Natural Proteinase Inhibitors

Natural Proteinase Inhibitors focuses on natural inhibitors for proteolytic enzymes, which occur in plants and animals. It presents the theoretical and practical importance of the natural proteinase inhibitors of man and animal organisms. Organized into four chapters, this book starts with an overview of inhibitors for peptide and peptdohydrolases. This text then explores the important enzyme called kallikreins, which are found in the pancreas, the intestinal wall, the plasma, the submandibular gland, and the urine. Other chapters examine the various plant inhibitors, which are present in soybean, lima beans, potatoes, grains, and beetroots. This book discusses as well the inhibition of proteolytic enzymes by substances from body tissues. The final chapter deals with the prevention of uncontrolled liberation of kinins by proteinases, which is of great significance because the kinins are involved in the occurrence of pathological processes such as inflammation. Biologists and graduate students will find this book extremely useful.

Preface to the English Edition

Preface to the German Edition

Introduction

Abbreviations

Inhibitor Specificity, Determination Methods, and Definition of the Unit of Inhibiting Capacity

Specificity of the Naturally Occurring Proteinase Inhibitors

Determination Methods and Definition of the Unit of Inhibitor Activity

Plant Inhibitors

Leguminosae: Inhibitors from Soybeans (SbI) (Glycine max., Soja max., Glycine hispida, Glycine soja)

Leguminosae: Inhibitors from Lima Beans (Phaseolus lunatus)

Other Inhibitors from Leguminosae

Solanaceae: Inhibitors from Potatoes (Solanum tuberosum)

Inhibitors from Gramineae

Chenopodiaceae: Inhibitor from Beet (Beta vulgaris)

Inhibitors from Microorganisms

Action of Plant Proteinase Inhibitors in the Animal Organism

Physiological Importance of the Plant Inhibitors

Inhibitors from Animal and Human Organisms

Inhibitors from Ascaris lumbricoides suum

Inhibitors from Egg White

Inhibitor from Colostrum and Milk

Inhibitors from Blood Serum

Inhibitor from Human Urine

The Polyvalent Inhibitor from Bovine Organs

Human and Mammal Pancreas Inhibitor

Inhibitor from Submandibular Glands of Canidae and Felidae

Inhibitor from Seminal Vesicles and Semen of Mammals

Inhibitor from the Mucous Membrane of the Respiratory Passages

Inhibitor from Skin

Other Proteinase Inhibitors from Various Organs of Humans and Other Mammals

Therapeutic Possibilities of Proteinase Inhibitors

Fate of Bovine Inhibitor in the Organism

Treatment of Shock

Control of the Clotting of Blood

Treatment of Pancreatitis

Concluding Remarks

References

Subject Index