Nanotechnology in Herbal Medicine

Nanotechnology in Herbal Medicine

Applications and Innovations

1st Edition - February 1, 2023

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  • Editors: Sabu Thomas, Adebola Oyedeji, Oluwatobi Oluwafemi, Rose Jacquilin PJ
  • Paperback ISBN: 9780323995276

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Description

Nanotechnology in Herbal Medicine: Applications and Innovations details how nanomaterials can be utilized to improve the therapeutic mechanisms and key properties of herbal drugs. This book guides the reader through the preparation, properties, applications, benefits and challenges of herbal nanoformulations, helping them solve fundamental and applied problems in the area of novel herbal medicines and drug delivery systems. Herbal drugs play a large role in traditional medicines, which are actively used by many cultures across the globe for the treatment of various illnesses and injuries. Despite their widespread use, herbal medicines may lead to possible health risks due to the lack of information on the chemical composition and permitted dosage.

Key Features

  • Covers a range of nanomaterial types for use in herbal medicine, including polymeric, metallic, carbon-based and magnetic nanoparticles, as well as dendrimers, liposomes, nanogels, and more
  • Explores the variety of biomedical applications for herbal nanoformulations, such as in cancer therapy, cardiovascular disease and wound healing
  • Weighs up the advantages and disadvantages of using nanotechnology in herbal medicine, with a focus on toxicological impact

Readership

Researchers and academics in the fields of biomaterials, nanopharmaceuticals, pharmacology, and polymer science; Researchers in plant science and R&D groups developing herbal pharmaceutics

Table of Contents

  • Chapter-1: Application of Nanotechnology in Herbal Medicine
    Rose Jaquilin PJ, Department of Chemical and Physical Sciences, Walter Sisulu University, South Africa
    Introduction to herbal medicines and nanotechnology
    Importance of phytomedicine in treatment
    Challenges of herbal medicine
    Bioavailability, therapeutic activity and stability of herbal medicine
    References

    Chapter -2: Nanotechnology-based Drug Delivery Systems for Herbal Medicine
    Sandhiya V, Department of Pharmaceutics, C.L.Baid Metha College of Pharmacy, India
    Introduction
    Solid lipid nanoparticles
    Polymeric micelles
    Colloidal nano-liposomes
    Nanoemulsions
    Polymeric nanoparticles
    Metallic nanoparticles
    Magnetic nanoparticles
    Carbon based nanoparticles
    Dendrimers
    References

    Chapter -3: Nano-herbal Gel Formulations
    Mohammad Abdollahi, Tehran University of Medical Sciences, Tehran Iran
    Introduction
    Applications of nano gel formulation contain herbal extract
    Applications of herbal nanogel
    Transdermal applications of herbal nanogel
    Release of herbal agents from nanogel formulations
    References

    Chapter -4: Nanoencapsulation and Characterization of Herbal Agents
    Abdelhamid Elaissari, Laboratory of Automation and Process Engineering, Claude Bernard LyonI University, Villeurbanne, France
    Introduction
    Different encapsulation techniques
    Emulsion solvent evaporation method
    Emulsion solvent diffusion method
    Ionic gelation (IG) method
    Microfluidic-assisted method
    Controlled and sustained release of bioactives
    Different Characterization techniques of nanoparticles (SEM, TEM, DLS, AFM etc.)
    References

    Chapter -5: Metal and Carbon-based Nano-herbal Formulations
    Chuong Pham-Huy; Faculty of Pharmacy, University of Paris V, 75006 Paris, France
    Introduction
    Synthesis of metal based nano-herbal formulations
    Controlled and sustained release of bioactives
    Applications of herbal agents loaded with carbon nanotubes
    References

    Chapter -6: Emulsion-based Nano-herbal Formulations
    Sirikarn Pengon, Department of Pharmaceutical Technology, Faculty of Pharmacy, Salpicon University, Thailand
    Introduction
    Nano self-emulsifying delivery systems for bioactive phytochemicals
    Antimicrobial nanoemulsions contain herbal extract
    Essential oil-loaded nanoemulsions
    Applications of nano-herbal emulsions
    References

    Chapter -7: Liposomes and Lipid Nanoparticle-based Herbal Formulations
    Nazish Jahan, Department of Chemistry, University of Agriculture, Faisalabad, Pakistan
    Introduction
    Phyto phospholipid
    Niosomes
    Nanostructured lipid carriers
    Solid lipid nanoparticles (SLNs) for herbal medicine
    Lipid nanocarriers for phytomedicine
    Applications of liposomes-based phytoconstituents formulations
    References

