
Nanoscale Fabrication, Optimization, Scale-up and Biological Aspects of Pharmaceutical Nanotechnology
Description
Key Features
- Shows how nanomanufacturing techniques can help to create more effective, cheaper pharmaceutical products
- Explores how nanofabrication techniques developed in the lab have been translated to commercial applications in recent years
- Explains safety and regulatory aspects of the use of nanomanufacturing processes in the pharmaceutical industry
Readership
Pharmaceutical scientists, biomaterials scientists, toxicologists, biomedical engineers, medicinal chemists and postgraduate students specializing in the areas of nanomedicine, bionanomaterials and nanotechnology applications in healthcare
Table of Contents
1. Fabrication of polymeric core-shell nanostructures
2. Emulsification-diffusion method to obtain polymeric nanoparticles: two decades of research
3. Tools and Techniques for the optimized synthesis, reproducibility and scale up of desired nanostructures from plant derived material and their role in pharmaceutical properties
4. Scale up of biopharmaceuticals production
5. Physicochemical and morphological characterization of pharmaceutical nanocarriers and mathematical modelling of drug encapsulation/release mass transfer processes
6. Biopharmaceutics and pharmacokinetics of multifunctional nanoparticles
7. Technological delivery systems to improve biopharmaceutical properties
8. From physicochemically stable nanocarriers to targeted drug delivery: in-vivo pharmacokinetic, pharmacodynamic and biodistribution studies
9. Sterile dosage forms loaded nanosystems for parenteral, nasal, pulmonary and ocular administration
10. Quantitative Characterization of Targeted Nanoparticulate Formulations for Prediction of Clinical Efficacy
11. Analytical tools for reliable in vitro and in vivo performance testing of drug nanocrystals
12. Application of one-step affinity purification of drug-binding proteins with practical magnetic nanoparticles to drug discovery
13. Molecularly Imprinted Polymers as Separation Tools
14. Detection of DNA damage induced by nanomaterials
15. Pharmacological usage of an enzyme inhibitor – a selective inhibitor of 3-mercaptopyruvate sulfurtransferase reaction intermediate to control generation of polysulfide
16. Regulatory Consideration in Nanotechnology Based Drug Products
Product details
- No. of pages: 696
- Language: English
- Copyright: © Elsevier 2017
- Published: November 28, 2017
- Imprint: Elsevier
- Paperback ISBN: 9780128136294
- eBook ISBN: 9780128136300
About the Editor
Alexandru Grumezescu
Affiliations and Expertise
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