents

  • List of Contributors


    1 Pharmacological Principles and Kinetics

    2 Placental Transfer of Drugs

    3 Drug Therapy in Pregnancy

    4 Tocolytics and Oxytocin

    5 Maternal Drug Use and Neonatal Withdrawal

    6 Prophylaxis for Hyaline Membrane Disease

    7 Maternal Analgesia and Anaesthesia and their Effect on the Newborn

    8 Treatment of Neonatal Apnoea

    9 Prostaglandins and the Perinatal Pulmonary and Systemic Circulation

    10 Treatment of Cardiac Disorders in the Neonate

    11 Pharmacology of Antibiotics in the Newborn

    12 Drugs and Neonatal Jaundice

    13 Investigation and Management of Hypoglycaemia

    14 Anticonvulsant Drugs

    15 Pharmacology of Vitamins A, D, E and K

    16 Oxygen Transport by the Blood, Haematinics and Blood Cell Component Therapy in the Neonate

    17 Analgesia and Muscle Relaxants

    18 Absorption of Drugs through the Skin

    19 Parenteral Nutrition

    20 Drugs in Breast Milk


Product details

  • No. of pages: 302
  • Language: English
  • Copyright: © Butterworth-Heinemann 1991
  • Published: October 21, 1991
  • Imprint: Butterworth-Heinemann
  • eBook ISBN: 9781483163000

About the Editors

George Rylance

David Harvey

Affiliations and Expertise

Consultant Paediatrician Department of Paediatrics, Hammersmith Hospital, London, UK and Professor of Paediatrics and Neonatal Medicine, Imperial College of Science, Technology and Medicine, UK

Jacob V. Aranda

Affiliations and Expertise

The Children's Hospital and Downstate, Brooklyn, NY

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