    Chapter -8: Dendrimer-based Drug Delivery Systems for Herbal Medicine
    Yiyun Cheng, Department of Chemistry, University of Science and Technology of China, China
    Introduction
    Dendrimers in modern therapeutic era
    Common types of dendrimers used in herbal medicine their properties
    Features of herbal drug incorporated in dendrimers for drug delivery
    Applications of dendrimer nanocarriers in different disease conditions
    References

    Chapter-9: Phytoconstituent Liquid Crystalline Systems
    May S Frag, Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Egypt
    Introduction
    Classification of liquid crystalline systems
    LC-based drug delivery systems for herbal medicine
    Development of plant essential oil incorporated LC systems
    Applications
    References

    Chapter -10:   Biosynthesis of Nanoparticles Using Plant Extracts
    Palaniselvam Kuppusamy, Biomaterial and Biosensor Laboratory, University Malaysia Pahang, Malaysia
    Introduction
    Properties of nanoparticles
    Role of plants in nanoparticles synthesis
    Biosynthesis of nanoparticles using plant extract
    Factors affecting synthesis of bionanoparticles
    Advantages of green synthesis of nanoparticles
    Phytosynthesis of silver nanoparticles
    Antimicrobial activity of phytosynthesized silver nanoparticles
    Applications of plant mediated gold, and zinc nanoparticles
    References

    Chapter-11: Plant Extract Loaded Nanocarriers
    Oliveira, Department of Biological & Agricultural Engineering, Texas A &M University, College Station, United States
    Introduction
    Encapsulation of different plant extracts using different nanocarriers
    Nano herbal extract formulation: synthesis and characterization and applications
    Release mechanism
    References

    Chapter-12: Herbal Nanomedicines in the Treatment of Viral Diseases
    Lavanya Singh, Department of Virology, National Health Laboratory Service, University of KwaZulu-Natal, Durban, South Africa
    Introduction
    Mechanism of action of plant derived antiviral agents
    Pharmacological and biological mechanisms of herbal agents against infectious diseases.
    Role of nanotechnology in treatment of viral infections
    Phyto nano medicine used for the treatment of infectious diseases.
    References

    Chapter-13: Herbal Nanomedicine in Cancer therapy
    Dina A. Hafez, Department of Industrial Pharmacy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt
    Introduction
    Therapeutic significance of phyto-therapeutics
    Herbal medicines with anti-cancer activity
    Nanotechnology based drug delivery systems for plant based anticancer agents
    Clinical trials of herbal nanomedicine with anti-cancer effect
    Herbal nanomedicine: Challenges and benefits
    References

    Chapter-14: Natural and Synthetic Polymer-based Nano-herbal Pharmaceutics
    Introduction
    Natural polymers used in pharmaceutical nanotechnology
    Chitosan based nanocarriers
    Cellulose based nanocarriers
    Algenic acid based nanocarriers
    Gelatin nanocarriers
    Collagen nanoparticles
    Synthetic polymer-based nano-herbal pharmaceutics
    Controlled and sustained release of herbal medicine
    References

    Chapter-15: Herbal Nanomedicine for Wound Healing
    Marziyeh Hajialyani, Pharmaceutical Sciences Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
    Introduction
    Role of nanotechnology in promoting wound healing
    Medicinal plants for wound healing
    Polymer-based plant extract immobilized scaffolds in wound healing applications
    Medicinal plant based wound dressings made of electrospun nanofibers
    Nano fibers contain essential oils for wound healing applications
    Nano-drug delivery systems loaded by phytochemicals for wound healing
    References

    Chapter -16: Phyto-nanomedicine for Disease Treatment
    Yu-Jie Zhang, Guangdong Provincial Key Laboratory of Food, Department of Nutrition, Sun Yat-Sen University, China
    Introduction
    Treatment of diabetes using herbal medicine
    Phyto-nanomedicine in diabetes treatment
    Phyto-nanomedicine in treatment of cardiovascular diseases
    Role of phyto-nanomedicine in neuroprotection
    References

    Chapter -19: Nano-herbal Medicine: Challenges and Future Perspectives
    Introduction
    Advantages of nano herbal nanomedicine
    Toxicity
    Challenges and future perspective
    References

