Nanostructured Biomaterials for Regenerative Medicine

Nanostructured Biomaterials for Regenerative Medicine

1st Edition - October 5, 2019

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  • Editors: Vincenzo Guarino, Michele Iafisco, Silvia Spriano
  • Paperback ISBN: 9780081025949
  • eBook ISBN: 9780081025956

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Nanostructured Biomaterials for Regenerative Medicine focuses on the definition of new trends for the design of biomaterials for biomedical applications. It includes the ex novo synthesis as well as technological strategies to manipulate them into appropriate two-dimensional (2D) and three-dimensional (3D) forms, in order to impart all the main physical, chemical, structural and biological properties requested to achieve desired clinical efficacy. This book aims at offering a concise overview of innovative platforms based on nanostructured biomaterials as a function of their chemical nature - established by a consolidated material classification i.e., polymer, ceramics and metals. For each class, emerging bioinspired systems with rapid expansion in the biomedical research area and fabricated via new enabling technologies will be proposed for the use in tissue repair/regeneration and nanomedicine. This book is an essential resource for researchers, academics and professionals interested in the potential of nanostructured biomaterials for regenerative medicine.

Key Features

  • Classifies materials into three classes for comprehensive discussion
  • Discusses design techniques to create innovative nanostructured biomaterials
  • Looks at enabling technologies and strategies for emerging applications


Materials scientists and biomedical engineers

Table of Contents

  • 1. Introducing biomaterials for tissue repair and regeneration

    2. Regulatory landscape of nanostructured biomaterials for tissue regeneration

    3. Nanostructured biomaterials for regenerative medicine: Clinical perspectives

    4. Nanostructured biomaterials with antimicrobial activity for tissue engineering

    Part One - Polymers and composites

    5. Molecularly imprinted polymers for selective recognition in regenerative medicine

    6. Polysaccharide-based hybrid materials for molecular release applications

    7. Patterned nanocomposites generated via electric/magnetic fields for hierarchical tissue regeneration

    Part Two - Ceramics

    8. Nanostructured calcium phosphates for hard tissue engineering and nanomedicine

    9. Silicate-based nanoceramics in regenerative medicine

    10. Bioactive glass-ceramics: From macro to nano

    11. Inorganic nanoparticle-based biomaterials for regenerative medicine

    Part Three - Metals

    12. Surface topographies on the micro and nanoscale of metal alloys for tissue regeneration

    13. Fast and effective osseointegration of dental, spinal, and orthopedic implants through tailored chemistry of inorganic surfaces

    14. Micro and nano-needles as innovative approach in nanomedicine

    15. Metal nanoscale systems functionalized with organic compounds

Product details

  • No. of pages: 466
  • Language: English
  • Copyright: © Woodhead Publishing 2019
  • Published: October 5, 2019
  • Imprint: Woodhead Publishing
  • Paperback ISBN: 9780081025949
  • eBook ISBN: 9780081025956

About the Editors

Vincenzo Guarino

Vincenzo Guarino is Senior Researcher at the Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, Naples, Italy. His research interests include biomaterials, tissue engineering, scaffold design, and the fabrication and characterization of polymer and composite materials for biomedical applications.

Affiliations and Expertise

Researcher, Institute of Polymers, Composite and Biomaterials (IPCB), National Research Council (CNR), Napoli, Italy

Michele Iafisco

Michele Iafisco is a researcher at Institute of Science and Technology for Ceramics (ISTEC) of the National Research Council (CNR) in Faenza (RA), Italy since 2013. He graduated in Chemistry in 2005 from the Alma Mater Studiorum, University of Bologna. From the same university he obtained the Ph.D. degree in Chemical Science in April 2009. His research interests include biomaterials, biomineralization, nanomedicine, calcium phosphates and bioceramics. He has authored more than 90 papers in international peer-reviewed journals, 15 book chapters and 6 patents. He is member of the editorial boards of several international journals and expert evaluator for the European Commission and for other European research agencies. In 2015 he was recipient of the prize “Ricercatamente 2014” for the best research activity of most promising young researcher “under 35” at the National Research Council of Italy in the field “Chemical Sciences and Materials Technology" and of the IUPAC-2015 Young Chemist Travel Award. From 01/01/2016, he is scientific responsible of the Research Line on “Nanostructured materials for dental and maxillofacial applications” of the ISTEC-CNR.

Affiliations and Expertise

Researcher, Institute of Science and Technology for Ceramics (ISTEC), National Research Council (CNR), Faenza (RA), Italy.

Silvia Spriano

Prof. S. Spriano is Associate Professor at the Applied Sciences and Technology Department of Politecnico di Torino (DISAT – POLITO). She has 20 years experience in metallic materials and biomaterials, in particular her research activities cover: surface modification and characterization of metallic alloys for biomedical applications, functionalization of biomaterials with natural biomolecules, bioactivity, shape memory and pseudo-elastic alloys, antibacterial and anti-fouling surfaces, surfaces with enhanced osteointegration ability, surface for guided soft tissues generation, low friction composite materials with graphene/nano-graphite and coatings for materials for high wear and/or fretting resistance.

Affiliations and Expertise

Associate Professor, Department of Applied Science and Technology (DISAT), Politecnico di Torino, Torino, Italy

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