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Nanotechnology in Cancer Management: Precise Diagnostics toward Personalized Health Care provides a well-focused and comprehensive overview of technologies involved in early stage cancer diagnostics via the detection of various cancer biomarkers, both in-vitro and in-vivo. The book briefly describes the advancement in cancer biomarker research relating to cancer diagnostics, covering fundamental aspects of various techniques, especially transduction methodologies, such as electrochemical, optical, magnetic, etc. In addition, it describes approaches on how to make options cost-effective, scalable for clinical application, and user-friendly. Advancements in technology related to device miniaturization, performance improvement and point-of-care applications round out discussions.
Final sections cover future challenges, the prospects of various techniques, and how the introduction of nanotechnology in cancer management in a personalized manner is useful.
- Includes smart sensing materials such as smart electro-active nanomaterials, sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical system, and device integration and interfacing for point-of-care applications
- Describes each component involved in the development of an efficient cancer diagnostics system
- Focuses on fundamental and applied concepts of the technologies, along with the related mechanisms proposed for diagnostics of cancer
- Enhances fundamental understandings of the concepts and development of nanotechnology based analytical tools and novel techniques for early stage cancer diagnostics and management
Post-graduates, researchers, and scientists in the field of chemistry, physics, biology, engineering, biomaterials, and medicine; medical professionals and others in interdisciplinary fields of science and technology as well as pharmaceutical materials synthesis and nanotechnology; industries involved in developing medical products and procedures
1. Introduction: Background, diagnostics, cancer biomarkers, state-of-art
2. Electrochemical Detection: CV/DPV/Impedance
3. Fluorescence microscopy: Organic dye/nanoparticles/quantum dots and spectroscopy
4. Raman spectrophotometer: SERS nanotags (Au/Ag), confocal Raman microscopy
5. Sequencing: DNA analysis
6. Bioinformatics: Computer programming
7. Magnetic: Magnetic based sensing
8. Lab on a chip: Microfluidics
9. Imaging: Electron microscopy (AFM/SEM/TEM): Shape and size-based analysis
10. Scale up of rapid diagnostics for clinical application: Device development for clinical application
11. Challenges and future prospects of nano-enabled cancer management
- No. of pages:
- © Elsevier 2021
- 18th May 2021
- eBook ISBN:
- Paperback ISBN:
Dr. Kamil Reza Khondakar obtained his doctoral degree from the Centre of Personalised Nanomedicine in the Trau group, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia. He is currently involved in the multiple surface marker profiling of cancer cells and monitor the drug sensitivity effect on the cell surface markers in a Raman (SERS) based microfluidic chip. The aim of his studies is focused on the development of next-generation diagnostics chips for multiple biomarker detection on a single chip to understand the tumor heterogeneity and provide an early detection strategy for cancer management. Prior to this, he worked as a researcher in DST Center at Biomedical Instrumentation Section, National Physical Laboratory, India. His research activities included development of thin film-based microelectrodes using various nanostructures, nanocomposites for biomedical applications. He received awards and honors due to his contributions to the field of biomedical technology. He was awarded International Postgraduate Research Scholarship (IPRS) from Government of Australia, and University of Queensland Centennial Scholarship (UQCent) from The University of Queensland, Australia. He was invited to give a talk at ‘Biosensor 2018’ conference at Miami, USA.
Centre for Personalised Nanomedicine, Australian Insititute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Australia
Dr. Kaushik I M.Sc., Ph.D., Fellow-Indian Chemical Society I, an assistant professor of chemistry at Florida Polytechnic University, is exploring nano-technology, material science, thin films, miniaturized sensors, electrochemistry, electrochemical biosensors, nanomedicine, drug delivery to CNS, and biomedical engineering for health wellness. Dr. Kaushik received his Ph.D. (chemistry and nano-enabled biosensors) in collaboration with National Physical Laboratory and Jamia Milia Islamia, New Delhi, India. During his research, Dr. Kaushik has been engaged in design and development of various electro-active nanostructures for electrochemical biosensor and nanomedicine for health care. His research interests include nano-bio-technology, analytical systems, design & develop nanostructures, nanocarriers for drug delivery, nano-therapeutics for CNS diseases, on-demand site-specific release of therapeutic agents, exploring personalized nano-medicines, biosensors, point-of-care sensing devices, and related areas of health care monitoring.
Assistant Professor of Chemistry, Department of Natural Sciences, Division of Sciences, Arts & Mathematics (SAM), Florida Polytechnic University, Lakeland, FL 33805-8531 USA
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