Product details

  • No. of pages: 450
  • Language: English
  • Copyright: © Woodhead Publishing 2023
  • Published: February 1, 2023
  • Imprint: Woodhead Publishing
  • Paperback ISBN: 9780323995276

About the Editors

Sabu Thomas

Professor Thomas is an outstanding leader with sustained international acclaims for his work in Nanoscience, Polymer Science and Engineering, Polymer Nanocomposites, Elastomers, Polymer Blends, Interpenetrating Polymer Networks, Polymer Membranes, Green Composites and Nanocomposites, Nanomedicine and Green Nanotechnology. Dr. Thomas’s ground-breaking inventions in polymer nanocomposites, polymer blends, green bionanotechnological and nano-biomedical sciences, have made transformative differences in the development of new materials for biomedical, automotive, space, and housing fields. Professor Thomas has published over 1000 peer reviewed research papers, reviews and book chapters. He has co-edited 150 books published by Royal Society, Wiley, Woodhead, Elsevier, CRC Press, Springer, and Nova Science. He is the inventor of 16 patents.

Affiliations and Expertise

Vice Chancellor and Full Professor, Mahatma Gandhi University, Kottayam, Kerala, India

Adebola Oyedeji

Prof. Oyedeji is Professor of Organic Chemistry at Walter Sisulu University (WSU), Department of Chemical and Physical Sciences, South Africa, where she teaches organic chemistry at both undergraduate and postgraduate level as well as leads a natural product research group. She obtained her Master’s degree in Polymer Chemistry from the University of Port Harcourt, Nigeria, and her PhD degree in Organic Chemistry from University of Ibadan, Nigeria. Her work hinges on natural products chemistry with special interest in finding the medicinal values of terpenoids class of compounds in medicinal plants. Prof. Oyedeji is a recipient of several awards including TWAS (2003), NRF South Africa (2003-2004), National Research Foundation Rated Scientist (2010-2015 & 2016-2021), WSU Established Female Researcher (2017), WSU Vice Chancellor Awards for Excellence in Research (2017), Pre-commercialization innovation product developed (2019), Engagement through Professional/Discipline-based Service Provision (2019) and Engagement through Research and Scholarship (2019). She is a fellow of Chemical Society of Nigeria (CNS), member of Third World Organization for Women in Science (TWOWS), member of South African Chemical Institution (SACI) and Royal Society of Chemistry (RSC). She is also an affiliated member of the International Union of Pure and Applied Chemistry (IUPAC).

Affiliations and Expertise

Professor, Department of Chemical and Physical Sciences, Walter Sisulu University (WSU), South Africa

Oluwatobi Oluwafemi

Professor Oluwafemi is a fully-fledged academic that is involved in Teaching & Learning, Research, Community Engagement, staff and student mentorship among many other activities. His research interest is in the synthesis of binary, ternary and quaternary semiconductor nanomaterial and nanostructures such as quantum dots, metal nanomaterials, core-shells, doped nanostructures and polymer nanocomposites for different applications which includes biological, (basically for cancer treatment ie imaging, labelling, drug delivery photodynamic therapy and photothermal therapy), optical (development of optical devices), environmental (sensing and determination of environmental pollutants), nanotoxicology and water treatment. He is also involved in the indigenous knowledge system (IKS) for value added chain using different South African medicinal plants. This involves isolation, extraction, biological activity testing, and synthesis of nanomaterial using the plant extract and packaging for pharmaceutical purposes.

Affiliations and Expertise

Department of Applied Chemistry, Centre for Nanomaterials Science Research, University of Johannesburg, Johannesburg, South Africa

Rose Jacquilin PJ

Rose Jaquilin PJ is currently pursuing her PhD degree at Walter Sisulu University, South Africa. She holds a Bachelor’s degree in Chemistry and a Master’s degree in Polymer Chemistry from Kerala University, Trivandrum, Kerala, India. She has nine years’ research experience at Syngene International Ltd, a leading pharmaceutical company in India. Her research areas include bio- and specialty-polymer synthesis, polymer grafting, hydrogel and dendrimer synthesis, controlled radical (ATRP, RAFT), anionic and cationic polymerization techniques. Her current research work includes synthesis and characterization of herbal nanomaterials for different applications.

Affiliations and Expertise

Department of Chemical and Physical Sciences, Walter Sisulu University, South Africa

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