Natural and Induced Cell-Mediated Cytotoxicity - 1st Edition - ISBN: 9780125846509, 9781483269825

Natural and Induced Cell-Mediated Cytotoxicity

1st Edition

Effector and Regulatory Mechanisms

Editors: Gert Riethmüller Peter Wernet Gustavo Cudkowicz
eBook ISBN: 9781483269825
Imprint: Academic Press
Published Date: 1st January 1979
Page Count: 256
Sales tax will be calculated at check-out Price includes VAT/GST
43.99
54.95
72.95
Unavailable
Price includes VAT/GST
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

Natural and Induced Cell-Mediated Cytotoxicity: Effector and Regulatory Mechanisms contains the proceedings of the Erwin Riesch Symposium organized on the occasion of the Fifth Centennial of the University of Tübingen in Germany on October 20-23, 1977. The symposium provided a forum for reviewing the progress that has been made in understanding the effector and regulatory mechanisms underlying natural and induced cell-mediated cytotoxicity. Topics covered range from the immunobiology of natural killer cells to the role of macrophages as regulator, accessory, and effector cells in cytotoxicity.

Comprised of 27 chapters, this book begins by analyzing the characteristics of natural cytotoxic cells in mice, followed by a discussion on the generation in vivo of mouse natural cytotoxic cells and the role of cytotoxic T cells in the local defense against solid tumors. Subsequent chapters focus on the natural cytotoxicity of human lymphocytes; opposing effects of interferon on natural killer and target cells; susceptibility of cloned melanoma to natural cytotoxicity; and cell-mediated immunity against avian virus-induced tumor cells. The book also examines alternative routes of entry for cell surface antigens into the immune system before concluding with a chapter that considers interferon induction by Corynebacterium parvum.

This monograph should be of value to students, researchers, and practitioners in the fields of biology and immunology.

Table of Contents


Conferees


Preface


Acknowledgments


Immunobiology of Natural Killer Cells: Mechanisms and Regulation in the Murine System


Characteristics of Natural Cytotoxic Cells in Mice


Generation in Vivo of Mouse Natural Cytotoxic Cells


Are Cytotoxic T Cells Relevant in the Local Defense Against Solid Tumors?


Immunobiology of Natural Killer Cells: Nature of Effector Cells in the Human System


Natural Cytotoxicity of Human Lymphocytes. Immunoglobulin Dependent and Independent Systems


Characterization of Effector Cells in Human Natural Cytotoxicity


Effector Cells of Natural Cytotoxicity Against Human Melanoma Cells


Relation of Effector Mechanisms to Target Cell Origin


Mechanisms, Target Cells, and Regulation of Natural Killer Cell Activity in Man


Models for Mechanisms of Natural Cytotoxicity


Opposing Effects of Interferon on Natural Killer and Target Cells


Specificity of Natural Cytotoxic Cells Determined by Antibody


Manipulations of Natural Cytotoxicity in Tumor Patients via BCG


Susceptibility of Cloned Melanoma to Natural Cytotoxicity


Induced Cell-Mediated Cytotoxicity: Targets, Mechanisms, and Concepts


Antigen Recognition by Cytotoxic T Lymphocytes


Generation of TNP-Specific H-2-Restricted Murine Cytotoxic Cells as a Function of TNP-Cell Surface Presentation


Secondary Sendai-Specific T Effector Cells: Requirements for Restimulation, Target Cell Recognition, and Lysis


Cytotoxic T Lymphocytes Induced by H-2 Negative Stimulator Cells


Cell-Mediated Immunity Against Avian Virus-Induced Tumor Cells


Alternative Routes of Entry for Cell Surface Antigens into the Immune System


Induced Cell-Mediated Cytotoxicity: Reactivity Against Modified Self in Man


Cell-Media

Details

No. of pages:
256
Language:
English
Copyright:
© Academic Press 1979
Published:
Imprint:
Academic Press
eBook ISBN:
9781483269825

About the Editor

Gert Riethmüller

Peter Wernet

Gustavo Cudkowicz

Ratings and Reviews