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Nanotechnology in Cancer Management: Precise Diagnostics toward Personalized Health Care provides a well-focused and comprehensive overview of technologies involved in early stage cancer diagnostics via the detection of various cancer biomarkers, both in-vitro and in-vivo. The book briefly describes the advancement in cancer biomarker research relating to cancer diagnostics, covering fundamental aspects of various techniques, especially transduction methodologies, such as electrochemical, optical, magnetic, etc. In addition, it describes approaches on how to make options cost-effective, scalable for clinical application, and user-friendly. Advancements in technology related to device miniaturization, performance improvement and point-of-care applications round out discussions.
Final sections cover future challenges, the prospects of various techniques, and how the introduction of nanotechnology in cancer management in a personalized manner is useful.
- Includes smart sensing materials such as smart electro-active nanomaterials, sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical system, and device integration and interfacing for point-of-care applications
- Describes each component involved in the development of an efficient cancer diagnostics system
- Focuses on fundamental and applied concepts of the technologies, along with the related mechanisms proposed for diagnostics of cancer
- Enhances fundamental understandings of the concepts and development of nanotechnology based analytical tools and novel techniques for early stage cancer diagnostics and management
Post-graduates, researchers, and scientists in the field of chemistry, physics, biology, engineering, biomaterials, and medicine; medical professionals and others in interdisciplinary fields of science and technology as well as pharmaceutical materials synthesis and nanotechnology; industries involved in developing medical products and procedures
1. Introduction: Background, diagnostics, cancer biomarkers, state-of-art
2. Electrochemical Detection: CV/DPV/Impedance
3. Fluorescence microscopy: Organic dye/nanoparticles/quantum dots and spectroscopy
4. Raman spectrophotometer: SERS nanotags (Au/Ag), confocal Raman microscopy
5. Sequencing: DNA analysis
6. Bioinformatics: Computer programming
7. Magnetic: Magnetic based sensing
8. Lab on a chip: Microfluidics
9. Imaging: Electron microscopy (AFM/SEM/TEM): Shape and size based analysis
10. Scale up of rapid diagnostics for clinical application: Device development for clinical application
11. Challenges and future prospects of nano-enabled cancer management
- No. of pages:
- © Elsevier 2021
- 1st May 2021
- Paperback ISBN:
Kamil Reza Khondakar is actively involved in developing chip based technology to detect cancer biomarker for the rapid and cost-effective diagnostics of targeted cancer at the Centre of Personalised Medicine in Trau group, at the University of Queensland, Australia. He is a well achieved young scientist and his credential reflects though good quality publications in high impact factor journal such as Small, Biosensor and Bioelectronics, Langmuir etc. He has presented his work in various national and international conferences and workshops. His future research activities include development of biosensors based on nanostructures, nanocomposites utilizing various platforms including microfluidic chip for biomedical applications.
Centre for Personalised Nanomedicine, Australian Insititute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Australia
Dr. Kaushik I M.Sc., Ph.D., Fellow-Indian Chemical Society I, as assistant professor of chemistry at Florida Polytechnic University, is exploring nano-technology, material science, thin films, miniaturized sensors, electrochemistry, electrochemical biosensors, nanomedicine, drug delivery to CNS, and biomedical engineering for health wellness. Dr. Kaushik received his Ph.D. (chemistry and nano-enabled biosensors) in collaboration with National Physical Laboratory and Jamia Milia Islamia, New Delhi, India. Prior to move to Polytech, he has worked as an Assistant Professor to explore “magnetic nanomedicine along with drug deliver to the brain for the CND diseases management and miniaturized electrochemical sensing systems for personalized health wellness” at Center of Personalized Nanomedicine, Institute of NeuroImmune Pharmacology, Department of Immunology and Nano-Medicine, Herbert Wertheim College of Medicine, Florida International University (FIU), Miami USA. He is the recipient of various reputed awards for his service in the area of nano-biotechnology for health care. His excellent research credentials reflect by his four edited books, over 100 international research peer reviewed publications, and three patents in the area of nanomedicine and smart biosensors for personalized health care. In the course of his research, Dr. Kaushik has been engaged in design and development of various electro-active nanostructures for electrochemical biosensor and nanomedicne for health care. His research interests include nano-bio-technology, analytical systems, design & develop nanostructures, nanocarries for drug delivery, nano-therapeutics for CNS diseases, on-demand site-specific release of therapeutic agents, exploring personalized nano-medicines, biosensors, point-of-care sensing devices, and related areas of health care monitoring.
Assistant Professor of Chemistry, College of Innovation and technology, Department of Natural Science, Florida Polytechnique University
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